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  1. Pharmacological modulation of adaptive thermogenesis: new clues for obesity management?

    Background

    Adaptive thermogenesis represents the main mechanism through which the body generates heat in response to external stimuli, a phenomenon...

    V. A. Genchi, G. Palma, ... S. Perrini in Journal of Endocrinological Investigation
    Article Open access 28 June 2023

  2. Genetic evidence for involvement of β2-adrenergic receptor in brown adipose tissue thermogenesis in humans

    Background

    Sympathetic activation of brown adipose tissue (BAT) thermogenesis can ameliorate obesity and related metabolic abnormalities. However,...

    Yuka Ishida, Mami Matsushita, ... Kazuhiro Nakayama in International Journal of Obesity
    Article Open access 17 April 2024

  4. ChREBP-regulated lipogenesis is not required for the thermogenesis of brown adipose tissue

    Objectives

    Brown adipose tissue (BAT) plays a critical role in energy expenditure by uncoupling protein 1 (UCP1)-mediated thermogenesis and represents...

    Chunchun Wei, ** Wang, ... Wei** J. Zhang in International Journal of Obesity
    Article 12 February 2022

  5. Light-emitting diode (LED) photobiomodulation regulates thermogenesis and lipogenesis markers in adipose tissue and improves anthropometric and metabolic parameters in obese mice

    To evaluate the effects of Light-Emitting Diode (LED) irradiation on the expression of thermogenesis and lipogenesis-associated markers in adipose...

    Mauro Célio Ribeiro Silva, Lílian Betânia Reis Amaro, ... André Luiz Sena Guimarães in Lasers in Medical Science
    Article 15 March 2023

  8. Diurnal variations of brown fat thermogenesis and fat oxidation in humans

    Background/objectives

    Disturbed circadian rhythm is associated with an increased risk of obesity and metabolic disorders. Brown adipose tissue (BAT)...

    Mami Matsushita, Shinsuke Nirengi, ... Masayuki Saito in International Journal of Obesity
    Article Open access 02 August 2021

  9. An updated view on human neonatal thermogenesis

    Ismael González-García, Adela Urisarri, ... Miguel López in Nature Reviews Endocrinology
    Article 14 February 2022

  10. Anti-obesity effects of heat-transformed green tea extract through the activation of adipose tissue thermogenesis

    Background

    Adipose tissue thermogenesis is a potential therapeutic target to increase energy expenditure and thereby combat obesity. The aim of the...

    Hyeonyeong Im, Jaewon Lee, ... Yun-Hee Lee in Nutrition & Metabolism
    Article Open access 03 March 2022

  11. Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism

    Background

    Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure,...

    Juan Liu, Yuzhu Tan, ... Cheng Peng in Chinese Medicine
    Article Open access 19 March 2021

  13. Differences in [18F]FDG uptake in BAT of UCP1 −/− and UCP1 +/+ during adrenergic stimulation of non-shivering thermogenesis

    Background

    Brown adipose tissue (BAT) is a fat tissue found in most mammals that helps regulate energy balance and core body temperature through a...

    Christian T. McHugh, John Garside, ... Rosa T. Branca in EJNMMI Research
    Article Open access 07 November 2020

  14. mTOR signaling in Brown and Beige adipocytes: implications for thermogenesis and obesity

    Brown and beige adipocytes are mainly responsible for nonshivering thermogenesis or heat production, despite the fact that they have distinguished...

    Yuqing Ye, Hailan Liu, ... Fang Hu in Nutrition & Metabolism
    Article Open access 06 November 2019

  15. The novel importance of miR-143 in obesity regulation

    Obesity and substantially increased risk of metabolic diseases have become a global epidemic. microRNAs have attracted a great deal of attention as a...

    Jie Liu, Huan Wang, ... Yongliang Zhang in International Journal of Obesity
    Article 17 December 2022

  16. A new way to ignite thermogenesis in human adipose tissue

    Anthony R. P. Verkerke, Shingo Kajimura in Nature Reviews Endocrinology
    Article 08 July 2020

  17. [11C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue

    Purpose

    Photoperiod determines the metabolic activity of brown adipose tissue (BAT) and affects the food intake and body mass of mammals. Sympathetic...

    Lihua Sun, Richard Aarnio, ... Anne Roivainen in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 27 September 2022

  18. The evolving view of thermogenic fat and its implications in cancer and metabolic diseases

    The incidence of metabolism-related diseases like obesity and type 2 diabetes mellitus has reached pandemic levels worldwide and increased gradually....

    **npeng Yin, Yuan Chen, ... Qiang Xu in Signal Transduction and Targeted Therapy
    Article Open access 16 September 2022

  19. mTORC1 in energy expenditure: consequences for obesity

    In eukaryotic cells, the mammalian target of rapamycin complex 1 (sometimes referred to as the mechanistic target of rapamycin complex 1; mTORC1)...

    Camille Allard, Cristina Miralpeix, ... Daniela Cota in Nature Reviews Endocrinology
    Article 15 January 2024

  20. Pulling the trigger: Noncoding RNAs in white adipose tissue browning

    White adipose tissue (WAT) serves as the primary site for energy storage and endocrine regulation in mammals, while brown adipose tissue (BAT) is...

    Dehuan Liang, Guo** Li in Reviews in Endocrine and Metabolic Disorders
    Article 29 December 2023
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