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  1. The clinical trial of alternative relugolix administration for uterine leiomyoma prior to surgically treatment: a study protocol for Non-Adverse Relugolix Administration (NARA) trial

    Background

    Uterine leiomyomas are common for reproductive-aged women and affect women’s quality of life due to heavy menstrual bleeding or...

    Naoki Kawahara, Ryuji Kawaguchi, ... Fuminori Kimura in Trials
    Article Open access 19 January 2024
  2. Changes in vital signs during adrenaline administration for hemostasis in intracordal injection: an observational study with a hypothetical design of endotracheal adrenaline administration in cardiopulmonary arrest

    Background

    The background is that intravenous adrenaline administration is recommended for advanced cardiovascular life support in adults and...

    Tomohiro Hasegawa, Yusuke Watanabe in Journal of Cardiothoracic Surgery
    Article Open access 06 October 2023
  3. Rate and predictors of blood culture positivity after antibiotic administration: a prospective single-center study

    Purpose

    Blood culture obtainment prior to antibiotic administration, in patients with suspected infection, is considered the best practice in...

    Lior Zornitzki, Lana Anuk, ... Gil Bornstein in Infection
    Article 27 October 2023
  4. Comparison of the effect of combined administration of intravenous and intra-articular tranexamic acid versus their administration alone in the management of blood loss in total knee arthroplasty: a prospective, multicenter study in Iran

    Background

    Total knee arthroplasty (TKA) is associated with significant blood loss. Antifibrinolytic agents such as tranexamic acid (TXA) are widely...

    Mohammadali Fakharian, Arman Fakharian, ... Amir Mohsen Khorrami in BMC Musculoskeletal Disorders
    Article Open access 16 December 2023
  5. Toxicity study of di(2-ethylhexyl)phthalate (DEHP) administration on reproductive parameters in male albino rats

    Di(2-ethylhexyl)phthalate (DEHP)-administration was found to be toxic in mammalian systems and also known to affect the male reproduction in rats....

    Venkataramanaiah Poli, Srinivasulu Reddy Motireddy in Comparative Clinical Pathology
    Article 16 October 2023
  6. Risk of Systemic Inflammatory Response Syndrome Following Preoperative Glucocorticoids Administration in Patients After Percutaneous Nephrolithotomy: A Retrospective Cohort Study

    Introduction

    Systemic inflammatory response syndrome (SIRS) is one of the most serious complications in patients undergoing percutaneous...

    **g** Hu, Chao** Chen, ... Chulian Gong in Drug Safety
    Article 05 March 2024
  7. Acute effects of MDMA and LSD co-administration in a double-blind placebo-controlled study in healthy participants

    Abstract

    There is renewed interest in the use of lysergic acid diethylamide (LSD) in psychiatric research and practice. Although acute subjective...

    Isabelle Straumann, Laura Ley, ... Matthias E. Liechti in Neuropsychopharmacology
    Article Open access 31 May 2023
  8. Intravenous Medication Administration Safety with Smart Infusion Pumps in the Neonatal Intensive Care Unit: An Observational Study

    Introduction

    Infants in the neonatal intensive care unit (NICU) are among the most vulnerable patient populations and medication errors are a...

    Kumiko O. Schnock, Sara E. Rostas, ... Patricia C. Dykes in Drug Safety
    Article 27 October 2023
  9. Risk Factors Associated with Medication Administration Errors in Children: A Prospective Direct Observational Study of Paediatric Inpatients

    Introduction

    Limited evidence exists regarding medication administration errors (MAEs) on general paediatric wards or associated risk factors exists.

    ...
    Johanna I. Westbrook, Ling Li, ... Magdalena Z. Raban in Drug Safety
    Article Open access 05 March 2024
  10. Immune checkpoint inhibitors and risk of immune-mediated adverse events: a cohort study comparing extended versus standard interval administration

    The COVID-19 pandemic precipitated the implementation of extended interval immune checkpoint inhibitors (ICIs) in an effort to limit hospital visits,...

    Amélia Lessard-Roy, Roxanne Marchand, ... Danielle Laurin in Clinical and Experimental Medicine
    Article Open access 22 February 2024
  11. Efficacy confirmation study of aceneuramic acid administration for GNE myopathy in Japan

    Background

    A rare muscle disease, GNE myopathy is caused by mutations in the GNE gene involved in sialic acid biosynthesis. Our recent phase II/III...

    Madoka Mori-Yoshimura, Naoki Suzuki, ... Masashi Aoki in Orphanet Journal of Rare Diseases
    Article Open access 11 August 2023
  12. Pharmacists' knowledge of drug food administration and their appropriate patient counseling a cross-sectional study from Palestine

    Pharmacists have a responsibility in the treatment of patients. Interactions between food and drugs may lead to a loss of therapeutic effectiveness...

    Murad Abualhasan, Shahd Tahan, ... Hiba Zyoud in Journal of Health, Population and Nutrition
    Article Open access 14 September 2023
  13. Curriculum and assessment tool for less invasive surfactant administration: an international Delphi consensus study

    Background

    Training and assessment of operator competence for the less invasive surfactant administration (LISA) procedure vary. This study aimed to...

    Niklas Breindahl, Martin G. Tolsgaard, ... Lise Aunsholt in Pediatric Research
    Article Open access 04 May 2023
  14. Efficacy and feasibility of scheduled intravenous acetaminophen administration after pancreatoduodenectomy: a propensity score-matched study

    Purpose

    The efficiency and safety of routine intravenous administration of acetaminophen after highly invasive hepatobiliary pancreatic surgery remain...

    Katsuhisa Hirano, Takamichi Igarashi, ... Tsutomu Fujii in Surgery Today
    Article 06 February 2023
  15. Contribution of prophylactic administration of flurbiprofen for mesenteric traction syndrome to postoperative leakage or bleeding in gastrointestinal surgery: a retrospective observational study

    Purpose

    Mesenteric traction syndrome (MTS) sometimes occurs during abdominal surgery. Prophylactic administration of flurbiprofen, a non-steroidal...

    Manzo Suzuki, Junpei Shibata, ... Hiroyasu Bito in Langenbeck's Archives of Surgery
    Article 26 August 2023
  16. Effect of tranexamic acid administration on intraoperative blood loss during peritonectomy: a single-center retrospective observational study

    Background

    The efficacy of tranexamic acid in elective major invasive abdominal surgeries has not yet been established. We investigated the effect of...

    Daiki Shirasu, Masahiko Tsuchiya, ... Makoto Satani in JA Clinical Reports
    Article Open access 22 June 2023
  17. The Impact of Preoperative Dexamethasone Administration on Quality of Recovery Following Laparoscopic Sleeve Gastrectomy: A Prospective Observational Study

    Introduction

    Recovery from anesthesia is complex and affected by multiple factors. In patient with obesity, the increased prevalence of anxiety and...

    Mehmet Gokhan Taflan, Yasemin Burcu Ustun, ... Gokhan Selcuk Ozbalci in Obesity Surgery
    Article Open access 12 March 2024
  18. A prospective observational study on impact of epinephrine administration route on acute myocardial infarction patients with cardiac arrest in the catheterization laboratory (iCPR study)

    Background

    Epinephrine is routinely utilized in cardiac arrest; however, it is unclear if the route of administration affects outcomes in acute...

    Ali Aldujeli, Ayman Haq, ... Emmanouil S. Brilakis in Critical Care
    Article Open access 20 December 2022
  19. Coronavirus disease 2019 vaccination acceptance and associated factors among residents of Dire Dawa Administration, Eastern Ethiopia: a community-based cross-sectional study

    Background

    Corona virus disease 2019 (COVID-19) is an extremely contagious viral infection caused by the severe acute respiratory syndrome coronavirus...

    Tafese Dejene Jidha, Endayen Deginet, ... Mickiale Hailu in BMC Infectious Diseases
    Article Open access 11 July 2024
  20. The impact of opioid administration for post gamma knife radiosurgery frame removal: a prospective quality-improvement study

    Purpose

    In our center, five Gamma Knife proceduralists differed in opioid administration practices prior to Leksell frame removal, providing the...

    Jason Hsieh, Wei Wei, ... Lilyana Angelov in Journal of Neuro-Oncology
    Article 25 September 2023
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