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Long-term and sequential treatment for osteoporosis
Osteoporosis is a skeletal disorder that causes impairment of bone structure and strength, leading to a progressively increased risk of fragility...
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A novel sequential treatment approach between denosumab and romosozumab in patients with severe osteoporosis
SummaryIn severe osteoporosis, the optimal approach for sequential treatment between denosumab and romosozumab is unclear. We utilised a novel...
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A systematic review of cost‑effectiveness analyses of sequential treatment for osteoporosis
Sequential treatment of osteoporosis has been increasingly mentioned in recent years. However, the corresponding systematic review has not been...
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Treatment patterns and outcomes associated with sequential and non-sequential use of CDK4 & 6 inhibitors in patients with HR+, HER2− MBC in the real world
PurposeCyclin Dependent Kinase 4 & 6 inhibitors (CDK4 & 6i) have transformed the management of HR+, HER2− metastatic breast cancer (MBC); however,...
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Comparison of the cost-effectiveness of sequential treatment with abaloparatide in US men and women at very high risk of fractures
BackgroundOsteoporotic-related fractures represent an increasing burden to patients, health care systems and society.
AimsThis study estimated...
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A Promising Approach to Optimizing Sequential Treatment Decisions for Depression: Markov Decision Process
The most appropriate next step in depression treatment after the initial treatment fails is unclear. This study explores the suitability of the...
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Sequential Tocilizumab and Tofacitinib Treatment for Systemic Juvenile Idiopathic Arthritis: a Case Report
Systemic juvenile idiopathic arthritis (sJIA) is a complex and difficult to cure condition with high disability and mortality rates. Herein, we...
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The Sequential Therapy in Osteoporosis
BackgroundOsteoporosis management often involves a sequential treatment approach to optimize patient outcomes and minimize fracture risks. This...
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The safety and efficacy of sequential intramuscular/oral ziprasidone treatment of acute episode in patients with schizophrenia: a multicenter, open-labeled study
BackgroundZiprasidone mesylate injection is an atypical antipsychotic drug which is recently approved in China. In combination with its oral...
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Early echocardiographic evaluation of right ventricular load adaptability after sequential combination treatment in pulmonary arterial hypertension
BackgroundUsing the tricuspid annular plane systolic excursion (TAPSE)/pulmonary arterial systolic pressure (PASP) ratio as an index of right...
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Comparative efficacy of sequential treatment and open abdomen approaches for corrosive abdominal hemorrhage due to inadequate drainage of duodenal leakage: a cohort study
BackgroundIntra-abdominal bleeding resulting from inadequate drainage of duodenal leakage (DL) is typically caused by the corrosiveness of duodenal...
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Concurrent/sequential versus sequential immune checkpoint inhibition in inoperable large stage III non-small cell lung cancer patients treated with chemoradiotherapy: a prospective observational study
Purpose/aimThe international standard for patients with large inoperable stage III NSCLC is durvalumab consolidation after concurrent...
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Simultaneous Integrated Boost (SIB) Versus Sequential Boost in Anal Cancer Patients: A Single-Center Experience
PurposeConcurrent chemoradiation is the standard of care for the treatment of anal cancer. Radiation can be delivered by sequential or simultaneous...
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Sequential treatment of teriparatide and alendronate versus alendronate alone for elevation of bone mineral density and prevention of refracture after percutaneous vertebroplasty in osteoporosis: a prospective study
BackgroundPercutaneous vertebroplasty was the most common strategy for osteoporotic vertebral compression fracture. However, refracture after...
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Novel concept of “sequential particle radiotherapy” with atezolizumab plus bevacizumab for hepatocellular carcinoma with portal vein tumor thrombus
Owing to the high objective response rate of atezolizumab plus bevacizumab (Atez/Bev) for hepatocellular carcinoma (HCC), the concept of sequential...
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Defining Normal Sequential Swallowing Biomechanics
Little is known about the physiology of a common fluid ingestion pattern—sequential swallowing. This study investigated sequential swallowing...
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Oral sequential therapy in the treatment of post-surgical epidural abscess and subdural empyema
PurposeThe management of post-surgical subdural empyema and subdural abscess is not standardised. The objective was to analyse the efficacy and...
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Sequential correction using satellite rod for the treatment of severe rigid spinal deformity: a retrospective study of 19 cases
ObjectivesThe purpose of this study was to evaluate the effectiveness of sequential correction using satellite rod in patients with severe rigid...
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Evaluation of two modalities of perioperative treatment in the management of extremity and truncal soft tissue sarcomas: neoadjuvant concurrent chemoradiotherapy and sequential treatment
PurposePatients with locally advanced grade 2–3 extremity/truncal soft tissue sarcomas (STS) are at high risk of recurrence. The objective of this...
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TACE plus tyrosine kinase inhibitors and immune checkpoint inhibitors versus TACE plus tyrosine kinase inhibitors for the treatment of patients with hepatocellular carcinoma: a meta-analysis and trial sequential analysis
BackgroundWe conducted a meta-analysis and trial sequential analysis (TSA) to compare the therapeutic efficacy and adverse events (AEs) between the...
