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True hermaphroditism with sex cord tumor with annular tubules (SCTAT): a rare case report and review of the literature
BackgroundTrue hermaphroditism is a rare condition. It is defined as the presence of both testicular and ovarian tissues in the same individual. Sex...
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RSPO1-mutated fibroblasts from non-tumoural areas of palmoplantar keratoderma display a cancer-associated phenotype
BackgroundR-spondin (RSPO)1 is a fibroblast-secreted protein that belongs to the R-spondin protein family which is essential for reproductive organ...
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Poseidon and Caeneus: a case of pubertal gender inversion in Greek mythology
Disorders of sex development (DSDs) are very frequently encountered in ancient Greek mythology. One of the most striking types of DSD described in...
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Male pseudohermaphroditism in a complex malformed calf born with an acardius amorphus cotwin—a case report
BackgroundMale pseudohermaphroditism is a developmental anomaly wherein animals are genetically and gonadally male, but their internal and/or...
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A rare congenital anomaly in a female child with acute urinary retention—female hypospadias: a case report
BackgroundFemale hypospadias is a rare congenital anomaly and defined as a female urethral opening on the anterior vaginal wall. Diagnosis is...
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Transverse testicular ectopia with inguinal hernia in an adult—a case report
BackgroundTransverse testicular ectopia (TTE) is a rare congenital anomaly in which both the testis are in the same hemiscrotum or one testis in the...
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The use of eponyms in medical case reports: etymological, quantitative, and structural analysis
BackgroundThe present paper focuses on eponyms, that is, terms with proper names, in particular, derived from world mythologies, the Bible, and...
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Disorders of sexual development: structured radiological reporting and practical approach
Disorders of sexual development (DSD) comprise a complex group of conditions with varied clinical presentations, such as atypical genitalia,...
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Endocrine disruptors in ancient times and Greek mythology: the spring of Salmacis and the curse of Hermaphroditus
According to Greek mythology, the spring waters of Salmacis (or Salmakis) feminized the god Hermaphroditus (or Hermaphroditos) and transformed his...
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Management of Gender Determination of Newborns and Children with Disorders of Sex Development Using a Multidisciplinary Approach: An Exploratory Study of Islamic Perspective in Malaysia
Management of newborns with disorders of sex development (DSD), especially in deciding the need for a sex assignment surgery, is a complex matter. It...
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A review of the essential concepts in diagnosis, therapy, and gender assignment in disorders of sexual development
BackgroundThe aim of this article is to review the essential concepts, current terminologies and classification, management guidelines and the...
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Management of high inguinal undescended testis: a review of literature
BackgroundUndescended testis is one of the most common paediatric surgical diagnoses. A lot of research has been done to date, to standardise the...
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Symptomatic prostatic utricle: various approaches for treatment
BackgroundPediatric presentations of a prostatic utricle have received only little attention. The incidence of symptomatic prostatic utricle has been...
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Prevalence of coat colour traits and congenital disorders of South American camelids in Austria, Germany and Switzerland
BackgroundThe increasing popularity of alpacas and llamas outside of South America is undeniable. The associated limited genetic diversity raises...
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The (Un)Ethical Womb: The Promises and Perils of Artificial Gestation
The purpose of this article is to reflect on the changes that the implementation of artificial wombs would bring to society, the family, and the...
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Ignaz Semmelweis: a victim of harassment?
Ignaz Semmelweis’ (1818–1865) discovery of the endemic causes of febris puerperalis is a striking example of the role of pathology in medicine....
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Analytical Review of Contemporary Fatwas in Resolving Biomedical Issues Over Gender Ambiguity
Issues of gender ambiguity have been discussed over time from both Islamic and medical perspectives. In Islam, these issues are typically considered...
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Genes predisposing to syndromic and nonsyndromic infertility: a narrative review
BackgroundAdvanced biological techniques have helped produce more insightful findings on the genetic etiology of infertility that may lead to better...