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Analysis of retinal and choroidal microvascular changes using optical coherence tomography and optical coherence tomography angiography in patients with acute leukemia
PurposeAlthough leukemic retinopathy accounts for 80% of ocular complications in acute leukemia, its pathogenesis remains unclear. To evaluate...
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Effect of obstructive sleep apnoea on retinal microvascular function: a randomised controlled trial
PurposeRetinal microvascular endothelial dysfunction is thought to be of importance in the development of ocular vascular diseases. Obstructive sleep...
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Retinal microvascular associations with cardiometabolic risk factors differ by diabetes status: results from the UK Biobank
Aims/hypothesisThe aim of the study was to examine the association of retinal vessel morphometry with BP, body composition and biochemistry, and to...
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The association of microvascular disease and endothelial dysfunction with vertebral trabecular bone mineral density
SummaryRetinopathy and albuminuria are associated with hip fracture risk. We investigated whether these disorders and endothelial dysfunction (which...
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Retinal ultrastructural, electrophysiological, and microvascular morphological outcomes in diabetic macular edema treated with intravitreal bevacizumab
BackgroundInvestigation of retinal ultrastructural, electrophysiological, and microvascular morphological changes, as well as correlations between...
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Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes
BackgroundDiabetes mellitus is a chronic disease which is detrimental to cardiovascular health, often leading to secondary microvascular...
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Subclinical microvascular changes in ANCA-vasculitides: the role of optical coherence tomography angiography and nailfold capillaroscopy in the detection of disease-related damage
BackgroundBoth cardiovascular and complement-mediated disorders might lead to microvascular damages in anti-neutrophil cytoplasm autoantibodies...
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Unveiling the retinal secrets of neuromyelitis optica spectrum disorder
BackgroundVascular alterations are now recognized as important contributors to the pathophysiology of neuromyelitis optica spectrum disorder (NMOSD)....
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The neurovascular retinal involvement in a large population of patients recovered from COVID-19: an OCT and OCT angiography study
BackgroundThis study aimed to assess the neuronal and microvascular retinal and choroidal involvement in COVID-19 recovered patients using optical...
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Retinochoroidal microvascular changes in newly developed obese children: an optical coherence tomography angiography study
BackgroundChildhood obesity was associated with retinochoroidal microvascular changes using optical coherence tomography angiography (OCTA), but...
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Prognostic potentials of AI in ophthalmology: systemic disease forecasting via retinal imaging
BackgroundArtificial intelligence (AI) that utilizes deep learning (DL) has potential for systemic disease prediction using retinal imaging. The...
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Incretins and microvascular complications of diabetes: neuropathy, nephropathy, retinopathy and microangiopathy
Glucagon-like peptide-1 receptor agonists (GLP-1RAs, incretin mimetics) and dipeptidyl peptidase-4 inhibitors (DPP-4is, incretin enhancers) are...
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Peripheral and ocular microvascular alterations in systemic sclerosis: observations from capillaroscopic assessments, perfusion peripheral analysis, and optical coherence tomography angiography
To investigate the correlations between finger microvascular morphology and function in patients with systemic sclerosis (SSc) and the status of...
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Ocular biomarkers of cognitive decline based on deep-learning retinal vessel segmentation
BackgroundThe current literature shows a strong relationship between retinal neuronal and vascular alterations in dementia. The purpose of the study...
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Investigation of associations between retinal microvascular parameters and albuminuria in UK Biobank: a cross-sectional case-control study
BackgroundAssociations between microvascular variation and chronic kidney disease (CKD) have been reported previously. Non-invasive retinal fundus...
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Insight into the Brain: Application of the Retinal Microvasculature as a Biomarker for Cerebrovascular Diseases through Optical Coherence Tomography Angiography
Purpose of ReviewThe present article serves as a comprehensive review of the published research literature surrounding the retinal microvasculature,...
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Retinal OCT biomarkers and their association with cognitive function—clinical and AI approaches
Retinal optical coherence tomography (OCT) biomarkers have the potential to serve as early, noninvasive, and cost-effective markers for identifying...
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Diastolic left ventricular function in relation to the retinal microvascular fractal dimension in a Flemish population
Fractal analysis provides a global assessment of vascular networks (e.g., geometric complexity). We examined the association of diastolic left...
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Retinal microvascular parameters are not associated with diabetes in the Northern Ireland Cohort for the Longitudinal Study of Ageing
BackgroundThe retinal microvasculature offers unique non-invasive evaluation of systemic microvascular abnormalities. Previous studies reported...
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Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders
BackgroundSchizophrenia spectrum disorders (SSDs) are presumed to be associated with retinal thinning. However, evidence is lacking as to whether...
