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Agomelatine augmentation of sertraline in the treatment of moderate to severe obsessive-compulsive disorder: a randomized double-blinded placebo-controlled clinical trial
BackgroundAs 40–60% of the patients with obsessive-compulsive disorder (OCD) do not adequately respond to the first-line treatment, finding an...
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Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (OCD) can be considered an...
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Focused ultrasound for functional neurosurgery
IntroductionBrain lesioning is a fundamental technique in the functional neurosurgery world. It has been investigated for decades and presented...
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Self-injurious behavior in Tourette syndrome
IntroductionTourette syndrome (TS) is characterized by the presence of motor and phonic tics, as well as a variety of behavioral co-morbidities....
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Memantine augmentation of sertraline in the treatment of symptoms and executive function among patients with obsessive-compulsive disorder: A double-blind placebo-controlled, randomized clinical trial
BackgroundMedications currently recommended for the treatment of Obsessive-Compulsive Disorder (OCD) usually decrease the severity of the symptoms by...
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Consensus recommendations for the assessment and treatment of perinatal obsessive–compulsive disorder (OCD): A Delphi study
The perinatal period is one of increased vulnerability to parents experiencing the onset of, or an increase of existing, obsessive–compulsive...
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Reader comments to media reports on psychiatric neurosurgery: past history casts shadows on the future
BackgroundComments made by readers in response to news articles about current events can provide profound insights into public understanding of and...
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Cognitive outcomes following functional neurosurgery in refractory OCD patients: a systematic review
Neurosurgery is a therapeutic option for patients with refractory obsessive–compulsive disorder who do not respond to previous treatments. Although...
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White matter microstructural and morphometric alterations in autism: implications for intellectual capabilities
BackgroundNeuroimage literature of autism spectrum disorder (ASD) has a moderate-to-high risk of bias, partially because those combined with...
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The impact of preoperative anxiety on patients undergoing brain surgery: a systematic review
Preoperative anxiety is a common reaction exhibited by up to 80% of patients who are scheduled for surgical procedures and characterized by...
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Quality of mental health services and rights of people receiving treatment in inpatient services in Finland: a cross-sectional observational survey with the WHO QualityRights Tool Kit
BackgroundThis article aims to review the quality of mental health services and the rights of the people receiving treatment in inpatient hospital...
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Feasibility and acceptability of transcranial stimulation in obsessive–compulsive symptoms (FEATSOCS): study protocol for a randomised controlled trial of transcranial direct current stimulation (tDCS) in obsessive–compulsive disorder (OCD)
BackgroundObsessive–compulsive disorder (OCD) is a neuropsychiatric disorder which often proves refractory to current treatment approaches....
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The prefrontal cortex and neurosurgical treatment for intractable OCD
Over the past two decades, circuit-based neurosurgical procedures have gained increasing acceptance as a safe and efficacious approach to the...
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Deep brain stimulation of the “medial forebrain bundle”: a strategy to modulate the reward system and manage treatment-resistant depression
The medial forebrain bundle—a white matter pathway projecting from the ventral tegmental area—is a structure that has been under a lot of scrutinies...
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Perceptions of free will in obsessive-compulsive disorder: a quantitative analysis
BackgroundThe aim of this study was to explore perceptions of free will in the repetitive behaviors of patients with obsessive-compulsive disorder...
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The re-emergence of psychiatric neurosurgery: insights from a cross-national study of newspaper and magazine coverage
BackgroundSurgical approaches to treat psychiatric disorders have made a comeback. News media plays an essential role in exposing the public to...
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Patient-Reported Satisfaction Following Post-bariatric Surgery: A Systematic Review
IntroductionThe aims of our study were to identify studies that evaluated patient satisfaction following post-bariatric surgery, analyse existing...
