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Antibacterial efficacy of indigenous Pakistani honey against extensively drug-resistant clinical isolates of Salmonella enterica serovar Typhi: an alternative option to combat antimicrobial resistance
BackgroundExtensively drug-resistant (XDR) Salmonella enterica serovar Typhi ( S. Typhi) poses a grave threat to public health due to increased...
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Pharmacotechnical aspects of a stable probiotic formulation toward multidrug-resistance antibacterial activity: design and quality control
As a well-known group of the probiotic family, the Lactobacillus has increasingly contributed to hindering the growth of pathogens, particularly...
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Unravelling patient pathways in the context of antibacterial resistance in East Africa
BackgroundA key factor driving the development and maintenance of antibacterial resistance (ABR) is individuals’ use of antibiotics (ABs) to treat...
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Drug resistance and influencing factors of biofilm bacteria in upper urinary calculi patients with double J stent indwelling
ObjectiveTo analyze the distribution and drug resistance of biofilm bacteria infected with upper urinary calculi patients with double J stent...
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Antimicrobial resistance crisis: could artificial intelligence be the solution?
Antimicrobial resistance is a global public health threat, and the World Health Organization (WHO) has announced a priority list of the most...
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Formulation of Cinnamon (Cinnamomum verum) oil loaded solid lipid nanoparticles and evaluation of its antibacterial activity against Multi-drug Resistant Escherichia coli
Today, the increment in microbial resistance has guided the researches focus into new antimicrobial compounds or transmission systems. Escherichia coli ...
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How gallic acid regulates molecular signaling: role in cancer drug resistance
Cancer is one of the deadliest and most heterogeneous diseases. Cancers often develop drug resistance, which can lead to treatment failure or...
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Evaluating the antibacterial effect of meropenem-loaded chitosan/sodium tripolyphosphate (TPP) nanoparticles on Acinetobacter baumannii isolated from hospitalized patients
BackgroundAcinetobacter baumannii is a health threat due to its antibiotic resistance. Herein, antibiotic susceptibility and its association with...
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Patients with Obesity Should be Recognised as a Special Patient Population During Drug Development of Antibacterial and Antifungal Agents; A Call to Action
Individuals with obesity are at increased risk of develo** infectious diseases. Timely administration of an effective dose of an antimicrobial...
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Invitro antibacterial activity of bark, leaf and root extracts of combretum molle plant against streptococcus equi isolated from clinical cases of strangles in donkeys and horses
BackgroundEffective therapy for many infections is becoming difficult due to the evolutionary development of drug resistance, and hence, the...
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Advances in contezolid: novel oxazolidinone antibacterial in Gram-positive treatment
PurposeThe principal objective of this project was to review and thoroughly examine the chemical characteristics, pharmacological activity, and...
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Overcoming Klebsiella pneumoniae antibiotic resistance: new insights into mechanisms and drug discovery
BackgroundDue to antibiotic overuse, numerous organisms have evolved multidrug resistance, a global health crisis. Klebsiella pneumoniae ( K....
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Impact of Antimicrobial Stewardship Programs on Antibiotic Use and Drug Resistance: Analysis of Data from Maternal and Child Health Care Hospitals in Hubei Province, China
ObjectiveTo evaluate the impact of Antimicrobial Stewardship Programs (ASPs) on antibiotic use and drug resistance.
MethodsThis was a retrospective,...
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In vitro antibacterial activity of fruit pulp extracts of Tamarindus indica against Staphylococcus aureus and Klebsiella pneumoniae
BackgroundInfectious diseases are increasingly recognized as public health concern worldwide as the rising incidence in multidrug resistance...
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To quest new targets of Plasmodium parasite and their potential inhibitors to combat antimalarial drug resistance
Malaria remains a global health challenge with significant mortality and morbidity annually, with resistant parasite strains complicating treatment...
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Antibacterial Activity of Plants in Cirsium: A Comprehensive Review
As ethnic medicine, the whole grass of plants in Cirsium was used as antimicrobial. This review focuses on the antimicrobial activity of plants in Cirsium...
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Can the UK ‘Netflix’ Payment Model Boost the Antibacterial Pipeline?
The silent pandemic of antimicrobial resistance (AMR) is a global issue needing prompt attention. A comprehensive one-health approach across human...
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Insights into the potential dual-antibacterial mechanism of Kelisha capsule on Escherichia coli
Traditional Chinese medicine (TCM), AYURVEDA and Indian medicine are essential in disease prevention and treatment. Kelisha capsule ( KLSC ), a TCM...
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Nanoformulated herbal compounds: enhanced antibacterial efficacy of camphor and thymol-loaded nanogels
Herbal components are highly useful assets for the advancement of novel antibacterial drugs. Nanotechnology holds great promise as an approach to...
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Antibacterial activity of the antimicrobial peptide PMAP-36 in combination with tetracycline against porcine extraintestinal pathogenic Escherichia coli in vitro and in vivo
The increase in the emergence of antimicrobial resistance has led to great challenges in controlling porcine extraintestinal pathogenic Escherichia...
