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Glucose Metabolic Alteration of Cerebral Cortical Subareas in Rats with Renal Ischemia/Reperfusion Based on Small-Animal Positron Emission Tomography
ObjectiveTo investigate glucose metabolic alterations in cerebral cortical subareas using 18 F-labeled glucose derivative fluorodeoxyglucose (FDG)...
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Measuring Pathology in Patients with Multiple Sclerosis Using Positron Emission Tomography
Purpose of ReviewMultiple sclerosis is characterized by a diverse and complex pathology. Clinical relapses, the hallmark of the disease, are...
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Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) of prostate cancer: current and emerging applications
Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) is transforming the management of patients with prostate cancer. In...
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Magnetic Resonance Imaging-Negative Cerebral Amyloid Angiopathy: Cerebrospinal Fluid Amyloid-β42 over Amyloid Positron Emission Tomography
BackgroundCerebral amyloid angiopathy (CAA) pathology is becoming increasingly important in Alzheimer’s disease (AD) because of its potential link to...
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Diagnostic performance of noninvasive imaging using computed tomography, magnetic resonance imaging, and positron emission tomography for the detection of ovarian cancer: a meta-analysis
ObjectiveThe aim of this meta-analysis was to compare the diagnostic value of noninvasive imaging methods computed tomography (CT), magnetic...
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Aluminum Fluoride-18 Labeled Mannosylated Dextran: Radiosynthesis and Initial Preclinical Positron Emission Tomography Studies
PurposeIn addition to being expressed on liver sinusoidal endothelial cells, mannose receptors are also found on antigen-presenting cells, including...
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Glypican-3 targeted positron emission tomography detects sub-centimeter tumors in a xenograft model of hepatocellular carcinoma
BackgroundEarly intrahepatic recurrence is common after surgical resection of hepatocellular carcinoma (HCC) and leads to increased morbidity and...
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Real-time motion-enabling positron emission tomography of the brain of upright ambulatory humans
BackgroundMobile upright PET devices have the potential to enable previously impossible neuroimaging studies. Currently available options are imagers...
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Advances in positron emission tomography tracers related to vascular calcification
Microcalcification, a type of vascular calcification, increases the instability of plaque and easily leads to acute clinical events. Positron...
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Evaluation of [11C]UCB-A positron emission tomography in human brains
BackgroundIn preclinical studies, the positron emission tomography (PET) imaging with [ 11 C]UCB-A provided promising results for imaging synaptic...
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Platelet-derived growth factor receptor β-targeted positron emission tomography imaging for the noninvasive monitoring of liver fibrosis
PurposeNoninvasive quantifying activated hepatic stellate cells (aHSCs) by molecular imaging is helpful for assessing disease progression and...
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Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography
Pharmacokinetic positron emission tomography (PET) studies rely on the measurement of the arterial input function (AIF), which represents the...
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The emerging role of positron emission tomography (PET) in the management of photon radiotherapy-induced vasculitis in head and neck cancer patients
PurposeWhile radiotherapy (RT) for head and neck cancer (HNC) has made recent strides, RT-induced vasculitis continues to adversely affect long-term...
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Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [68Ga]Ga-DOTA-Siglec-9 Positron Emission Tomography in Murine Models of Inflammatory Bowel Disease
PurposeInflammatory bowel disease (IBD) can be imaged with positron emission tomography (PET), but existing PET radiopharmaceuticals have limited...
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Synthesis and preclinical evaluation of novel 18F-vancomycin-based tracers for the detection of bacterial infections using positron emission tomography
IntroductionBacterial infections are a major problem in medicine, and the rapid and accurate detection of such infections is essential for optimal...
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Application of positron emission tomography in psychiatry—methodological developments and future directions
Mental disorders represent an increasing source of disability and high costs for societies globally. Molecular imaging techniques such as positron...
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Identification of a CEACAM5 targeted nanobody for positron emission tomography imaging and near-infrared fluorescence imaging of colorectal cancer
PurposeHere, we aim to identify a CEACAM5-targeted nanobody and demonstrate its application in positron emission tomography (PET) imaging and...
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Assessment of Regional Lung Ventilation with Positron Emission Tomography Using the Radiofluorinated Gas [18F]SF6: Application to an Animal Model of Impaired Ventilation
PurposeClinical ventilation studies are primarily performed with computerized tomography (CT) and more often with single-photon emission Computerized...
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Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET)
PurposeExploring synaptic density changes during brain growth is crucial to understanding brain development. Previous studies in nonhuman primates...
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Imaging immunity in patients with cancer using positron emission tomography
Immune checkpoint inhibitors and related molecules can achieve tumour regression, and even prolonged survival, for a subset of cancer patients with...
