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Comparative study of weekly and three-weekly neoadjuvant carboplatin in triple-negative breast cancer: retrospective analysis in real-world settings
PurposeTri-weekly carboplatin is an established neoadjuvant treatment for triple-negative breast cancer, enhancing pathological complete response...
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Twice-Weekly Versus Once-Weekly Membrane Swee** in the Prevention of Post-Term Pregnancy: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Membrane swee** is considered a simple and effective method for initiating spontaneous onset of labor. Despite the widely accepted membrane...
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Twice weekly dosing with Sebelipase alfa (Kanuma®) rescues severely ill infants with Wolman disease
BackgroundSebelipase alfa (Kanuma®) is approved for patients with Wolman disease (WD) at a dosage of 3–5 mg/kg once weekly. Survival rates in the...
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Weekly versus triweekly cisplatin treatment in patients with locally advanced nasopharyngeal cancer during concurrent chemoradiotherapy
BackgroundFor patients with locally advanced nasopharyngeal cancer (LA-NPC), concurrent chemoradiotherapy (CCRT) is the standardized treatment....
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Once-weekly insulins: a promising approach to reduce the treatment burden in people with diabetes
Despite the availability of new classes of glucose-lowering drugs that improve glycaemic levels and minimise long-term complications, at least 20–25%...
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Patient-reported outcomes in a pilot clinical trial of twice-weekly hemodialysis start with adjuvant pharmacotherapy and transition to thrice-weekly hemodialysis vs conventional hemodialysis
BackgroundPhysical and emotional symptoms are prevalent in patients with kidney-dysfunction requiring dialysis (KDRD) and the rigors of thrice-weekly...
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The long-term cost-effectiveness of once-weekly semaglutide versus sitagliptin for the treatment of type 2 diabetes in China
BackgroundTo estimate the long-term cost-effectiveness of once-weekly semaglutide versus sitagliptin as an add-on therapy for type 2 diabetes...
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Do sociodemographic risk profiles for adolescents engaging in weekly e-cigarette, cigarette, and dual product use differ?
BackgroundE-cigarette use represents a contemporary mode of nicotine product use that may be changing the risk profile of participating adolescents....
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Efficacy and Safety of Once-Weekly Insulin Regimes on Glycemic Control for Type 2 Diabetes: A Systematic Review and Network Meta-analysis
BackgroundRandomized controlled trials have found that once-weekly insulin resulted in greater glycemic control compared to once-daily insulin in...
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Treatment outcomes of radiotherapy with concurrent weekly cisplatin in older patients with locally advanced head and neck squamous cell carcinoma
BackgroundTri-weekly cisplatin and radiotherapy (CDDP + RT) is a standard of care for locally advanced head and neck squamous cell carcinoma...
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Impact of thrice-weekly cotrimoxazole prophylaxis on creatinine and potassium plasma levels in kidney transplant recipients
IntroductionCotrimoxazole (CTX) 800/160 mg daily or thrice-weekly is recommended as prophylaxis of Pneumocystis jirovecii pneumonia in kidney...
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Timeliness and completeness of weekly surveillance data reporting on epidemic prone diseases in Uganda, 2020–2021
IntroductionDisease surveillance provides vital data for disease prevention and control programs. Incomplete and untimely data are common challenges...
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Twice or thrice weekly levothyroxine provides similar rates of adherence and post-Ramadan euthyroidism compared to daily levothyroxine during Ramadan fasting
BackgroundHaving to take levothyroxine (L-T4) on a daily basis, on an empty stomach is burdensome and may impair adherence, especially during Ramadan...
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Efficacy of Self-Review of Lifestyle Behaviors with Once-Weekly Glycated Albumin Measurement in People with Type 2 Diabetes: A Randomized Pilot Study
IntroductionLifestyle management, including appropriate modifications of nutrition, exercise, and medication behaviors, is essential for optimal...
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Weekly minutes of moderate to vigorous physical activity is associated with movement quality in overweight and obese older adults, independent of age
BackgroundPhysical activity can improve function and decrease healthcare spending among overweight and obese older adults. Although unstructured...
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Glycemic Control and Body Weight Reduction with Once-Weekly Semaglutide in Colombian Adults with Type 2 Diabetes: Findings from the COLIBRI Study
IntroductionType 2 diabetes is a prevalent condition. The change in glucose control and body weight with the use of once-weekly semaglutide was...
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A propensity score–weighted study comparing a two- versus four-weekly pegylated liposomal doxorubicin regimen in metastatic breast cancer
PurposeA 4-weekly schedule of pegylated liposomal doxorubicin (PLD) has been approved for the treatment of metastatic breast cancer (MBC). Phase II...
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Safety and Preliminary Efficacy of Once-Weekly Split-Dose Selinexor in Soft Tissue Sarcoma: Results of the Phase Ib METSSAR Clinical Trial
BackgroundThe approved dose of Selinexor, 60 mg twice-weekly, is associated with several clinically relevant toxicities. Preclinical studies show...
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Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report
BackgroundSingle-time non-invasive brain stimulation was carried out using the two-technique approach on a patient suffering from treatment-resistant...
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Multicenter prospective phase II trial of concurrent chemoradiotherapy with weekly low-dose carboplatin for cisplatin-ineligible patients with advanced head and neck squamous cell carcinoma
BackgroundThe optimal chemotherapy regimen in concurrent chemoradiotherapy (CCRT) for cisplatin-ineligible head and neck squamous cell carcinoma...
