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The relationship between SGLT2 and systemic blood pressure regulation
The sodium-glucose cotransporter 2 (SGLT2) is a glucose transporter that is located within the proximal tubule of the kidney’s nephrons. While it is...
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Reference values for trans-laminar cribrosa pressure difference and its association with systemic biometric factors
ObjectivesTo provide reference values of trans-laminar cribrosa pressure difference (TLCPD) and reveal the association of TLCPD with systemic...
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Venous return and mean systemic filling pressure: physiology and clinical applications
Venous return is the flow of blood from the systemic venous network towards the right heart. At steady state, venous return equals cardiac output, as...
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Effects of positive end-expiratory pressure on brain oxygenation, systemic oxygen cascade and metabolism in acute brain injured patients: a pilot physiological cross-sectional study
Patients with acute brain injury (ABI) often require the application of positive end-expiratory pressure (PEEP) to optimize mechanical ventilation...
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Communicating hydrocephalus and raised intracranial pressure in association with multi-systemic smooth muscle dysfunction syndrome (MSMDS)
Multi-systemic smooth muscle dysfunction syndrome (MSMDS) is extremely rare and can manifest in multiple ways. Associated hydrocephalus has not yet...
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Changes in mean systemic filling pressure as an estimate of hemodynamic response to anesthesia induction using propofol
BackgroundEven a small change in the pressure gradient between the venous system and the right atrium can have significant hemodynamic effects. Mean...
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Analogue Mean Systemic Filling Pressure: a New Volume Management Approach During Percutaneous Left Ventricular Assist Device Therapy
The absence of an accepted gold standard to estimate volume status is an obstacle for optimal management of left ventricular assist devices (LVADs)....
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A Rare Case of Renal Crisis in Systemic Sclerosis–Systemic Lupus Eritematosus Overlap Syndrome: A Case Report and Literature Review
We present a patient with systemic sclerosis–systemic lupus eritematosus (SSc-SLE) overlap syndrome who was initially diagnosed as SLE. The patient...
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Systemic Disease and Portal Hypertension
Purpose of ReviewThe development of portal hypertension is typically a consequence of liver cirrhosis due mainly to primary liver disorders, whereas...
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Systemic immune-inflammatory index and systemic inflammation response index in predicting renal impairment in children with type 1 diabetes mellitus
BackgroundThe aim of this study was to investigate the role of systemic immune-inflammatory index and systemic inflammation response index in...
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Vasopressin as adjunctive therapy in pulmonary hypertension associated with refractory systemic hypotension in term newborns
ObjectiveThe use of vasopressin as an adjunctive therapy in pulmonary hypertension associated with refractory systemic hypotension has increased. The...
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Systemic Lupus Erythematosus in Children
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, that mainly affects skin, joints and kidneys but can affect any organ in the...
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Endoscopic Ultrasound-Guided Porto-systemic Pressure Gradient Measurement Correlates with Histological Hepatic Fibrosis
Background and AimsEndoscopic ultrasound is a novel diagnostic approach to chronic liver diseases (CLDs), and EUS-guided porto-systemic pressure...
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Esmolol response in septic shock patients in relation to vascular waterfall phenomenon measured by critical closure pressure and mean systemic filling pressure: a prospective observational study
BackgroundBedside measurements of critical closure pressure (Pcc) and mean systemic circulation filling pressure (Pmsf) were utilized to evaluate the...
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De novo normotensive scleroderma renal crisis six years after living-donor renal transplantation in a patient with overlap** systemic sclerosis/systemic lupus erythematosus syndrome: a case report
BackgroundScleroderma renal crisis (SRC) is a critical kidney involvement of systemic sclerosis (SSc), often resulting in end-stage renal disease....
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Is measurement of central venous pressure required to estimate systemic vascular resistance? A retrospective cohort study
BackgroundThe clinical range of central venous pressure (CVP) (typically 5 to 15 mmHg) is much less than the range of mean arterial blood pressure...
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Myopericarditis revealing a systemic sclerosis-systemic lupus erythematosus overlap syndrome complicated by fatal cytomegalovirus infection: a case report
BackgroundSystemic sclerosis (SSc)-systemic lupus erythematosus (SLE) overlap syndrome is rarely described in the literature, and its morbidity and...
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Systemic bevacizumab for treatment of recurrent respiratory papillomatosis
ObjectivesTo characterize treatment response of recurrent respiratory papillomatosis (RRP) including adult-onset RRP (AORRP) and juvenile-onset RRP...
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Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients
AimTo study effect of change in position (supine and standing) on pulmonary artery pressure (PAP) in ambulatory heart failure (HF) patients.
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