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Refractory pure red cell aplasia associated with T-cell large granular lymphocyte leukemia treated by ruxolitinib
Acquired pure red cell aplasia (PRCA) is a rare syndrome characterized by normocytic normochromic anemia with severe reticulocytopenia and absence of...
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STK10 mutations block erythropoiesis in acquired pure red cell aplasia via impairing ribosome biogenesis
Acquired pure red cell aplasia (PRCA) is anemia associated with the absence of erythroblasts and is characterized by persistent and easy recurrence....
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Gilteritinib combined with venetoclax and azacitidine for relapsed acute myeloid leukemia cocurrent with pure red cell aplasia after allogeneic hematopoietic stem cell transplantation: a case report
Pure red cell aplasia (PRCA) is a rare bone marrow (BM) disorder characterized by ineffective erythropoiesis, reduced reticulocyte count, normocytic...
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Positive response of a hemodialysis patient with pure red cell aplasia on recombinant human erythropoietin therapy to cyclosporine and Roxadustat
Recombinant human erythropoietin (rHuEPO) is commonly used to treat anemia associated with chronic kidney disease (CKD). EPO-induced Pure Red Cell...
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A nomogram model for predicting the efficacy of cyclosporine in patients with pure red cell aplasia
Pure red cell aplasia (PRCA) is a rare bone marrow disorder characterized by a severe reduction or absence of erythroid precursor cells, without...
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A pregnant woman with thymoma-associated pure red cell aplasia
BackgroundPure red cell aplasia (PRCA) is a hematological disorder characterized by anemia with severe reticulocytopenia caused by a marked reduction...
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Waldenström macroglobulinemia with secondary pure red cell aplasia in a patient with metastatic castrate resistant prostate cancer receiving an immune checkpoint inhibitor: a case report
BackgroundHypoproliferative anemia is a frequently encountered adverse event in cancer patients receiving immune checkpoint inhibitors (ICI)....
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High TOX expression on CD8+ T cells in pure red cell aplasia
Thymocyte selection-associated high-mobility group box protein (TOX) is an important molecule regulating the development and exhaustion of T...
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Acquired pure red cell aplasia after severe acute respiratory syndrome corona virus 2 infection: a case report
BackgroundCoronavirus disease 2019, caused by severe acute respiratory coronavirus 2, has been responsible, since December 2019, for a severe...
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Clinical characteristics and outcomes of 100 adult patients with pure red cell aplasia
Adult pure red cell aplasia (PRCA) is a rare syndrome characterized by a severe normocytic anemia, reticulocytopenia, and absence of erythroblasts...
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Immune reconstitution and survival of patients with parvovirus B19 related pure red cell aplasia after haplo-PBSCT
Parvovirus B19 (PvB19) infection and PvB19 related pure red cell aplasia (PRCA) in recipients with allogeneic hematopoietic stem cell transplantation...
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T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia
Acquired chronic pure red cell aplasia (PRCA) develops idiopathically or in association with other medical conditions, including T cell large...
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Minimally invasive extended thymectomy for thymoma associated with pure red cell aplasia
Anaemia characterised by near absence of red cell precursors in the bone marrow is referred to as “pure red cell aplasia (PRCA).” It has an unusual...
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Pure red cell aplasia secondary to rheumatoid arthritis: a case report
BackgroundRheumatoid arthritis is a common autoimmune disease with many extra-articular manifestations. Pure red cell aplasia is a rare manifestation...
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Sirolimus is effective for refractory/relapsed/intolerant acquired pure red cell aplasia: results of a prospective single-institutional trial
Some patients with acquired pure red cell aplasia (aPRCA) have no response or are intolerant to cyclosporine A. From April 2017 to August 2020,...
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Eltrombopag restores erythropoiesis in refractory adult acquired pure red cell aplasia
Acquired pure red cell aplasia is a rare condition characterized by normocytic normochromic anemia with severe reticulocytopenia. In refractory...
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Pure red cell aplasia after major or bidirectional ABO incompatible hematopoietic stem cell transplantation: to treat or not to treat, that is the question
Pure red cell aplasia (PRCA) is a complication related to major or bidirectional ABO mismatched hematopoietic stem cell transplantation. This...