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Some new insights into the biological activities of carboxymethylated polysaccharides from Lasiodiplodia theobromae
BackgroundCarboxymethylated Lasiodiplodan (LaEPS-C), Lasiodiplodia theobromae β-glucan exopolysaccharide derivative, has a well-known range of...
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Review on the “Biological Applications of Okra Polysaccharides and Prospective Research”
BackgroundVegetables with edible parts like flowers, fruits, stems, leaves, fibers, roots, and seeds are rich sources of essential vitamins,...
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Synergist for antitumor therapy: Astragalus polysaccharides acting on immune microenvironment
Various new treatments are emerging constantly in anti-tumor therapies, including chemotherapy, immunotherapy, and targeted therapy. However, the...
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Marine macroalgae polysaccharides-based nanomaterials: an overview with respect to nanoscience applications
BackgroundExploration of marine macroalgae poly-saccharide-based nanomaterials is emerging in the nanotechnology field, such as wound dressing, water...
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A review on the applications of Traditional Chinese medicine polysaccharides in drug delivery systems
Traditional Chinese medicine polysaccharides (TCMPs) are plentiful and renewable resources with properties such as biocompatibility, hydrophilicity,...
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Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health
The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity, type 2 diabetes...
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Carboxymethylated Rhizoma alismatis polysaccharides reduces the risk of calcium oxalate stone formation by reducing cellular inflammation and oxidative stress
This study aims to elucidate the mechanism and potential of Rhizoma alismatis polysaccharides (RAPs) in preventing oxidative damage to human renal...
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Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice
BackgroundIn hospitalized patients, drug side effects usually trigger intestinal mucositis (IM), which in turn damages intestinal absorption and...
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Astragalus polysaccharides attenuate rat aortic endothelial senescence via regulation of the SIRT-1/p53 signaling pathway
BackgroundAstragalus polysaccharides (APS) have been verified to have antioxidative and antiaging activities in the mouse liver and brain. However,...
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Extracts of Sida cordifolia contain polysaccharides possessing immunomodulatory activity and rosmarinic acid compounds with antibacterial activity
BackgroundThe overuse of antibiotics has led to increased antimicrobial resistance, but plant-derived biological response modifiers represent a...
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Glycobiology in osteoclast differentiation and function
Glycans, either alone or in complex with glycan-binding proteins, are essential structures that can regulate cell biology by mediating protein...
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Microorganism-derived biological macromolecules for tissue engineering
According to literature, certain microorganism productions mediate biological effects. However, their beneficial characteristics remain unclear....
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Integrated network pharmacology and cellular assay reveal the biological mechanisms of Limonium sinense (Girard) Kuntze against Breast cancer
BackgroundLimonium Sinense (Girard) Kuntze ( L. sinense ) has been widely used for the treatment of anaemia, bleeding, cancer, and other disorders in...
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Nutritional Quality and Biological Application of Mushroom Protein as a Novel Protein Alternative
Purpose of ReviewGlobal concerns about population growth, economic, and nutritional transitions and health have led to the search for a low-cost...
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Pharmacological properties of Polygonatum and its active ingredients for the prevention and treatment of cardiovascular diseases
Despite continued advances in prevention and treatment strategies, cardiovascular diseases (CVDs) remain the leading cause of death worldwide, and...
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The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics
More than 60 years ago, disulfiram (DSF) was employed for the management of alcohol addiction. This promising cancer therapeutic agent inhibits...
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Bioactive potential of natural biomaterials: identification, retention and assessment of biological properties
Biomaterials have had an increasingly important role in recent decades, in biomedical device design and the development of tissue engineering...
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Functional Food Chemical Ingredient Strategies for Non-alcoholic Fatty Liver Disease (NAFLD) and Hepatic Fibrosis: Chemical Properties, Health Benefits, Action, and Application
Purpose of ReviewThe liver is an important digestive gland in the body. Lifestyle and dietary habits are increasingly damaging our liver, leading to...
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Optimization of the Process for Preparing Bivalent Polysaccharide Conjugates to Develop Multivalent Conjugate Vaccines against Streptococcus pneumoniae or Neisseria meningitidis and Comparison with the Corresponding Licensed Vaccines in Animal Models
ObjectiveThis study aimed to describe, optimize and evaluate a method for preparing multivalent conjugate vaccines by simultaneous conjugation of two...
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The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However,...