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Multi-omics approaches identify novel prognostic biomarkers of autophagy in uveal melanoma
PurposeUveal melanoma (UVM) is a rare yet malignant ocular tumor that metastases in approximately half of all patients, with the majority of those...
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Multiple machine-learning tools identifying prognostic biomarkers for acute Myeloid Leukemia
BackgroundAcute Myeloid Leukemia (AML) generally has a relatively low survival rate after treatment. There is an urgent need to find new biomarkers...
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Systemic inflammatory biomarkers as prognostic tools in patients with gastroesophageal adenocarcinoma
PurposeGastroesophageal adenocarcinoma is associated with poor prognosis, even in resectable stages. Systemic inflammation plays a key role in cancer...
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Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma
The therapeutic algorithm of renal cell carcinoma has been revolutionized by the approval of immunotherapy agents by regulatory agencies. However,...
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Single-cell RNA-Seq and bulk RNA-Seq reveal reliable diagnostic and prognostic biomarkers for CRC
PurposeThe potential role of epithelium-specific genes through the adenoma-carcinoma sequence in the development of colorectal cancer (CRC) remains...
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Prognostic models predicting transition to psychotic disorder using blood-based biomarkers: a systematic review and critical appraisal
Accumulating evidence suggests individuals with psychotic disorder show abnormalities in metabolic and inflammatory processes. Recently, several...
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Metabolomics and machine learning approaches for diagnostic and prognostic biomarkers screening in sepsis
BackgroundSepsis is a life-threatening disease with a poor prognosis, and metabolic disorders play a crucial role in its development. This study aims...
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The role of diagnostic, prognostic, and predictive biomarkers in the management of early pancreatic cancer
Despite modern advances in cancer medicine, pancreatic cancer survival remains unchanged at just 12%. For the small proportion of patients diagnosed...
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Identification of prognostic and therapeutic biomarkers in type 2 papillary renal cell carcinoma
BackgroundPapillary renal cell carcinoma (PRCC) can be divided into type 1 (PRCC1) and type 2 (PRCC2) and PRCC2 share a more invasive phenotype and...
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Circulating MicroRNAs as Noninvasive Diagnostic and Prognostic Biomarkers in Pancreatic Cancer: A Review
Pancreatic cancer (PC) is one of the most lethal human cancers. Currently, most PC cases are diagnosed at an already advanced stage. Early detection...
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Identification of m6A-associated genes as prognostic and immune-associated biomarkers in Wilms tumor
ObjectivesWilms tumor (WT) is a common renal malignant tumor in children. We aimed to investigate the potential prognostic value of m6A-related genes...
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Molecular profiling and prognostic biomarkers in chinese non-small cell lung cancer cohort
IntroductionComprehensive information about the genome analysis and its prognostic values of NSCLC patients in Chinese population are still needed.
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Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling
Molecular targets and predictive biomarkers for prognosis in salivary duct carcinoma (SDC) have not been fully identified. We conducted comprehensive...
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Exosomes and cancer - Diagnostic and prognostic biomarkers and therapeutic vehicle
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic multistep endocytosis process and carry diverse functional...
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Ferroptosis-related genes prognostic signature for pancreatic cancer and immune infiltration: potential biomarkers for predicting overall survival
BackgroundPancreatic adenocarcinoma (PAAD) constitutes a lethal malignancy, notorious for its elevated mortality rates due to the difficulties in...
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Decoding the regulatory landscape of lncRNAs as potential diagnostic and prognostic biomarkers for gastric and colorectal cancers
Colorectal cancer (CRC) and gastric cancer (GC) are major contributors to cancer-related mortality worldwide. Despite advancements in understanding...
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Endoplasmic reticulum stress-related genes as prognostic and immunogenic biomarkers in prostate cancer
BackgroundThe metastasis and aggressive nature of prostate cancer (PCa) has become a major malignancy related threat that concerns men’s health. The...
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Biological Clock Genes are Crucial and Promising Biomarkers for the Therapeutic Targets and Prognostic Assessment in Gastric Cancer
BackgroundGastric cancer is one of the major public health problems worldwide. Circadian rhythm disturbances driven by circadian clock genes play a...
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CENPE and LDHA were potential prognostic biomarkers of chromophobe renal cell carcinoma
BackgroundMost sarcomatoid differentiated renal cell carcinoma was differentiated from Chromophobe renal cell carcinoma (KICH) and related to a bad...
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SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer
BackgroundImmune cells and stromal cells in the tumor microenvironment play a vital role in the progression of colorectal cancer (CRC). The study...
