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  1. Prothrombin complex concentrate (PCC) for treatment of trauma-induced coagulopathy: systematic review and meta-analyses

    Background

    Trauma-induced coagulopathy (TIC) is common in trauma patients with major hemorrhage. Prothrombin complex concentrate (PCC) is used as a...

    Ioannis Hannadjas, Arthur James, ... Elaine Cole in Critical Care
    Article Open access 02 November 2023
  2. Four-factor prothrombin complex concentrate in trauma patients

    Pierre Bouzat, Beverley J. Hunt, Nicole P. Juffermans in Intensive Care Medicine
    Article 24 July 2023
  3. Andexanet alpha versus four-factor prothrombin complex concentrate in DOACs anticoagulation reversal: an updated systematic review and meta-analysis

    Background

    There is currently a lack of evidence for the comparative effectiveness of Andexanet alpha and four-factor prothrombin complex concentrate...

    Daniele Orso, Federico Fonda, ... Tiziana Bove in Critical Care
    Article Open access 05 July 2024
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