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Intratumoral metastasis of sigmoid colon cancer to chromophobe renal cell carcinoma: a case report
We herein report an extremely rare case of intratumoral metastasis of colon cancer to chromophobe renal cell carcinoma. A 71-year-old woman was...
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Impact of cavity shaving on residual tumor rates in patients with primary invasive carcinoma and carcinoma in situ in breast conserving surgery
BackgroundSeveral international studies reported relatively high re-excision rates due to residual tumor in breast conserving surgery (BCS). Cavity...
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Verruciform Xanthoma: Clinical and Morphologic Spectrum Across Oral, Genital, and Cutaneous Sites
BackgroundVerruciform xanthoma (VX) is an uncommon, benign epithelial lesion of the oral mucosa. While this entity can also present extraorally,...
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To characterize small renal cell carcinoma using diffusion relaxation correlation spectroscopic imaging and apparent diffusion coefficient based histogram analysis: a preliminary study
PurposeTo study the capability of diffusion-relaxation correlation spectroscopic imaging (DR-CSI) on subtype classification and grade differentiation...
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A programmed cell death-related gene signature to predict prognosis and therapeutic responses in liver hepatocellular carcinoma
BackgroundProgrammed cell death (PCD) functions critically in cancers and PCD-related genes are associated with tumor microenvironment (TME),...
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Evaluation of anaplastic thyroid carcinoma in the Kurdistan region of Iraq
BackgroundAnaplastic thyroid carcinoma is a rare and lethal disease that accounts for 1–2% of thyroid malignancies. It is an aggressive locoregional...
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Clinical impact of myosteatosis measured by magnetic resonance imaging on long-term outcomes of hepatocellular carcinoma after radical hepatectomy
AimsA variety of factors have been reported to affect long-term outcomes after radical resection of hepatocellular carcinoma (HCC). However, the...
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The ATR inhibitor berzosertib acts as a radio- and chemosensitizer in head and neck squamous cell carcinoma cell lines
Alterations in the DNA damage response play a crucial role in radio- and chemoresistance of neoplastic cells. Activation of the Ataxia telangiectasia...
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Comparison of the 7th and revised 8th UICC editions (2020) for oral squamous cell carcinoma: How does the reclassification impact staging and survival?
Since its introduction in 1968, the TNM (tumor, node, metastasis) classification established by the International Union Against Cancer has provided a...
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Clinical and Dosimetric Predictors for Postoperative Cardiopulmonary Complications in Esophageal Squamous Cell Carcinoma Patients Receiving Neoadjuvant Chemoradiotherapy and Surgery
BackgroundNeoadjuvant chemoradiotherapy followed by esophagectomy is the standard treatment for patients with locally advanced esophageal squamous...
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Four-dimensional flow MR imaging for evaluating treatment response after transcatheter arterial chemoembolization in cirrhotic patients with hepatocellular carcinoma
PurposeTo prospectively evaluate the potential of four-dimensional (4D) flow magnetic resonance imaging (MRI) in predicting treatment responses after...
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Chemoradiotherapy for fistula-related perianal squamous cell carcinoma with Crohn’s disease
The reports of chemoradiotherapy for anal squamous cell carcinoma with Crohn’s disease are few. Severe toxicity related to radiotherapy is concerned...
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The routine use of LCD-Array hybridisation technique for HPV subty** in the diagnosis of penile carcinoma compared to other methods
BackgroundRoutine human papillomavirus (HPV) testing is performed in cervival cancer and is required for classification of some head and neck...
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Oxygen Imaging of a Rabbit Tumor Using a Human-Sized Pulse Electron Paramagnetic Resonance Imager
PurposeSpatial heterogeneity in tumor hypoxia is one of the most important factors regulating tumor growth, development, aggressiveness, metastasis,...
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Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors
Non-keratinizing nasopharyngeal carcinoma (NPC) is a malignancy with a poor prognosis for relapsing patients and those with metastatic disease. Here,...
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Modeling the risk of radiation pneumonitis in esophageal squamous cell carcinoma treated with definitive chemoradiotherapy
BackgroundTo develop and validate a nomogram for the prediction of symptomatic radiation pneumonitis (RP) in patients with esophageal squamous cell...
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Texture analysis of [18F]-fluorodeoxyglucose-positron emission tomography/computed tomography for predicting the treatment response of postoperative recurrent or metastatic oral squamous cell carcinoma treated with cetuximab
ObjectiveTo assess the value of the texture analysis of fluorine- 18 F-fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 F-FDG-PET...
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Definitive chemoradiotherapy for a patient with anal cancer after renal transplantation
Patients after renal transplantation are susceptible to secondary malignancies, including anal squamous cell carcinoma. Chemoradiotherapy is the...
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18F-FDG texture analysis predicts the pathological Fuhrman nuclear grade of clear cell renal cell carcinoma
PurposeThis article analyzes the image heterogeneity of clear cell renal cell carcinoma (ccRCC) based on positron emission tomography (PET) and...
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Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice
BackgroundThe Ataxia Telangiectasia and Rad3-related (ATR) protein complex is an apical initiator of DNA damage response pathways. Several ATR...