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Storing urine samples with moisture preserves urine hydration marker stability up to 21 days
IntroductionTo assess hydration status, hydration markers [urine color, osmolality, and urine-specific gravity (USG)] are used. Urine color,...
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The association of urine osmolality with decreased kidney function and/or albuminuria in the United States
BackgroundDecreased kidney function is commonly caused by hypovolemia. When hypovolemic, the kidney reabsorbs water resulting in concentrated urine....
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Detection of low urine output by measuring urinary biomarkers
BackgroundUrine output < 1 L per 24 h is a clinical warning sign that requires attention from hospital staff, who should determine whether the low...
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Urine osmolality predicts calcium-oxalate crystallization risk in patients with recurrent urolithiasis
Our aim was to investigate the validity of osmolality from 24-h urine collection in examining the risk for calcium-oxalate (CaOx) kidney stone...
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Identifying the main predictors of urine output in autosomal-dominant polycystic kidney disease (ADPKD) patients taking tolvaptan
BackgroundFew works have analyzed factors associated with urine output in ADPKD patients taking tolvaptan (TVP).
MethodsWe selected 24-h urine...
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The U-shaped association between serum osmolality and 28-day mortality in patients with sepsis: a retrospective cohort study
BackgroundSepsis is a recognized global health challenge that places a considerable disease burden on countries. Although there has been some...
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Serum osmolality and hyperosmolar states
Serum osmolality is the sum of the osmolalities of every single dissolved particle in the blood such as sodium and associated anions, potassium,...
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Quantifying the daily intake of water from morning and spot urine samples; retrospective analysis of a clinical trial in volunteers
BackgroundThe hydration status can be indicated by biomarkers in the urine. However, the sensitivity and specificity of single measurements of...
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Pretreatment morning urine osmolality and oral desmopressin lyophilisate treatment outcome in patients with primary monosymptomatic enuresis
PurposeTo determine the association between urine osmolality (Uosm) in patients with primary monosymptomatic enuresis (PMNE) and response to...
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Urine Specific Gravity Measurement for Fluid Balance in Neonates on Intravenous Fluids in a Neonatal Intensive Care Unit: An Open Label Randomized Controlled Trial
BackgroundUrine specific gravity reflects hydration status and correlates well with urine osmolality.
ObjectiveTo compare intravenous fluid therapy...
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Prognostic impact of urine cyclic AMP levels in patients with chronic kidney disease
BackgroundUrine cyclic adenosine monophosphate (cAMP) is a biomarker to assess the residual function of the collecting duct in the kidney. Prognostic...
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Impact of urine cyclic AMP relative to plasma arginine vasopressin on response to tolvaptan in patients with chronic kidney disease and heart failure
BackgroundThe clinical utility of tolvaptan in chronic kidney disease (CKD) patients with heart failure remains uncertain. The level of urine cyclic...
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Long-term health outcomes associated with hydration status
Body water balance is determined by fundamental homeostatic mechanisms that maintain stable volume, osmolality and the composition of extracellular...
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Combining urine color and void number to assess hydration in adults and children
Background/objectivesTo test the diagnostic ability of two combined practical markers for elevated urine osmolality (underhydration) in free-living...
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Prognostic relevance of elevated plasma osmolality on admission in acute decompensated heart failure with preserved ejection fraction: insights from PURSUIT-HFpEF registry
BackgroundComplicated pathophysiology makes it difficult to identify the prognosis of heart failure with preserved ejection fraction (HFpEF). While...
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Online Arabic Beverage Frequency Questionnaire (ABFQ): evaluation of validity and reliability
BackgroundObesity and chronic diseases are significant public health issues in the Middle East and North Africa region. A robust body of evidence...
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Alteration of the maximal renal water excretion capacity with kidney function and age in human
PurposeThe kidney’s capability to concentrate and dilute urine is crucial to maintaining body fluid compartments and plasma osmolality. Advanced age...
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Afternoon urine osmolality is equivalent to 24 h for hydration assessment in healthy children
Background/ObjectivesWhile daily hydration is best assessed in 24-h urine sample, spot sample is often used by health care professionals and...
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Altered arginine vasopressin-cyclic AMP-aquaporin 2 pathway in patients with chronic kidney disease
BackgroundIn the collecting ducts of the kidney, arginine vasopressin (AVP), cyclic adenosine monophosphate (cAMP), and aquaporin 2 (AQP2) play a...
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Urine neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury and prognosis in decompensated chronic liver disease: A prospective study
BackgroundAcute kidney injury (AKI) heralds deterioration in patients with decompensated chronic liver disease (DCLD). Serum creatinine (sCr), a...