Search
Search Results
-
Role of Soluble Urokinase-Type Plasminogen Activator Receptor in Cardiovascular Disease
Purpose of ReviewChronic inflammation is a major contributor to cardiovascular disease (CVD) risk. Soluble urokinase plasminogen activator receptor...
-
Soluble urokinase plasminogen activator receptor (suPAR) in children with obesity or type 1 diabetes as a marker of endothelial dysfunction: a cross-sectional study
Pediatric obesity and type 1 diabetes mellitus (T1DM) represent two common chronic diseases associated with chronic inflammation, endothelial...
-
Soluble urokinase plasminogen activator receptor and cardiotoxicity in doxorubicin-treated breast cancer patients: a prospective exploratory study
BackgroundSoluble urokinase plasminogen activator receptor is an inflammatory biomarker that may prognosticate cardiovascular outcomes. We sought to...
-
Urokinase-Type Plasminogen Activator Receptor (uPAR) Expression and [64Cu]Cu-DOTA-AE105 uPAR-PET/CT in Patient-Derived Xenograft Models of Oral Squamous Cell Carcinoma
Purpose[ 64 Cu]Cu-DOTA-AE105 urokinase-type plasminogen activator receptor (uPAR)-PET/CT is a novel and promising imaging modality for cancer...
-
Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship
Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells...
-
Soluble urokinase plasminogen activator receptor (suPAR) in bronchoalveolar fluid and blood in critically ill patients—a prospective cohort study
IntroductionSoluble urokinase plasminogen activator receptor (suPAR) is a biologically active protein and increased levels are associated with worse...
-
Plasminogen activator inhibitor-1 levels in prior gestational diabetes mellitus: A systematic review and meta-analysis
ObjectiveConflicting results on the association of plasminogen activator inhibitor-1 (PAI-1) with prior gestational diabetes mellitus ( p GDM) have...
-
Soluble urokinase plasminogen activator receptor in vaginally collected amniotic fluid predicting fetal inflammatory response syndrome: a prospective cohort study
BackgroundImproving noninvasive antenatal diagnosis of fetal inflammatory response syndrome (FIRS) can assist in the evaluation of prenatal risk and...
-
Plasminogen activator inhibitor-1 is involved in glucocorticoid-induced decreases in angiogenesis during bone repair in mice
IntroductionGlucocorticoids delay fracture healing and induce osteoporosis. Angiogenesis plays an important role in bone repair after bone injury....
-
Plasminogen activator inhibitor-1 genotype 4G/5G associates with skin involvement in Armenian familial Mediterranean fever patients
There is little and conflicting data on the role of the plasminogen activator inhibitor-1 ( PAI-1 , SERPINE1 ) 4G/5G polymorphism in familial...
-
Enhanced Expression of Plasminogen Activators and Inhibitor in the Healing of Tympanic Membrane Perforation in Rats
The significance of plasminogen activation during the tympanic membrane (TM) healing is known mainly from studies performed on knock-out mice. In the...
-
The Plasminogen Activator System, Glucocorticoid, and Mineralocorticoid Receptors in the Primate Endometrium During Artificial Menstrual Cycles
As a key mechanism in fibrinolysis and tissue remodeling, the plasminogen activator system has been suggested in the process of endometrial shedding...
-
Serum levels of soluble urokinase plasminogen activator receptor in juvenile idiopathic arthritis: a single-center Swedish case-control study
ObjectivesReliable biomarkers in the early stages of idiopathic arthritis (JIA) are scarce and the disease heterogeneity makes it clinically...
-
Soluble urokinase plasminogen activator receptor is associated with cardiovascular calcification in peritoneal dialysis patients
BackgroundCardiovascular disease (CVD) is an important cause of morbidity and mortality in peritoneal dialysis (PD) patients. Cardiovascular...
-
Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms
BackgroundThere is evidence of increased low grade inflammation (LGI) in schizophrenia patients. However, the inter-individual variation is large and...
-
Dysregulated hemostasis in acute promyelocytic leukemia
Acute promyelocytic leukemia (APL) is associated with a high incidence of early death, which occurs within 30 days of diagnosis. The major cause of...
-
Soluble urokinase plasminogen activator receptor is associated with short-term mortality and enhanced reactive oxygen species production in acute-on-chronic liver failure
BackgroundAcute-on-chronic liver failure (ACLF) is a comprehensive syndrome characterized by an acute deterioration of liver function and high...
-
Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR)
PurposeCervical cancer metastasis results in poor prognosis and increased mortality, which is not separated from inflammatory reactions accumulated...
-
The Role of Coagulation in Heart Failure: A Literature Review
Purpose of ReviewThis article summarizes the role of coagulation factors in the pathophysiology of heart failure including D-dimer, fibrinogen and...
-
Expression of urokinase-type plasminogen activator system in non-metastatic prostate cancer
PurposeTo investigate the prognostic role of expression of urokinase-type plasminogen activator system members, such as urokinase-type activator...
