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Individual response in patient’s effort and driving pressure to variations in assistance during pressure support ventilation
BackgroundDuring Pressure Support Ventilation (PSV) an inspiratory hold allows to measure plateau pressure (Pplat), driving pressure (∆P),...
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Higher baseline heart rate variability in CCHS patients with progestin-associated recovery of hypercapnic ventilatory response
After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took...
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Total face mask with neurally adjusted ventilatory assist as a rescue therapy in infants with severe bronchiolitis
AbstractSevere bronchiolitis patients are often supported with non-invasive ventilation (NIV). In case of NIV failure, we recently started to use...
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The Diaphragmatic Initiated Ventilatory Assist (DIVA) trial: study protocol for a randomized controlled trial comparing rates of extubation failure in extremely premature infants undergoing extubation to non-invasive neurally adjusted ventilatory assist versus non-synchronized nasal intermittent positive pressure ventilation
BackgroundInvasive mechanical ventilation contributes to bronchopulmonary dysplasia (BPD), the most common complication of prematurity and the...
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Effects of Varying Levels of Inspiratory Assistance with Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist on Driving Pressure in Patients Recovering from Hypoxemic Respiratory Failure
BackgroundDriving pressure can be readily measured during assisted modes of ventilation such as pressure support ventilation (PSV) and neurally...
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Non-invasive ventilation in neuromuscular diseases: should we use higher levels of ventilatory support?
PurposeIn patients with COPD, one of the leading indications for domiciliary non-invasive ventilation (NIV), a major paradigm shift has been observed...
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Study protocol for a randomised cross-over trial of Neurally adjusted ventilatory Assist for Neonates with Congenital diaphragmatic hernias: the NAN-C study
BackgroundNeurally adjusted ventilatory assist (NAVA) is a mode of mechanical ventilation that delivers oxygen pressures in proportion to electrical...
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The predictive value of neurally adjusted ventilatory assist indexes for the prognosis of patients with severe cerebral hemorrhage
ObjectiveThis study assessed the predictive value of electrical activity of the diaphragm (EAdi) and the EAdi-derived monitoring index in the...
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Comparison of neurally adjusted ventilatory assist and synchronized intermittent mandatory ventilation in preterm infants after patent ductus arteriosus ligation: a retrospective study
ObjectiveThis study aimed to compare the efficacy of neurally adjusted ventilatory assist (NAVA) to synchronized intermittent mandatory ventilation...
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Development and assessment of the performance of a shared ventilatory system that uses clinically available components to individualize tidal volumes
ObjectivesTo develop and assess a system for shared ventilation using clinically available components to individualize tidal volumes.
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Neurally adjusted ventilatory assist as a weaning mode for adults with invasive mechanical ventilation: a systematic review and meta-analysis
BackgroundProlonged ventilatory support is associated with poor clinical outcomes. Partial support modes, especially pressure support ventilation,...
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Continuous assessment of neuro-ventilatory drive during 12 h of pressure support ventilation in critically ill patients
IntroductionPressure support ventilation (PSV) should allow spontaneous breathing with a “normal” neuro-ventilatory drive. Low neuro-ventilatory...
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The use of head helmets to deliver noninvasive ventilatory support: a comprehensive review of technical aspects and clinical findings
A helmet, comprising a transparent hood and a soft collar, surrounding the patient’s head can be used to deliver noninvasive ventilatory support,...
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Implementation of noninvasive neurally adjusted ventilatory assist in pediatric acute respiratory failure: a controlled before-after quality improvement study
BackgroundsPediatric noninvasive neurally adjusted ventilatory assist (NIV-NAVA) has been shown to improve patient-ventilator interaction but no data...
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Ventilatory management of patients on ECMO
Extracorporeal membrane oxygenation (ECMO) is the final treatment offered to patients of acute respiratory distress syndrome (ARDS). The survival (to...
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Pendelluft in hypoxemic patients resuming spontaneous breathing: proportional modes versus pressure support ventilation
BackgroundInternal redistribution of gas, referred to as pendelluft, is a new potential mechanism of effort-dependent lung injury. Neurally-adjusted...
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Neurally adjusted ventilatory assist in acute respiratory failure: a randomized controlled trial
PurposeWe hypothesized that neurally adjusted ventilatory assist (NAVA) compared to conventional lung-protective mechanical ventilation (MV)...
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Congenital laryngo-tracheo-esophageal clefts: updates from a quaternary care pediatric airway unit
PurposeTo review the operative techniques, outcomes, and complications following surgery in pediatric patients with laryngo-tracheo-esophageal clefts...
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Ventilatory Response at Rest and During Maximal Exercise Testing in Patients with Severe Obesity Before and After Sleeve Gastrectomy
IntroductionSleeve gastrectomy (SG) has become a widespread treatment option in patients affected by severe obesity. However, studies investigating...
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Impact of corticosteroids on the duration of ventilatory support during severe acute exacerbations of chronic obstructive pulmonary disease in patients in the intensive care unit: a study protocol for a multicentre, randomized, placebo-controlled, double-blind trial
BackgroundPatients who are admitted to the intensive care unit (ICU) for severe acute exacerbations of chronic obstructive pulmonary disease (COPD)...
