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1. Effects of Ultraviolet B Radiation on the Function of the Testicles, Expression of Caspase-3 and NOS-2, and the Protective Role of Naringin in Mice

   In today’s evolving global environment, reproductive dysfunctions brought on by various environmental toxins are of greatest concern. Radiation is a...

   Shashank Shakyawal, Narendra Namdev, ... Payal Mahobiya in Reproductive Sciences

   Article 09 October 2023
   

2. Thymoquinone effects on autophagy, apoptosis, and oxidative stress in cisplatin-induced testicular damage in mice

   Purpose

   In this study, the effect of thymoquinone (TQ) on CP-induced spermatogenesis defects in mice has been investigated.

   Methods

   Sperm parameters,...

   Mina Shojaedini, Masoud Hemadi, ... Layasadat Khorsandi in Journal of Assisted Reproduction and Genetics

   Article 03 April 2024
   

3. Early and Accurate Detection of Radiation-induced Heart Damage by Cardiodynamicsgram

   Cardiodynamicsgram (CDG) has emerged recently as a noninvasive spatiotemporal electrocardiographic method for subtle cardiac dynamics information...

   Yuanyuan Tao, Qinghua Sun, ... Shuanghu Yuan in Journal of Cardiovascular Translational Research

   Article 07 August 2023
   

4. A perspective on tumor radiation resistance following high-LET radiation treatment

   High-linear energy transfer (LET) radiation is a promising alternative to conventional low-LET radiation for therapeutic gain against cancer owing to...

   Yogendra Singh Rajpurohit, Dhirendra Kumar Sharma, ... Ishu Soni in Journal of Cancer Research and Clinical Oncology

   Article Open access 02 May 2024
   

5. GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

   In the treatment of most malignancies, radiotherapy plays a significant role. However, the resistance of cancer cells to ionizing radiation (IR) is...

   Yao Long, Jiaxing Guo, ... Yongguang Tao in Signal Transduction and Targeted Therapy

   Article Open access 01 February 2023
   

6. Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice

   Objective

   Assessing the advantage of x-ray dark-field contrast over x-ray transmission contrast in radiography for the detection of develo**...

   Rico Burkhardt, Thomas Gora, ... Julia Herzen in European Radiology

   Article Open access 19 November 2020
   

7. Early detection of radiation-induced myocardial damage by [¹⁸F]AlF-NOTA-FAPI-04 PET/CT imaging

   Purpose

   Retrospective analysis revealed increased [ ¹⁸ F]AlF-NOTA-FAPI-04 uptake in the myocardium of patients with esophageal squamous cell cancer...

   Yuchun Wei, Yuhong Sun, ... **ming Yu in European Journal of Nuclear Medicine and Molecular Imaging

   Article 19 September 2022
   

8. Polydatin radiosensitizes lung cancer while preventing radiation injuries by modulating tumor-infiltrating B cells

   Background

   Acquired radio-resistance and the undesired normal tissue radiation injuries seriously discount the therapeutic effect of lung cancer...

   Jiaming Guo, Wen Ding, ... Jianming Cai in Journal of Cancer Research and Clinical Oncology

   Article Open access 23 May 2023
   

9. Crosstalk between immune checkpoint and DNA damage response inhibitors for radiosensitization of tumors

   Purpose

   This review article is intended to provide a perspective overview of potential strategies to overcome radiation resistance of tumors through...

   Sandra Classen, Cordula Petersen, Kerstin Borgmann in Strahlentherapie und Onkologie

   Article Open access 07 July 2023
   

10. Deep learning automatically assesses 2-µm laser-induced skin damage OCT images

    The present study proposed a noninvasive, automated, in vivo assessment method based on optical coherence tomography (OCT) and deep learning...

    Changke Wang, Qiong Ma, ... Hongxiang Kang in Lasers in Medical Science

    Article 18 April 2024
    

11. Evolution of radiation-induced dermatitis treatment

    Radiation-induced skin damage (RID) is the most prevalent, significant side effect of radiotherapy (RT). Nearly 95% of patients experience moderate...

    Deng Guangmei, He Weishan, ... Chen Jibing in Clinical and Translational Oncology

    Article 09 April 2024
    

12. Downregulation of CEMIP enhances radiosensitivity by promoting DNA damage and apoptosis in colorectal cancer

    Colorectal cancer (CRC) is the third leading malignancy worldwide in both new cases and deaths. Neoadjuvant radiotherapy is the standard preoperative...

    Jiawen Weng, Yuqin Zhang, ... Yiyi Li in Medical Oncology

    Article 06 January 2023
    

13. Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury

    Background

    Radiation-induced lung injury (RILI) is the most common and serious complication of chest radiotherapy. However, reported radioprotective...

    **nrui Rao, Dong Zhou, ... Rui Zhou in Respiratory Research

    Article Open access 24 January 2023
    

14. Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape

    Background

    Radiation nanomedicines are nanoparticles labeled with radionuclides that emit α- or β-particles or Auger electrons for cancer treatment....

    Raymond M. Reilly, Constantine J. Georgiou, ... Zhongli Cai in EJNMMI Radiopharmacy and Chemistry

    Article Open access 04 May 2024
    

15. Pathological consequences of DNA damage in the kidney

    DNA lesions that evade repair can lead to mutations that drive the development of cancer, and cellular responses to DNA damage can trigger senescence...

    Juan I. Garaycoechea, Catherine Quinlan, Martijn S. Luijsterburg in Nature Reviews Nephrology

    Article 26 January 2023
    

16. Andrographolide protects acute ultraviolet-B radiation-induced photodamages in the mouse skin

    This study evaluates the preventive role of andrographolide (ADP) against ultraviolet-B (UVB) radiation-induced photoaging in the mouse skin. Grouped...

    R. Indirapriyadarshini, G. Kanimozhi, ... Sathiya Jeeva Jeevakaruniyam in Archives of Dermatological Research

    Article 10 December 2022
    

17. Aurora Kinase A inhibition enhances DNA damage and tumor cell death with ¹³¹I-MIBG therapy in high-risk neuroblastoma

    Background

    Neuroblastoma is the most common extra-cranial pediatric solid tumor.  ¹³¹ I-metaiodobenzylguanidine (MIBG) is a targeted...

    Prerna Kumar, Jessica Koach, ... Youngho Seo in EJNMMI Research

    Article Open access 13 June 2024
    

18. miR-4796 enhances the sensitivity of breast cancer cells to ionising radiation by impairing the DNA repair pathway

    Background

    MicroRNAs (miRNAs) are important regulators of DNA damage response (DDR) through post-transcriptional regulation on their target genes,...

    Ting Jiang, **feng Chen, ... Yanke Chen in Breast Cancer

    Article 17 July 2023
    

19. Increased [¹⁸F]FDG uptake of radiation-induced giant cells: a single-cell study in lung cancer models

    Positron emission tomography (PET), a cornerstone in cancer diagnosis and treatment monitoring, relies on the enhanced uptake of fluorodeoxyglucose ([

    Neeladrisingha Das, Hieu T. M. Nguyen, ... Guillem Pratx in npj Imaging

    Article Open access 19 June 2024
    

20. New Insights into the Understanding of Mechanisms of Radiation-Induced Heart Disease

    Cancer patients who receive high-dose thoracic radiotherapy may develop radiation-induced heart disease (RIHD). The clinical presentation of RIHD...

    Kai-Xuan Wang, Cong Ye, ... Lan Luo in Current Treatment Options in Oncology

    Article 04 January 2023