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Metastasis from follicular lymphoma to an ovarian mature teratoma: a case report of tumor-to-tumor metastasis
BackgroundTumor-to-tumor metastasis (TTM) is a rare but well-established phenomenon where histologically distinct tumors metastasize within each...
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Tumor-to-tumor spread: a case report and literature review of renal cell carcinoma metastasis into thyroid cancer
Tumor-to-tumor metastasis is a rare, yet important entity. Patients with a history of renal cell carcinoma (RCC) may have tumor deposits to the...
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Tumor-derived cell-free DNA and circulating tumor cells: partners or rivals in metastasis formation?
The origin of metastases is a topic that has sparked controversy. Despite recent advancements, metastatic disease continues to pose challenges. The...
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New insights into the correlations between circulating tumor cells and target organ metastasis
Organ-specific metastasis is the primary cause of cancer patient death. The distant metastasis of tumor cells to specific organs depends on both the...
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Solid Pseudopapillary Tumor of the Pancreas: Is Enucleation Safe?
BackgroundWhile solid pseudopapillary tumor (SPT) of the pancreas are oncologically low-risk tumors, their resection with pancreaticoduodenectomy...
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Infiltrative solid papillary carcinoma of the breast with axillary lymph node metastasis: a case report
BackgroundSolid papillary carcinoma (SPC) is a rare breast papillary tumor variant. The main histological features of SPC consist of neoplastic...
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MicroRNAs mediated interaction of tumor microenvironment cells with breast cancer cells during bone metastasis
Breast cancer (BC) bone metastasis is primarily osteolytic and has limited therapeutic options. Metastasized BC cells prime the secondary environment...
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Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis
Circulating tumor cells (CTCs) are precursors of distant metastasis in a subset of cancer patients. A better understanding of CTCs heterogeneity and...
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TREM1+ tumor-associated macrophages secrete CCL7 to promote hepatocellular carcinoma metastasis
PurposeTumor-associated macrophages (TAMs) play a critical role in hepatocellular carcinoma (HCC) progression and metastasis. Systematic...
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Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation
BRAF is frequently mutated in various cancer types and contributes to tumorigenesis and metastasis. As an important switch in RAS signaling pathway,...
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Distinct impacts of radiological appearance on lymph node metastasis and prognosis based on solid size in clinical T1 non-small cell lung cancer
BackgroundSolid nodules (SN) had more aggressive features and a poorer prognosis than part-solid nodules (PSN). This study aimed to evaluate the...
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Chronic pulmonary bacterial infection facilitates breast cancer lung metastasis by recruiting tumor-promoting MHCIIhi neutrophils
Breast cancer can metastasize to various organs, including the lungs. The immune microenvironment of the organs to be metastasized plays a crucial...
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Circulating tumor cells clusters and their role in Breast cancer metastasis; a review of literature
Breast cancer is a significant and deadly threat to women globally. Moreover, Breast cancer metastasis is a complicated process involving multiple...
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Tumor-to-tumor metastasis of colon cancer metastasizing to a pancreatic neuroendocrine tumor associated with von Hippel-Lindau disease: a case report
Von Hippel-Lindau disease (VHL) is frequently associated with pancreatic neuroendocrine tumors (PNETs). Here, we report a case of tumor-to-tumor...
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The role of innate immune cells as modulators of the tumor microenvironment in the metastasis and treatment of pancreatic cancer
Pancreatic cancer is a highly aggressive disease, which is often diagnosed late. Consequently, metastasis is common among newly diagnosed patients,...
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CT target scanning in the diagnosis of solid pseudopapillary tumor of the pancreas
ObjectiveTo discuss the value of computed tomography (CT) iterative reconstruction technique combined with target scanning in the diagnosis of solid...
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The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma
Metastasis remains the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC), in which sustained activation of the Notch...
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Micro-lymph node metastasis in intrahepatic cholangiocarcinoma showing pathological complete response to primary tumor and intrahepatic metastasis treated by gemcitabine plus cisplatin chemotherapy and radical surgery
Surgical resection is the only curative treatment option for achieving long-term survival in biliary tract cancer patients. However, regional lymph...
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Is tumor diameter a risk factor for occult N1 metastasis in patients with peripheral non-small cell lung cancer which is smaller than 3 cm?
The optimum treatment option is surgery for clinical early stage non-small cell lung cancer. Despite all non-invasive and invasive staging effort,...
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Misdiagnosed cystic pancreatic neuroendocrine tumor with bilobar hepatic metastasis managed with single-stage resection — a case report
BackgroundPancreatic neuroendocrine tumors (PNET) account for less than 2% of all pancreatic tumors, while cystic PNETs account for only 10–18% of...
