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The immunohistochemical expression of SSTR2A is an independent prognostic factor in meningioma
The expression of somatostatin receptors in meningioma is well established. First, suggestions of a prognostic impact of SSTRs in meningioma have...
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An algorithmic approach utilizing CK7, TTF1, beta-catenin, CDX2, and SSTR2A can help differentiate between gastrointestinal and pulmonary neuroendocrine carcinomas
Primary gastrointestinal neuroendocrine carcinoma (GI-NEC) cannot be distinguished morphologically from pulmonary neuroendocrine carcinoma (P-NEC)....
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Somatostatin receptor subtype 2A expression and genetics in 184 paragangliomas: a single center retrospective observational study
PurposeAdrenal and extra-adrenal paragangliomas (PGLs) are a group of neuroendocrine tumors (NETs) with strong heterogeneity, which often express...
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Expression of potential therapeutic target SSTR2a in primary and metastatic non-keratinizing nasopharyngeal carcinoma
Somatostatin receptor 2a (SSTR2a) is an important diagnostic and scintigraphic marker in several tumors, as well as a potential therapeutic target....
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Surgical resection of double advanced pancreatic neuroendocrine tumors with multiple renal cell carcinoma associated with von Hippel–Lindau disease
Von Hippel–Lindau (VHL) disease, an autosomal dominant genetic disorder caused by a germline mutation, is associated with non-functional and...
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Immunohistochemical Expression Pattern of Theragnostic Targets SSTR2 and PSMA in Endolymphatic Sac Tumors: A Single Institution Case Series
BackgroundEndolymphatic sac tumors are rare neoplasia characterized by slow growth. However, their clinical impact should not be underestimated,...
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Apoptosis-related factors are relevant to progression of pancreatic neuroendocrine tumors
BackgroundMultidisciplinary therapy centered on antitumor drugs is indicated in patients with unresectable pancreatic neuroendocrine tumors (PanNET)....
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Differences in somatostatin receptor subtype expression in patients with acromegaly: new directions for targeted therapy?
PurposeTo analyze the expression of somatostatin receptor (SSTR)2a and 5 by immunohistochemistry (IHC) in surgically resected somatotrophic pituitary...
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Gastric Amphicrine Carcinoma Showing Neuroendocrine and Pancreatic Acinar Cell Differentiation. Lesson from a Challenging Case Opening New Perspectives in the Diagnostic Work-Up of Gastric Neuroendocrine Neoplasms
Amphicrine carcinomas are epithelial neoplasms composed of cells with co-existing exocrine-neuroendocrine phenotype and are challenging lesions from...
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FNA of Meningioma with Rhabdoid Features Presenting as a Lateral Neck Mass
Primary meningioma at extracranial head and neck sites is uncommon. Since fine needle aspiration (FNA) is often the first line diagnostic modality...
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Calcifying pseudoneoplasm of neuroaxis (CAPNON): a comprehensive immunohistochemical and morphological characterization of five cases
Calcifying pseudoneoplasm of neuroaxis (CAPNON) is a rare lesion of the central nervous system with uncertain histogenesis. We further explored...
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Histopathologic features of nasal glial heterotopia (nasal glioma)
PurposeNasal glioneuronal heterotopia (NGH) is an uncommon developmental abnormality of the nasal cavity or paranasal soft tissue. Few detailed...
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SSTR2A expression in medullary thyroid carcinoma is correlated with longer survival
PurposeMedullary thyroid carcinoma (MTC) derives from the parafollicular C-cells of the thyroid gland. Somatostatin receptors (SSTRs) are expressed...
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Peptide radionuclide radiation therapy with Lutathera in multirecurrent nonanaplastic meningiomas: antitumoral activity study by growth rate analysis
PurposeSeveral retrospective studies and meta-analyses of Peptide Radionuclide Radiation Therapy in meningiomas suggest six-month progression-free...
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Gastroenteropankreatische neuroendokrine Neoplasien
Neuroendocrine neoplasms of the gastroenteropancreatic system are subdivided based on morphological criteria into well-differentiated neuroendocrine...
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Somatostatin receptor subtype expression and radiomics from DWI-MRI represent SUV of [68Ga]Ga-DOTATOC PET in patients with meningioma
ObjectiveThis retrospective study aimed to analyse the correlation between somatostatin receptor subtypes (SSTR 1–5) and maximum standardized uptake...
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Neuroendokrine Neoplasien
The gastrointestinal tract represents, together with the lung, the most common site for the occurrence of neuroendocrine neoplasms (NEN). NEN include...
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Praktische Anwendung von Immunhistochemie in pankreatischen neuroendokrinen Neoplasien
Pancreatic neuroendocrine neoplasms (PanNEN) are rather rare entities. Morphology, combined with immunohistochemistry, allows ty** and grading,...
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Malignant perineurioma derived from the retroperitoneum with an aggressive clinical course: a case report
BackgroundMalignant perineurioma is a rare malignant counterpart of perineurioma derived from perineural cells. Resection is the primary option for...