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Coronary CTA-based radiomic signature of pericoronary adipose tissue predict rapid plaque progression
ObjectivesTo explore the value of radiomic features derived from pericoronary adipose tissue (PCAT) obtained by coronary computed tomography...
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Glycemic control is independently associated with rapid progression of coronary atherosclerosis in the absence of a baseline coronary plaque burden: a retrospective case–control study from the PARADIGM registry
BackgroundThe baseline coronary plaque burden is the most important factor for rapid plaque progression (RPP) in the coronary artery. However, data...
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Layered plaque and plaque volume in patients with acute coronary syndromes
BackgroundLayered plaque is a signature of previous subclinical plaque destabilization and healing. Following plaque disruption, thrombus becomes...
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Does Coronary Plaque Morphology Matter Beyond Plaque Burden?
Purpose of ReviewImaging of adverse coronary plaque features by coronary computed tomography angiography (CCTA) has advanced greatly and at a fast...
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Layered plaque is associated with high levels of vascular inflammation and vulnerability in patients with stable angina pectoris
Layered plaque, a signature of previous plaque destabilization and healing, is a known predictor for rapid plaque progression; however, the mechanism...
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Utilizing (serial) coronary computed tomography angiography (CCTA) to predict plaque progression and major adverse cardiac events (MACE): results, merits and challenges
ObjectivesTo present an overview of studies using serial coronary computed tomography angiography (CCTA) as a tool for finding both quantitative...
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Plaque progression at coronary CT angiography links non-alcoholic fatty liver disease and cardiovascular events: a prospective single-center study
ObjectivesThe presence of non-alcoholic fatty liver disease (NAFLD) has been associated with major adverse cardiovascular events (MACEs); however,...
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Atherosclerotic plaque stabilization and regression: a review of clinical evidence
Atherosclerotic plaque results from a complex interplay between lipid deposition, inflammatory changes, cell migration and arterial wall injury. Over...
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The effect of LDL-C status on the association between increased coronary artery calcium score and compositional plaque volume progression in statins-treated diabetic patients: evaluated using serial coronary CTAs
BackgroundIn statins-treated diabetic mellitus (DM) patients, longitudinal coronary CTA (CCTA) evidence is scarce regarding the relationship between...
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Local and systemic factors associated with quantitative stiffness of carotid plaque
PurposePlaque stiffness in carotid artery stenosis is a clinically important factor involved in the development of stroke and surgical complications....
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Macrophage profiling in atherosclerosis: understanding the unstable plaque
The development and rupture of atherosclerotic plaques is a major contributor to myocardial infarctions and ischemic strokes. The dynamic evolution...
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Progression from normal vessel wall to atherosclerotic plaque: lessons from an optical coherence tomography study with follow-up of over 5 years
The initial process of atherosclerotic development has not been systematically evaluated. This study aimed to observe atherosclerotic progression...
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Mzb1 Attenuates Atherosclerotic Plaque Vulnerability in ApoE-/- Mice by Alleviating Apoptosis and Modulating Mitochondrial Function
In this study, we investigated the protective role of Mzb1 in atherosclerotic plaque vulnerability. To explore the impact of Mzb1, we analyzed Mzb1...
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Discrepancy between plaque vulnerability and functional severity of angiographically intermediate coronary artery lesions
This study sought to investigate the relationship between physiological severity and plaque vulnerability of intermediate coronary artery stenoses as...
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Roadmap on the use of artificial intelligence for imaging of vulnerable atherosclerotic plaque in coronary arteries
Artificial intelligence (AI) is likely to revolutionize the way medical images are analysed and has the potential to improve the identification...
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The Efficacy and Safety of Bimekizumab for Plaque Psoriasis: An Expert Consensus Panel
IntroductionPsoriasis is a chronic inflammatory condition affecting the skin, joints, and several other organ systems with significant disease...
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Tapinarof Cream 1% Once Daily for the Treatment of Plaque Psoriasis: Case Photography of Clinical Outcomes from Three Phase 3 Trials
Tapinarof cream 1% (VTAMA ® ; Dermavant Sciences, Inc.) is a non-steroidal, topical, aryl hydrocarbon receptor agonist approved by the US Food and Drug...
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High-Risk Coronary Plaque Features: A Narrative Review
Advances in coronary plaque imaging over the last few decades have led to an increased interest in the identification of novel high-risk plaque...
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Incremental value of enhanced plaque length for identifying intracranial atherosclerotic culprit plaques: a high-resolution magnetic resonance imaging study
ObjectivesBesides plaque enhancement grade, the incremental value of enhancement-related high-resolution MRI features in defining culprit plaques...
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Serial analysis of coronary artery disease progression by artificial intelligence assisted coronary computed tomography angiography: early clinical experience
BackgroundStudies have shown that quantitative evaluation of coronary artery plaque on Coronary Computed Tomography Angiography (CCTA) can identify...