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Comparison of raw and regression approaches to capturing change on patient-reported outcome measures
PurposePatient-reported outcome (PRO) analyses often involve calculating raw change scores, but limitations of this approach are well documented....
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Establishing minimal detectable change thresholds for the international knee documentation committee and Kujala scores at one and two years after patellofemoral joint arthroplasty
PurposeTo define the minimal detectable change (MDC) for the international knee documentation committee (IKDC) and Kujala scores one and two years...
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Quality of life of the Canadian population using the VR-12: population norms for health utility values, summary component scores and domain scores
ObjectivesTo estimate Canadian population norms (health utility values, summary component scores and domain scores) for the VR-12.
Methods ...
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From raw data to a score: comparing quantitative methods that construct multi-level composite implementation strength scores of family planning programs in Malawi
BackgroundData that capture implementation strength can be combined in multiple ways across content and health system levels to create a summary...
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Estimation of place-based vulnerability scores for HIV viral non-suppression: an application leveraging data from a cohort of people with histories of using drugs
The relationships between place (e.g., neighborhood) and HIV are commonly investigated. As measurements of place are multivariate, most studies apply...
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A post hoc analysis of Projected Retained Ability Scores (PRAS) for the longitudinal assessment of cognitive functioning in patients with neuronopathic mucopolysaccharidosis II receiving intrathecal idursulfase-IT
BackgroundNorm-based scores used to assess cognitive ability have clinical value when describing functioning of patients with neuronopathic disorders...
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Population normative data for OxCAP-MH capability scores
AimThe study aims to establish the first set of normative data for OxCAP-MH capability instrument and to examine its association with...
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Machine learning-based health environmental-clinical risk scores in European children
BackgroundEarly life environmental stressors play an important role in the development of multiple chronic disorders. Previous studies that used...
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A first look at the reliability, validity and responsiveness of L-PF-35 dyspnea domain scores in fibrotic hypersensitivity pneumonitis
BackgroundDyspnea impairs quality of life (QOL) in patients with fibrotic hypersensitivity pneumonitis (FHP). The Living with Pulmonary Fibrosis...
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Estimating meaningful change for The Impact of Weight on Self-Perception (IW-SP) questionnaire among people with type 2 diabetes
PurposeThe Impact of Weight on Self-perception Questionnaire (IW-SP) is a three-item patient-reported outcome measure (PROM) instrument assessing the...
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Do preoperative PROMIS scores independently predict 90-day readmission following primary total knee arthroplasty?
IntroductionThe rising demand for total knee arthroplasty (TKA) is expected to increase the total number of TKA-related readmissions, presenting...
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Likely change indexes improve estimates of individual change on patient-reported outcomes
PurposeIndividual change on a patient-reported outcome (PRO) measure can be assessed by statistical significance and meaningfulness to patients. We...
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Disease severity prognostication in primary sclerosing cholangitis: a validation of the Anali scores and comparison with the potential functional stricture
ObjectivesOur aim was twofold. First, to validate Anali scores with and without gadolinium (ANALI Gd and ANALI NoGd ) in primary sclerosing cholangitis...
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Adipose tissue-derived metabolite risk scores and risk for type 2 diabetes in South Asians
BackgroundSouth Asians are at higher risk for type 2 diabetes (T2D) than many other race/ethnic groups. Ectopic adiposity, specifically hepatic...
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Responsiveness and minimal important change of the Family Reported Outcome Measure (FROM-16)
BackgroundThe FROM-16 is a generic family quality of life (QoL) instrument that measures the QoL impact of patients’ disease on their family...
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How Does the New Australian EQ-5D-5L Value Set Impact Utility Scores? Analysis of Data from the Australian Orthopaedic Association National Joint Replacement Registry
BackgroundWith advances in health state valuation methods, new value sets may be developed for some countries. Quantifying the impact of moving...
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Development of a map** function ("crosswalk") for the conversion of scores between the Oswestry Disability Index (ODI) and the Core Outcome Measures Index (COMI)
IntroductionThe Oswestry Disability Index (ODI) and the Core Outcome Measures Index (COMI) are two commonly used self-rating outcome instruments in...
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Predicting cognitive scores from wearable-based digital physiological features using machine learning: data from a clinical trial in mild cognitive impairment
BackgroundContinuous assessment and remote monitoring of cognitive function in individuals with mild cognitive impairment (MCI) enables tracking...
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Normative data beyond the total scores: a process score analysis of the Rey’s 15 word test in healthy aging and Alzheimer’s Disease
BackgroundThe Rey’s 15 words test is currently the most frequently used task in Italy to detect memory deficits in AD. The current standardised...
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Polygenic risk scores of lithium response and treatment resistance in major depressive disorder
Treatment response and resistance in major depressive disorder (MDD) are suggested to be heritable. Due to significant challenges in defining...
