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Serum inflammation markers associated with altered brain white matter microstructure in people with HIV on antiretroviral treatment
BackgroundMany studies have reported reduced brain white matter fractional anisotropy (FA) and increased mean diffusivity (MD) on diffusion tensor...
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Prenatal exposure to maternal disadvantage-related inflammatory biomarkers: associations with neonatal white matter microstructure
Prenatal exposure to heightened maternal inflammation has been associated with adverse neurodevelopmental outcomes, including atypical brain...
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Serum albumin and white matter hyperintensities
People living with HIV and those diagnosed with alcohol use disorders (AUD) relative to healthy individuals commonly have low levels of serum...
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NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance
Encephalitis has an estimated prevalence of ≤0.01%. Even with extensive diagnostic work-up, an infectious etiology is identified or suspected in <50%...
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Subclinical Metabolic and Cardiovascular Factors and Brain White Matter Microstructural Integrity in Young Women
Women who have experienced pregnancy complications, specifically preeclampsia and gestational diabetes, have well documented increased risks of...
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Changes in kynurenine metabolites in the gray and white matter of the dorsolateral prefrontal cortex of individuals affected by schizophrenia
Alterations in the kynurenine pathway of tryptophan metabolism have been implicated in the pathophysiology of schizophrenia. Here, we performed an...
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Sex-specific inflammatory and white matter effects of prenatal opioid exposure: a pilot study
BackgroundPreclinical data demonstrate that opioids modulate brain reward signaling through an inflammatory cascade, but this relationship has yet to...
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Evaluation of brain white matter changes on MRI in patients newly diagnosed with obstructive sleep apnea compared with the control group
BackgroundObstructive sleep apnea (OSA) is nowadays introduced as a risk factor for white matter brain changes. Research on OSA and white matter...
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Interactions between overweight/obesity and alcohol dependence impact human brain white matter microstructure: evidence from DTI
There is inconsistent evidence for an association of obesity with white matter microstructural alterations. Such inconsistent findings may be related...
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Rectal temperature after hypoxia-ischemia predicts white matter and cortical pathology in the near-term ferret
BackgroundNeonatal encephalopathy (NE) remains a common cause of infant morbidity and mortality. Neuropathological corollaries of NE associated with...
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Micro-structural white matter abnormalities in new daily persistent headache: a DTI study using TBSS analysis
BackgroundNew daily persistent headache (NDPH) is a rare primary headache disorder characterized by daily and persistent sudden onset headaches. The...
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Cortico-basal ganglia white matter microstructure is linked to restricted repetitive behavior in autism spectrum disorder
BackgroundRestricted repetitive behavior (RRB) is one of two behavioral domains required for the diagnosis of autism spectrum disorder (ASD)....
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The influence of nutrition on white matter development in preterm infants: a sco** review
AbstractWhite matter (WM) injury is the most common type of brain injury in preterm infants and is associated with impaired neurodevelopmental...
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The associations between peripheral inflammatory and lipid parameters, white matter hyperintensity, and cognitive function in patients with non-disabling ischemic cerebrovascular events
BackgroundThe global prevalence of VCI has increased steadily in recent years, but diagnostic biomarkers for VCI in patients with non-disabling...
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Association of smoking with brain gray and white matter volume: a Mendelian randomization study
BackgroundObservational studies have found a significant association between smoking and smaller gray matter volume, but this finding was limited by...
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Characterizing the penumbras of white matter hyperintensities in patients with cerebral small vessel disease
PurposeThe white matter hyperintensity penumbra (WMH-P) is the subtly changed normal-appearing white matter (NAWM) that surrounds white matter...
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Microglia activation in periplaque white matter in multiple sclerosis depends on age and lesion type, but does not correlate with oligodendroglial loss
Multiple sclerosis (MS) is the most frequent inflammatory and demyelinating disease of the CNS. The disease course in MS is highly variable and...
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Magnetic resonance imaging of disorders with white matter changes in children and adolescents: a pictorial essay
White matter changes are seen in a spectrum of disorders in children and adolescents. Understanding their distribution and appearance helps to reach...
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Regional white matter and gray matter damage and cognitive performances in multiple sclerosis according to sex
In this study, we investigated whether regional distribution of white matter (WM) lesions, normal-appearing [NA] WM microstructural abnormalities and...
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Is coronary artery calcium an independent risk factor for white matter hyperintensity?
BackgroundCardiovascular diseases have been considered the primary cause of disability and death worldwide. Coronary artery calcium (CAC) is an...