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Timing to Surgery and Lymph Node Upstaging in Gastric Cancer: An NCDB Analysis
BackgroundPrior studies have shown tumor specificity on the impact of longer time interval from diagnosis to surgery, however in gastric cancer (GC)...
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Development and internal validation of a nomogram predicting 3-year chronic kidney disease upstaging following robot-assisted partial nephrectomy
PurposeAim of the present study was to develop and validate a nomogram to accurately predict the risk of chronic kidney disease (CKD) upstaging at...
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Nomogram for predicting axillary upstaging in clinical node-negative breast cancer patients receiving neoadjuvant chemotherapy
PurposeThe prediction of axillary lymph node status after neoadjuvant chemotherapy (NAC) becoming critical because of the advocation of the...
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Adverse upgrading and/or upstaging in contemporary low-risk prostate cancer patients
BackgroundUpgrading and/or upstaging in low-risk prostate cancer (PCa) patients may represent an indication for active treatment instead of active...
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High rate of postoperative upstaging of ductal carcinoma in situ when prioritizing ultrasound evaluation of mammography-detected lesions: a single-center retrospective cohort study
BackgroundThe initial diagnosis of ductal carcinoma in situ (DCIS) can be upstaged to invasive cancer after definitive surgery. This study aimed to...
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Validation and Clinical Utility of a Prediction Model for the Risk of Upstaging to Invasive Breast Cancer After a Biopsy Diagnosis Ductal Carcinoma In Situ
BackgroundThis study aimed to validate the DCIS-upstage model, a previously developed model to predict the risk of upstaging to invasive breast...
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Number of lymph nodes dissected and upstaging rate of the N factor in robot-assisted thoracic surgery versus video-assisted thoracic surgery for patients with cN0 primary lung cancer
PurposeThe accuracy of lymph node (LN) dissection in robotic surgery for lung cancer remains controversial. We compared the accuracy of LN dissection...
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Prolonged Time from Diagnosis to Breast-Conserving Surgery is Associated with Upstaging in Hormone Receptor-Positive Invasive Ductal Breast Carcinoma
BackgroundTime to surgery (TTS) has been suggested to have an association with mortality in early-stage breast cancer.
ObjectiveThis study aims to...
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The impact of race/ethnicity on upstaging and/or upgrading rates among intermediate risk prostate cancer patients treated with radical prostatectomy
BackgroundRace/ethnicity may predispose to less favorable prostate cancer characteristics in intermediate risk prostate cancer (IR PCa) patients. We...
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Endogenous testosterone density associates with predictors of tumor upgrading and disease progression in the low through favorable intermediate prostate cancer risk categories: analysis of risk factors and clinical implications
BackgroundThe study aimed to test the hypothesis that endogenous testosterone density (ETD), in the low through favorable intermediate PCa risk...
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Wilms’ tumor in low- and middle-income countries: survey of current practices, challenges, and priorities
PurposeTo identify the current practices and priorities in Wilms’ tumor management for surgeons in low- and middle-income countries (LMICs).
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Clinicopathological predictors of postoperative upstaging to invasive ductal carcinoma (IDC) in patients preoperatively diagnosed with ductal carcinoma in situ (DCIS): a multi-institutional retrospective cohort study
BackgroundWe conducted a prospective study with the intention to omit surgery for patients with ductal carcinoma in situ (DCIS) of the breast. We...
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Upstaging of basal cell and squamous cell carcinomas during definitive surgery: a review of predictive preoperative clinical and histologic features
The incidence of nonmelanoma skin cancer (NMSC) in the United States is increasing with approximately 3.6 million cases diagnosed per year. The...
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Reappraising the clinical usability of consolidation-to-tumor ratio on CT in clinical stage IA lung cancer
ObjectivesGround-glass opacity (GGO) on computed tomography is associated with prognosis in early-stage non-small cell lung cancer (NSCLC) patients....
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Staged melanoma excision requires larger margins for tumor clearance and results in low rates of recurrence
There is controversy regarding the optimal surgical modality and ideal recommended margins for treating melanoma in situ (MIS) and invasive melanoma...
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Squamous cell carcinoma in situ upstaging is not frequent in the nail unit: a tertiary cancer center experience
Squamous cell carcinoma in situ (SCCIS) of the nail unit is a complex malignancy; with little understanding of rate of upstaging or occult invasion...
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Need for adjuvant radiotherapy in oral cancer: depth of invasion rather than tumor diameter
PurposeThe 8th edition of the TNM Cancer Staging Manual incorporates depth of invasion (DOI) into the pathologic tumor classification for oral...
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Comparison of the 7th and revised 8th UICC editions (2020) for oral squamous cell carcinoma: How does the reclassification impact staging and survival?
Since its introduction in 1968, the TNM (tumor, node, metastasis) classification established by the International Union Against Cancer has provided a...
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Impact of Lymph Node Dissection on Survival and Tumor Recurrence for Patients with Resected cT1-2N0 Small Cell Lung Cancer
BackgroundThe role of lymph node (LN) dissection for early-stage small cell lung cancer (SCLC) remains unclear. Therefore, this study aimed to...
