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Multiple exposures to heavy metals and changes in steroid hormones production in 4-year-old children
BackgroundPrenatal exposure to multiple heavy metals can interfere with early neurodevelopment, lead to changes in sex hormone concentrations in...
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Sex-specific and sex-independent steroid-related biomarkers in early second trimester maternal serum associated with autism
BackgroundPrenatal exposure to maternal metabolic conditions associated with inflammation and steroid dysregulation has previously been linked to...
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Steroid hormone pathways, vitamin D and autism: a systematic review
The origins of the male preponderance in autism incidence remain unclear. The idea that perinatal factors associated with sex differentiation (e.g.,...
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Toxic effect window of ovarian development in female offspring mice induced by prenatal prednisone exposure with different doses and time
BackgroundPrednisone is one of the most used synthetic glucocorticoids during pregnancy. Epidemiological investigations suggested that prenatal...
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Neonatal outcomes of preterm infants with pulmonary hypertension: clustering based on prenatal risk factors
BackgroundTo investigate association of prenatal risk factors and neonatal outcomes of preterm infants with pulmonary hypertension (PH).
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Management of neonates with maternal prenatal coronavirus infection and influencing factors
AbstractThe coronavirus disease 2019 (COVID-19) in pregnancy causes adverse outcomes for both the mother and the fetus. Neonates are at risk of...
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Associations between neighborhood stress and maternal sex steroid hormones in pregnancy
BackgroundNeighborhood stressors (e.g., crime and deprivation) have been associated with adverse pregnancy outcomes including preterm birth and low...
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The effect of steroid administration on fetal diaphragm function
BackgroundAntenatal steroid administrations lead to not only accelerated lung maturation, improved blood gas measurements but also lung dynamics and...
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Prenatal exposure to common plasticizers: a longitudinal study on phthalates, brain volumetric measures, and IQ in youth
Exposure to phthalates, used as plasticizers and solvents in consumer products, is ubiquitous. Despite growing concerns regarding their...
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Prenatal, newborn and childhood factors and the timing of puberty in boys and girls
BackgroundOur aim was to determine if prenatal factors, gestational age, birth weight and length, and childhood body mass index (BMI) are associated...
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Prenatal ultrasound, magnetic resonance imaging and therapeutic options for fetal thoracic anomalies: a pictorial essay
Congenital thoracic anomalies are uncommon malformations that require a precise diagnosis to guide parental counseling and possible prenatal...
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Egyptian pediatric clinical practice adapted guidelines: evidence-based [2] steroid-resistant nephrotic syndrome (SRNS) 2022
BackgroundNephrotic syndrome is one of the most common chronic kidney diseases in children. Steroid sensitive type (SSNS) constitutes about 85–90%,...
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Impact of prenatal, neonatal, and postnatal factors on epilepsy risk in children and adolescents: a systematic review and meta-analysis
BackgroundEpilepsy is a common, long-term neurological condition. Several previous case-control, cohort and cross-sectional studies have highlighted...
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Sex-specific association between prenatal androgenization (second-to-fourth digit length ratio) and frontal brain volumes in adolescents
Prenatal androgenization associates sex-dependently with behavior and mental health in adolescence and adulthood, including risk-taking,...
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A Reduction in Antenatal Steroid Dose Was Associated with Reduced Cardiac Dysfunction in a Sheep Model of Pregnancy
Despite widespread use, dosing regimens for antenatal corticosteroid (ACS) therapy are poorly unoptimized. ACS therapy exerts a programming effect on...
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Prenatal ultrasound screening and pregnancy outcomes in HIV-positive women in Germany: results from a retrospective single-center study at the Charité-Universitätsmedizin Berlin
ObjectivesThe aim of this study was to investigate the rate of Mother-to-child-transmission (MTCT) in women living with HIV (WLWH) in a tertiary care...
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Clinical spectrum of female genital malformations in prenatal diagnosis
IntroductionFetal genital malformations represent a rare and heterogeneous group of congenital malformations of the disorders of sexual development...
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Endocrine effect of phthalate metabolites and a butterfly effect of prenatal exposure to androgens on qualitative aspects of female sexual response- an initial survey
There is growing evidence that endocrine disruptive chemicals have deleterious effects on sexual and reproductive function. To examine subjective...
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Causal and putative pathogenic mutations identified in 39% of children with primary steroid-resistant nephrotic syndrome in South Africa
There is a paucity of data identifying genetic mutations that account for the high rate of steroid-resistant nephrotic syndrome (SRNS) in a South...
