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Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status
Purpose of reviewTo review the current status of kidney tumor ablation in patients with substantial kidney impairment.
Recent findings ... -
Substantial but spatially heterogeneous progress in male circumcision for HIV prevention in South Africa
BackgroundVoluntary medical male circumcision (VMMC) reduces the risk of male HIV acquisition by 60%. Programmes to provide VMMCs for HIV prevention...
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Knees with anteromedial osteoarthritis show a substantial phenotypic variation prior and following medial unicompartmental knee arthroplasty
PurposeThe primary aim of this study was to evaluate the phenotypic variation using the Coronal Plane Alignment of the Knee (CPAK) classification...
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Substantial influence of psychological factors on return to sports after anterior shoulder instability surgery: a systematic review and meta-analysis
PurposeThis systematic review and meta-analysis aimed to (1) determine the proportion of patients who underwent anterior shoulder instability surgery...
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Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review
BackgroundThe present systematic review investigated the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and...
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Exploring the feasibility of using the ICER Evidence Rating Matrix for Comparative Clinical Effectiveness in assessing treatment benefit and certainty in the clinical evidence on orphan therapies for paediatric indications
BackgroundThe evaluation of clinical evidence takes account of health benefit (efficacy and safety) and the degree of certainty in the estimate of...
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Liver fibrosis indices associated with substantial hematoma expansion in Chinese patients with primary intracerebral hemorrhage
BackgroundWhether liver fibrosis is associated with increased risk for substantial hematoma expansion (HE) after intracerebral hemorrhage (ICH) is...
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Low rate of substantial loss of reduction immediately after hardware removal following acromioclavicular joint stabilization using a suspensory fixation system
PurposeTo evaluate immediate loss of reduction in patients undergoing hardware removal after arthroscopically assisted acromioclavicular (AC) joint...
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Custom TKA combined with personalised coronal alignment yield improvements that exceed KSS substantial clinical benefits
PurposeThe purpose of this study was to report Knee Society Scores (KSS) at 12-month follow-up in a series of 266 knees that received custom TKA. The...
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Minimal clinically important difference (MCID) and substantial clinical benefit (SCB) of upper extremity PROMIS scores following arthroscopic rotator cuff repairs
PurposeTo calculate and determine what factors are associated with achieving the Minimal Clinically Important Difference (MCID) and the Substantial...
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The “Gateway” hypothesis: evaluation of evidence and alternative explanations
BackgroundElectronic nicotine delivery systems (ENDS) offer a substantial harm reduction opportunity for adults who smoke and are unlikely to quit....
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Real-world evidence for coverage determination of treatments for rare diseases
Health technology assessment (HTA) decisions for pharmaceuticals are complex and evolving. New rare disease treatments are often approved more...
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Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy
The immune response against cancer is orchestrated by various parameters and site-dependent specificities have been poorly investigated. In our...
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Substantial health and economic burden of COVID-19 during the year after acute illness among US adults at high risk of severe COVID-19
BackgroundPost-COVID conditions encompass a range of long-term symptoms after SARS-CoV-2 infection. The potential clinical and economic burden in the...
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Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptomatic state (PASS) of upper extremity PROMIS scores in idiopathic adhesive capsulitis
IntroductionThe purpose of this study is to calculate the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and...
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Values derived from patient reported outcomes in spine surgery: a systematic review of the minimal clinically important difference, substantial clinical benefit, and patient acceptable symptom state
PurposeWhile patient reported outcome measures (PROMs) define value in spine surgery, several values such as minimal clinically important difference...
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Common misunderstandings of evidence-based medicine
Currently, most evidence assessments in guidelines or health technology assessments (HTAs) rely on the assumption that a randomized controlled trial...
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Living evidence and adaptive policy: perfect partners?
BackgroundWhile there has been widespread global acceptance of the importance of evidence-informed policy, many opportunities to inform health policy...
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The Evidence for Implantable Sacral Neuromodulation in Pediatric Voiding Dysfunction
Purpose of ReviewThe purpose of this review is to evaluate the evidence regarding the efficacy and safety of implantable sacral neuromodulation (SNM)...