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Relationship between cerebrospinal fluid/serum albumin quotient and phenotype in amyotrophic lateral sclerosis: a retrospective study on 328 patients
BackgroundWe analysed the relationship between cerebrospinal fluid (CSF)/serum albumin quotient (Q-Alb) and phenotype in a large cohort of patients...
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Pharmacokinetics of Buprenorphine Buccal Film and Orally-administered Oxycodone in a Respiratory Study: An Analysis of Secondary Outcomes from a Randomized Controlled Trial
ObjectiveTo evaluate pharmacokinetic (PK) parameters and oxygen saturation as markers of abuse potential after administration of buprenorphine buccal...
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Neonatal respiratory support related to lung function abnormalities in school-age children with bronchopulmonary dysplasia
ObjectiveTo elucidate the relationship between abnormal lung function (LF) at school age and neonatal respiratory support in very low birth weight...
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Variance in respiratory quotient among daily activities and its association with obesity status
Background/objectivesThe ability to adapt the level of daily fuel utilization to substrate availability is given by the respiratory quotient (RQ),...
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High-sensitivity Troponin I and Ablation Effectiveness Quotient after Ablation Index-guided pulmonary vein isolation—markers of arrhythmia recurrence?
BackgroundThere are conflicting data regarding the relationship between high-sensitivity cardiac Troponin I (Hs-cTnI) and the ablation effectiveness...
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DACRA induces profound weight loss, satiety control, and increased mitochondrial respiratory capacity in adipose tissue
Background and objectivesDual amylin and calcitonin receptor agonists (DACRAs) are therapeutic candidates in the treatment of obesity with beneficial...
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Quality of life and healthcare costs of patients with allergic respiratory diseases: a cross-sectional study
BackgroundAllergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this...
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Spatiotemporal variations of “triple-demic” outbreaks of respiratory infections in the United States in the post-COVID-19 era
BackgroundThe US confronted a “triple-demic” of influenza, respiratory syncytial virus (RSV), and COVID-19 in the winter of 2022, leading to...
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Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions
Extracorporeal carbon dioxide removal (ECCO 2 R) is a form of extracorporeal life support (ECLS) largely aimed at removing carbon dioxide in patients...
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Improved oxygenation in prone positioning of mechanically ventilated patients with COVID-19 acute respiratory distress syndrome is associated with decreased pulmonary shunt fraction: a prospective multicenter study
BackgroundProne position is used in acute respiratory distress syndrome and in coronavirus disease 2019 (Covid-19) acute respiratory distress...
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Plasma bioactive adrenomedullin on intensive care unit admission is associated with acute respiratory distress syndrome: an observational study
BackgroundBioactive adrenomedullin (bio-ADM) is a vasoactive peptide with a key role in reducing vascular hyperpermeability and improving endothelial...
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Higher Cumulative Dose of Opioids and Other Sedatives are Associated with Extubation Failure in Norwood Patients
BackgroundThe primary purpose of this study is to evaluate the relationship between sedation usage and extubation failure, and to control for the...
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Physiological response to prone positioning in intubated adults with COVID-19 acute respiratory distress syndrome: a retrospective study
BackgroundCOVID-19 related acute respiratory distress syndrome (ARDS) has specific characteristics compared to ARDS in other populations. Proning is...
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Dead space ventilation-related indices: bedside tools to evaluate the ventilation and perfusion relationship in patients with acute respiratory distress syndrome
Cumulative evidence has demonstrated that the ventilatory ratio closely correlates with mortality in acute respiratory distress syndrome (ARDS), and...
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Lung perfusion during veno-venous extracorporeal membrane oxygenation in a model of hypoxemic respiratory failure
BackgroundVeno-venous extracorporeal membrane oxygenation (ECMO) provides blood oxygenation and carbon dioxide removal in acute respiratory distress...
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Increased Resting Energy Expenditure/Body Weight and Decreased Respiratory Quotient Correlate with Satisfactory Weight Loss After Sleeve Gastrectomy: a 6-Month Follow-Up
BackgroundAlthough bariatric surgery can achieve sustained weight loss, there are major differences in the magnitude of weight change...
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New insights in pediatrics in 2021: choices in allergy and immunology, critical care, endocrinology, gastroenterology, genetics, haematology, infectious diseases, neonatology, neurology, nutrition, palliative care, respiratory tract illnesses and telemedicine
In this review, we report the developments across pediatric subspecialties that have been published in the Italian Journal of Pediatrics in 2021. We...
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Optimizing respiratory management in preterm infants: a review of adjuvant pharmacotherapies
Adjuvant respiratory therapies in preterm neonates aim to reduce long-term morbidities and mortality. Commonly utilized therapies include caffeine,...
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Development of the Birthweight Appropriateness Quotient: A New Measure of Infant’s Size
IntroductionThe customised birthweight model can be used to improve detection of babies that may be at risk of adverse outcomes associated with...