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Aspin: neurosurgical aspirin intervention prognostic study — perioperative continuation versus discontinuation of aspirin in lumbar spinal surgery, a randomized controlled, noninferiority trial
RationaleAspirin is typically discontinued in cranial and spinal surgery because of the increased risk of hemorrhagic complications, but comes...
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The Effects of Aspirin dose in Children with Congenital and Acquired Heart Disease. Results from the Paediatric Study of Aspirin Efficacy using Diagnostic and Monitoring Tools (PAED-M)
The optimal dose of aspirin required in children with congenital and acquired heart disease is not known. The primary aim of this prospective...
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Does an Aspirin a Day Take the MASLD Away?
Although aspirin is deeply rooted in the most ancient history of medicine, the mechanism of action of this drug was only identified a few decades...
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Missed opportunities in aspirin prescribing for preeclampsia prevention
BackgroundHypertensive disorders of pregnancy, including preeclampsia, are a leading cause of perinatal morbidity and mortality in the United States,...
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Inflammation, Frailty, and Aspirin Use in the Physicians’ Health Study: A Pilot Study
Whether anti-inflammatory medications such as aspirin can lower the risk of frailty is an active area of investigation. In previous studies, we...
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The Cost-Effectiveness of Rivaroxaban Plus Aspirin Compared with Aspirin Alone in the COMPASS Trial: A US Perspective
BackgroundRivaroxaban 2.5 mg twice daily with aspirin 100 mg daily was shown to be better than aspirin 100 mg daily for preventing cardiovascular...
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Aspirin as a chemopreventive agent for cutaneous melanoma: a literature review
Rising melanoma rates have spurred interest in preventive strategies. Nonsteroidal anti-inflammatory drugs (NSAIDs), particularly aspirin, show...
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Respiratory Exposure Tests in Aspirin Exacerbated Respiratory Disease
Purpose of reviewControlled oral provocation test with aspirin is considered the “gold standard” for diagnosing hypersensitivity to NSAIDs...
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Effect of aspirin on blood pressure in hypertensive patients: a systematic review and meta-analysis
IntroductionAspirin is widely used for secondary prevention in patients with hypertension. However, previous studies mainly focused on the preventive...
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Target trial emulation of aspirin after diagnosis of colorectal polyps
Backgound and AimsPrevious research on the potential chemoprotective effect of aspirin for colorectal cancer (CRC) shows conflicting results. We...
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Pharmacodynamic Comparison of Two Aspirin Formulations in the Caribbean: The ARC Study
IntroductionThis prospective, single-arm, crossover pharmacodynamic study assessed the effect of Bayer ® low-dose enteric-coated aspirin 81 mg...
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Aspirin Desensitization in Treatment of Chronic Rhinosinusitis with Nasal Polyposis: Current Protocols and Evidence
Purpose of ReviewAspirin-exacerbated respiratory disease (AERD), or NSAID-exacerbated respiratory disease (NERD), is a heterogeneous inflammatory...
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Omeprazole taken once every other day can effectively prevent aspirin-induced gastrointestinal mucosal damage in rats
BackgroundProton-pump inhibitors (PPIs) prevent aspirin-associated gastric and duodenal mucosal damage. However, long-term use of PPIs can lead to...
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Safety and complications of continuation of aspirin therapy in patients undergoing robot-assisted laparoscopic simple prostatectomy
To evaluate the safety and feasibility of continued perioperative aspirin at the time of robotic assisted simple prostatectomy (RASP). We performed a...
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Association between aspirin use and risk of dementia: a systematic review and meta-analysis
PurposeDementia and Alzheimer’s disease (AD) pose significant challenges to public health globally with no effective treatment strategies...
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Aspirin in Patients with Viral Hepatitis: Systematic Review and Meta-Analysis of Observational Studies
BackgroundHepatocellular carcinoma (HCC) is a disease demonstrating increasing morbidity and mortality, especially in patients with chronic viral...
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The impact of aspirin use on outcomes in patients with inflammatory bowel disease: Insights from a national database
BackgroundInflammatory bowel disease (IBD) is an inflammatory disorder that can increase the risk of mortality. Aspirin is an anti-inflammatory drug...
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Aspirin prevents estrogen deficiency-induced bone loss by inhibiting osteoclastogenesis and promoting osteogenesis
BackgroundAspirin is a commonly used antipyretic, analgesic, and anti-inflammatory drug. Numerous researches have demonstrated that aspirin exerts...
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The Infarct-Limiting Effect of Remote Ischemic Conditioning in Rats Is Not Affected by Aspirin
PurposeRemote ischemic conditioning (RIC) has been shown to be a powerful cardioprotective therapy in animal models. However, a protective effect in...
