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The clinical trial of alternative relugolix administration for uterine leiomyoma prior to surgically treatment: a study protocol for Non-Adverse Relugolix Administration (NARA) trial
BackgroundUterine leiomyomas are common for reproductive-aged women and affect women’s quality of life due to heavy menstrual bleeding or...
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Changes in vital signs during adrenaline administration for hemostasis in intracordal injection: an observational study with a hypothetical design of endotracheal adrenaline administration in cardiopulmonary arrest
BackgroundThe background is that intravenous adrenaline administration is recommended for advanced cardiovascular life support in adults and...
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Rate and predictors of blood culture positivity after antibiotic administration: a prospective single-center study
PurposeBlood culture obtainment prior to antibiotic administration, in patients with suspected infection, is considered the best practice in...
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Comparison of the effect of combined administration of intravenous and intra-articular tranexamic acid versus their administration alone in the management of blood loss in total knee arthroplasty: a prospective, multicenter study in Iran
BackgroundTotal knee arthroplasty (TKA) is associated with significant blood loss. Antifibrinolytic agents such as tranexamic acid (TXA) are widely...
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Toxicity study of di(2-ethylhexyl)phthalate (DEHP) administration on reproductive parameters in male albino rats
Di(2-ethylhexyl)phthalate (DEHP)-administration was found to be toxic in mammalian systems and also known to affect the male reproduction in rats....
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Risk of Systemic Inflammatory Response Syndrome Following Preoperative Glucocorticoids Administration in Patients After Percutaneous Nephrolithotomy: A Retrospective Cohort Study
IntroductionSystemic inflammatory response syndrome (SIRS) is one of the most serious complications in patients undergoing percutaneous...
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Acute effects of MDMA and LSD co-administration in a double-blind placebo-controlled study in healthy participants
AbstractThere is renewed interest in the use of lysergic acid diethylamide (LSD) in psychiatric research and practice. Although acute subjective...
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Intravenous Medication Administration Safety with Smart Infusion Pumps in the Neonatal Intensive Care Unit: An Observational Study
IntroductionInfants in the neonatal intensive care unit (NICU) are among the most vulnerable patient populations and medication errors are a...
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Risk Factors Associated with Medication Administration Errors in Children: A Prospective Direct Observational Study of Paediatric Inpatients
IntroductionLimited evidence exists regarding medication administration errors (MAEs) on general paediatric wards or associated risk factors exists.
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Immune checkpoint inhibitors and risk of immune-mediated adverse events: a cohort study comparing extended versus standard interval administration
The COVID-19 pandemic precipitated the implementation of extended interval immune checkpoint inhibitors (ICIs) in an effort to limit hospital visits,...
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Efficacy confirmation study of aceneuramic acid administration for GNE myopathy in Japan
BackgroundA rare muscle disease, GNE myopathy is caused by mutations in the GNE gene involved in sialic acid biosynthesis. Our recent phase II/III...
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Pharmacists' knowledge of drug food administration and their appropriate patient counseling a cross-sectional study from Palestine
Pharmacists have a responsibility in the treatment of patients. Interactions between food and drugs may lead to a loss of therapeutic effectiveness...
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Curriculum and assessment tool for less invasive surfactant administration: an international Delphi consensus study
BackgroundTraining and assessment of operator competence for the less invasive surfactant administration (LISA) procedure vary. This study aimed to...
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Efficacy and feasibility of scheduled intravenous acetaminophen administration after pancreatoduodenectomy: a propensity score-matched study
PurposeThe efficiency and safety of routine intravenous administration of acetaminophen after highly invasive hepatobiliary pancreatic surgery remain...
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Contribution of prophylactic administration of flurbiprofen for mesenteric traction syndrome to postoperative leakage or bleeding in gastrointestinal surgery: a retrospective observational study
PurposeMesenteric traction syndrome (MTS) sometimes occurs during abdominal surgery. Prophylactic administration of flurbiprofen, a non-steroidal...
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Effect of tranexamic acid administration on intraoperative blood loss during peritonectomy: a single-center retrospective observational study
BackgroundThe efficacy of tranexamic acid in elective major invasive abdominal surgeries has not yet been established. We investigated the effect of...
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The Impact of Preoperative Dexamethasone Administration on Quality of Recovery Following Laparoscopic Sleeve Gastrectomy: A Prospective Observational Study
IntroductionRecovery from anesthesia is complex and affected by multiple factors. In patient with obesity, the increased prevalence of anxiety and...
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A prospective observational study on impact of epinephrine administration route on acute myocardial infarction patients with cardiac arrest in the catheterization laboratory (iCPR study)
BackgroundEpinephrine is routinely utilized in cardiac arrest; however, it is unclear if the route of administration affects outcomes in acute...
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Coronavirus disease 2019 vaccination acceptance and associated factors among residents of Dire Dawa Administration, Eastern Ethiopia: a community-based cross-sectional study
BackgroundCorona virus disease 2019 (COVID-19) is an extremely contagious viral infection caused by the severe acute respiratory syndrome coronavirus...
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The impact of opioid administration for post gamma knife radiosurgery frame removal: a prospective quality-improvement study
PurposeIn our center, five Gamma Knife proceduralists differed in opioid administration practices prior to Leksell frame removal, providing the...