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Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway
BackgroundAltered lipid profiles are frequently present in cancer, and it is necessary to elucidate the role of changed lipid profiles in...
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The Effect of Crackers Enriched with Camelina Sativa Oil on Omega-3 Serum Fatty Acid Composition in Older Adults: A Randomized Placebo-Controlled Pilot Trial
BackgroundCamelina sativa oil is one of the richest dietary sources of omega-3, with polyunsaturated fatty acids amounts of over 50%, linolenic acid...
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Association between dietary intake of polyunsaturated fatty acid and prevalence of hypertension in U.S. adults: A cross-sectional study using data from NHANES 2009–2016
This study aimed to evaluate the association between dietary polyunsaturated fatty acid (PUFA) intake and the prevalence of hypertension in U.S....
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Differential methylation of linoleic acid pathway genes is associated with PTSD symptoms – a longitudinal study with Burundian soldiers returning from a war zone
Soldiers may be exposed to traumatic stress during combat deployment and thus are at risk for develo** posttraumatic stress disorder (PTSD)....
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No association between long-chain n-3 fatty acid intake during pregnancy and risk of type 1 diabetes in offspring in two large Scandinavian pregnancy cohorts
Aims/hypothesisThe aim of this study was to investigate whether higher dietary intake of marine n -3 fatty acids during pregnancy is associated with...
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The multidimensional benefits of eicosapentaenoic acid: from heart health to inflammatory control
Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fatty fish and fish oil supplements. Over the past few decades, research has suggested...
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Metabolic profiling of patients with different idiopathic inflammatory myopathy subtypes reveals potential biomarkers in plasma
Idiopathic inflammatory myopathy (IIM) are heterogeneous autoimmune diseases that primarily affect the proximal muscles. IIM subtypes include...
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Exploring the causal role of multiple metabolites on ovarian cancer: a two sample Mendelian randomization study
BackgroundThe mechanisms and risk factors underlying ovarian cancer (OC) remain under investigation, making the identification of new prognostic...
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Development of fatty acid metabolism score based on gene signature for predicting prognosis and immunotherapy response in colon cancer
PurposeMetabolic reprogramming is a novel hallmark and therapeutic target of cancer. Our study aimed to establish fatty acid metabolism-associated...
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Alyssum homolocarpum seed oil (AHSO), containing natural alpha linolenic acid, stearic acid, myristic acid and β-sitosterol, increases proliferation and differentiation of neural stem cells in vitro
BackgroundEmbryonic neural stem cells (eNSCs) are immature precursors of the central nervous system (CNS), with self-renewal and multipotential...
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Comprehensive fatty acid fractionation profilling in preeclampsia: a case control study with multivariable analysis
BackgroundPreeclampsia is a complication during pregnancy characterised by new-onset hypertension and proteinuria that develops after 20 weeks of...
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Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis
BackgroundWomen suffer from various distress and disturbances after menopause, including osteoporosis, a risk factor associated with multiple...
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Dietary habits, nutritional status and risk of a first demyelinating event: an incident case-control study in a southern European cohort
BackgroundThe relationship between dietary habits and multiple sclerosis (MS) risk is still controversial. Most studies have involved populations...
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Effect of Omega-3 fatty acid supplementation on sexual function of pregnant women: a double blind randomized controlled trial
AbstractThe aim of this study was to evaluate the effect of omega-3 fatty acid supplementation on female sexual function during pregnancy. The...
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Effect of essential fatty acid blend on circadian variations of ambulatory blood pressure in patients with essential hypertension and coronary artery disease risk markers
Flaxseed oil is an excellent source of alpha-linolenic acid ALA known for its antihypertensive action. Flaxseed oil is unstable and its dose is not...
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Changes in fatty acid levels (saturated, monounsaturated and polyunsaturated) during pregnancy
BackgroundDuring pregnancy a high amount of fatty acids (FA) is necessary to meet foetus demands, which vary during gestation. The present study...
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Network pharmacology combined with metabolomics to explore the mechanism for Lonicerae Japonicae flos against respiratory syncytial virus
BackgroundRespiratory Syncytial Virus (RSV) stands out as a primary contributor to lower respiratory tract infections and hospitalizations,...
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Impact of fish oil supplementation on plasma levels of highly unsaturated fatty acid-containing lipid classes and molecular species in American football athletes
BackgroundPrevious studies have linked sports-related concussions and repeated subconcussive head impacts in contact sport athletes to elevated brain...
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Investigation into the protective effects of hypaconitine and glycyrrhetinic acid against chronic heart failure of the rats
BackgroundThe present study aimed to determine the protective effects of hypaconitine (HA) and glycyrrhetinic acid (GA) against chronic heart failure...
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Fatty acid composition but not quantity is an important indicator of non-alcoholic fatty liver disease: a systematic review
BackgroundThere is still paucity on the effects of dietary and supplemental fatty acid on non-alcoholic fatty liver disease (NAFLD). The aim of this...
