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The association between paramedic service system hospital offload time and response time
ObjectiveTo address an important care issue in Canada, we tested the association between paramedic system hospital offload and response time, while...
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Relationships among Grip Strength Measurement, Response Time, and Frailty Criteria
BackgroundMuscle response in older adults is believed to decrease with maximal muscle strength, although it has not been adequately assessed;...
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Patient adherence and response time in electronic patient-reported outcomes: insights from three longitudinal clinical trials
PurposePatient-reported outcome measures (PROMs) are used to collect data on disease symptoms in support of clinical trial endpoints. Clinical...
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Response time and response time variability as indicators of response quality during static automated perimetry
PurposePerimetry is a both demanding and strenuous examination method that is often accompanied by signs of fatigue, leading to false responses and...
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Patient eligibility for trials with imaging response assessment at the time of molecular tumor board presentation
PurposeTo assess the eligibility of patients with advanced or recurrent solid malignancies presented to a molecular tumor board (MTB) at a large...
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Capillary refill time response to a fluid challenge or a vasopressor test: an observational, proof-of-concept study
BackgroundSeveral studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT...
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Assessing the treatment response of lateral elbow tendinopathy using time-dependent ultrasonography, Doppler imaging, and elastography
ObjectiveTo investigate the structural alterations, neovascularity, and elasticity of tendons and the relationship between elasticity and the Patient...
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Characteristics of tummy time and dose-response relationships with development in infants
This study aimed to examine change in tummy time patterns and preferences in the first 6 months of life, as well as dose–response relationships...
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A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure–response relationships: a proof-of-concept study with alectinib
PurposeIn exposure–response analyses of oral targeted anticancer agents, longitudinal plasma trough concentrations are often aggregated into a single...
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Management of Dysregulated Immune Response in the Critically Ill
This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new...
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Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis
BackgroundAlthough vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the...
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Visual acuity time in range: a novel concept to describe consistency in treatment response in diabetic macular oedema
ObjectiveTo assess ‘time in range’ as a novel measure of treatment response in diabetic macular oedema (DMO).
MethodsThis post hoc analysis of the...
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RETRACTED ARTICLE: Childhood obesity risk increases with increased screen time: a systematic review and dose–response meta-analysis
BackgroundThe role of screen time in promoting obesity among children has been reported in previous studies. However, the effects of different screen...
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T2 relaxation time for the early prediction of treatment response to chemoradiation in locally advanced rectal cancer
ObjectivesPoor responders to chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC) can still have a good prognosis if the treatment...
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Personalized glycemic response led digital therapeutics program improves time in range in a period of 14 days
BackgroundLifestyle modification is an integral aspect for the management of type 2 diabetes (T2D). However, it is difficult to ensure the accuracy...
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Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies
Background and objectivePhysical activity has benefits for the cardiovascular system, however, what levels and types of activity provide optimal...
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Sex bias in immune response: it is time to include the sex variable in studies of autoimmune rheumatic diseases
Healthy females and males differ in their immune cell composition and function and females generally mount stronger immune response than males and...
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Prolonged mean response time in older adults with cardiovascular risk compared to healthy older adults
BackgroundDuring incremental exercise (Inc-Ex), the mean response time (MRT) of oxygen uptake (V̇O 2 ) represents the time delay before changes in...
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Multistate modelling of probability of on-treatment clinical response and time remaining in response in patients with moderate-to-severe psoriasis treated with brodalumab or ustekinumab in the AMAGINE-2 and -3 studies
BackgroundRelative changes in Psoriasis Area and Severity Index (PASI) are used as outcomes in psoriasis clinical trials but are limited when...
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The impact of antibiotics on clinical response over time in uncomplicated cellulitis: a systematic review and meta-analysis
PurposeAntibiotic treatment of uncomplicated cellulitis is highly variable with respect to agent, dose, and route of administration. As there is...
