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Occupational disease predictors in the nickel pyrometallurgical production: a prospective cohort observation
BackgroundPyrometallurgical nickel production exposes workers to a wide range of occupational risk factors, including nickel aerosol, occupational...
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Efficacy of chidamide maintenance therapy versus autologous stem cell transplantation versus observation as a post-remission choice in the survival of adult patients with peripheral T-cell lymphoma: Post hoc analysis of a prospective, multicenter, phase 2 study in China
In this prospective, multicenter, Phase 2 clinical trial (NCT02987244), patients with peripheral T-cell lymphomas (PTCLs) who had responded to...
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Usefulness of the 4A’s test for detecting delirium in critically ill patients: a multicenter prospective observation study
The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) is a robust and reliable instrument for discerning delirium within the specific...
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Observation and assessment of the immediate use of a silicon hydrogel contact lens after transepithelial corneal cross linking: a prospective study
BackgroundTransepithelial corneal crosslinking (CXL) is a novel surgical approach for the treatment of keratoconus, which is a bilateral asymmetrical...
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Observation on clinical effect of Huoxue-Jiangtang decoction formula granules in treating prediabetes: a randomized prospective placebo-controlled double-blind trial protocol
BackgroundPrediabetes is a hypermetabolic syndrome with blood sugar levels falling between the normal and diabetes. People with prediabetes have a...
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Survival Analysis and Immune Differences of HIV Long-Term Non-progressors in **njiang China: A 12-Year Prospective Cohort Observation
This 12-year cohort study of 80 long-term non-progressors (LTNPs) observed a cumulative follow-up duration of 628.5 person-years. Among them, 60...
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Increased medial talar tilt may incite ankle pain and predispose ankle osteoarthritis after correction of severity of knee varus deformity among patients undergoing bilateral total knee arthroplasty: a prospective observation
PurposePatients with varus knee osteoarthritis usually compensate at the ankle and typically walk with hindfoot valgus alignment. As the neutral...
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Regional Nodal Recurence as a Prognostic Factor in Patients Kept on Observation for cT1–T2 Oral Squamous Cell Carcinomas of Tongue: A Meta-Analysis of 11,973 Patients
The surgical management of the clinically node negative neck in T1–T2 early oral tongue squamous cell carcinoma (OTSCC) has been the topic of debate...
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BMI trajectories, associations with outcomes and predictors in elderly gastric cancer patients undergoing radical gastrectomy: a prospective longitudinal observation study
ObjectivesElderly gastric cancer patients undergoing radical gastrectomy are prone to experience unexpected weight loss. Preoperative weight risk...
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Observation on the effectiveness and safety of sodium bicarbonate Ringer’s solution in the early resuscitation of traumatic hemorrhagic shock: a clinical single-center prospective randomized controlled trial
BackgroundTraumatic hemorrhagic shock (THS) is the main cause of death in trauma patients with high mortality. Rapid control of the source of...
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Optimal fracture prediction thresholds for therapy onset, established from FRAX and Garvan algorithms: a longitudinal observation of the population representative female cohort from the RAC-OST-POL Study
SummaryThe study shows that the use of unified cutoff thresholds to identify high fracture risks by two popular calculators—FRAX and Garvan—leads to...
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A PrOsPective Cohort Study on Interstitial Lung Disease-Associated Pulmonary Hypertension with a ParticulaR Focus on the Subset with Pulmonary Arterial Hypertension Features (POPLAR Study)
IntroductionThe pathogenesis and clinical profiles of patients with pulmonary hypertension (PH) associated with interstitial lung disease (ILD-PH)...
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Urinary pentosidine level is associated with the risk of fracture in community-dwelling older adults: a prospective observational study
SummaryA history of fracture in adulthood and urinary pentosidine levels were independently and significantly associated with fracture occurrence in...
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Young children with a minor traumatic head injury: clinical observation or CT scan?
Currently, in young children with minor traumatic head injuries (MTHI) classified as intermediate risk (IR), PECARN recommends clinical observation...
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Observation, laser photocoagulation or anti-VEGF therapy in the management of retinal arterial macroaneurysms
BackgroundTo explore the efficacy of observation, laser photocoagulation, and anti-VEGF in the management of retinal arterial macroaneurysm (RAM).
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Comparison of pregnancy and neonatal outcomes in a retrospective full pregnancy history survey versus population-based prospective records: a validation study in rural Sarlahi District, Nepal
IntroductionCountries without complete civil registration and vital statistics systems rely on retrospective full pregnancy history surveys (FPH) to...
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Sentinel lymph node biopsy versus observation in high risk cutaneous squamous cell carcinoma of head and neck: a propensity score matching analysis
Sentinel lymph node biopsy (SLNB) has gained considerable attention in the management of head and neck cutaneous squamous cell carcinoma (HNcSCC)....
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Causal impact of DNA methylation on refracture in elderly individuals with osteoporosis – a prospective cohort study
BackgroundOsteoporotic vertebral compression fractures (OVCF) in the elderly increase refracture risk post-surgery, leading to higher mortality...
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Patient-reported outcome measures more than fifteen years after treatment of sagittal or metopic craniosynostosis: a prospective cohort study
PurposeTo evaluate the long-term anthropometric measurements, cosmetic satisfaction, and other patient-reported outcome measures (PROMs) of patients...
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Potential Role for Observation in Small Solid Pseudopapillary Neoplasm (SPN)
BackgroundSolid pseudopapillary neoplasms (SPN) are rare tumors of the pancreas, typically affecting young women. Resection is the mainstay of...
