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Lower respiratory tract infections among newly diagnosed sleep apnea patients
BackgroundSleep apnea is associated with chronic comorbidities and acute complications. Existing data suggest that sleep apnea may predispose to an...
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Impact of COVID-19 pandemic: increase in complicated upper respiratory tract infections requiring ENT surgery?
PurposeThis study investigates the impact of the COVID-19 pandemic on complicated upper respiratory tract infections requiring surgical intervention...
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Burden of human metapneumovirus infections among children with acute respiratory tract infections attending a Tertiary Care Hospital, Kathmandu
BackgroundAcute respiratory infections (ARIs) are one of the most common causes of mortality and morbidity worldwide. Every year millions of children...
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Role of multi-strain probiotics in preventing severity and frequency of recurrent respiratory tract infections in children
BackgroundRespiratory tract infections are among the most common infections in the pediatric population throughout the globe. Globally around 20% of...
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Determinants of antibiotic prescription in children with adenovirus respiratory tract infections
We performed this study to evaluate factors associated with antibiotic prescriptions in children with adenovirus infection, since no studies have...
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Assessment and clinical utility of metagenomic next-generation sequencing for suspected lower respiratory tract infections
ObjectivesThis study aims to compare the diagnostic efficacy of metagenomic next-generation sequencing (mNGS) to traditional diagnostic methods in...
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OM-85 BV in pediatric recurrent respiratory tract infections: a cost-utility analysis
BackgroundDespite the growing evidence on efficacy, little is known regarding the cost-utility of Vaxom/Imocur (OM-85 BV) supplementation to decrease...
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Old foes following news ways?—Pandemic-related changes in the epidemiology of viral respiratory tract infections
IntroductionFollowing lockdown periods and restricting public health measures in response to the COVID-19 pandemic, respiratory tract infections...
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Recurrent upper respiratory tract infections in early childhood: a newly defined clinical condition
BackgroundRecurrent Upper Respiratory Tract Infections (R-URTIs) pose a significant challenge in pediatric healthcare, affecting both children and...
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Procalcitonin Guided Antibiotic Stewardship in Pediatric Sepsis and Lower Respiratory Tract Infections
ObjectivesTo determine the impact of procalcitonin-guided antibiotic stewardship protocol (PCT-ASP) in children admitted with sepsis and lower...
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Clinical recommendations for the inpatient management of lower respiratory tract infections in children and adolescents with severe neurological impairment in Germany
Children and adolescents with severe neurological impairment (SNI) require specialized care due to their complex medical needs. In particular, these...
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Association of low physical activity with higher respiratory tract infections frequency among pre-school children
BackgroundThere is no consensus on the benefits of physical activity (PA) regarding upper respiratory tract infections (URTIs) among children. This...
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Parental engagement in research on paediatric lower respiratory tract infections in Indonesia
BackgroundLower respiratory tract infections (LRTIs) in children are a major concern in Indonesia as it is the leading cause of morbidity and...
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Podotimod in pediatric recurrent respiratory tract infections: a cost-utility analysis
IntroductionDespite the growing evidence on efficacy, few economic evaluations have evaluated the cost-utility of Pidotimod (PDT) supplementation to...
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Best Practices for Identifying Hospitalized Lower Respiratory Tract Infections Using Administrative Data: A Systematic Literature Review of Validation Studies
IntroductionEstimating the burden of lower respiratory tract infections (LRTIs) increasingly relies on administrative databases using International...
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Myasthenia gravis, respiratory function, and respiratory tract disease
Myasthenia gravis (MG) is characterized by muscle weakness caused by autoantibodies that bind to the postsynaptic membrane at the neuromuscular...
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Respiratory virus infections of the lower respiratory tract elevate bronchoalveolar lavage eosinophil fraction: a clinical retrospective study and case review
BackgroundEosinophilic airway inflammation caused by respiratory virus infection has been demonstrated in basic research; however, clinical...
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Clinical significance of human metapneumovirus detection in critically ill adults with lower respiratory tract infections
BackgroundUnlike other viruses, the pathogenicity of human metapneumovirus (hMPV) in adults remains uncertain. To address this question, a...
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Study protocol: infectious diseases consortium (I3D) for study on integrated and innovative approaches for management of respiratory infections: respiratory infections research and outcome study (RESPIRO)
BackgroundCommunity-acquired respiratory infections are a leading cause of illness and death globally. The aetiologies of community-acquired...
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Metabolomics in pediatric lower respiratory tract infections and sepsis: a literature review
AbstractLower respiratory tract infections (LRTIs) are a leading cause of morbidity and mortality in children. The ability of healthcare providers to...