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Effects of a lifestyle intervention on cardiovascular risk factors in systemic lupus erythematosus patients: The study “Living well with lupus”
ObjectiveThe aim of the present study was to investigate the effects of a lifestyle intervention on cardiometabolic risk factors in patients with...
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Nuclear magnetic resonance-determined lipoprotein profile and risk of breast cancer: a Mendelian randomization study
PurposeWhile crudely quantified lipoproteins have been reported to affect the risk of breast cancer, the effects of subclass lipoproteins...
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Associations of perfluoroalkyl substances (PFAS) with lipid and lipoprotein profiles
BackgroundPerfluoroalkyl substances (PFAS) are man-made chemicals with unique properties that are widely distributed in humans and the environment....
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Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study
BackgroundAtherosclerotic vascular diseases are a leading global cause of morbidity and mortality. Dyslipidemia, a major modifiable risk factor for...
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Metabolic dysfunction-associated steatotic liver disease and atherosclerosis
Purpose of reviewTo update information about the relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and...
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Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults
BackgroundThe Uganda Ministry of Health issued restrictive guidelines on the use of dolutegravir (DTG) in persons stratified to have a heightened...
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Overexpression of miR-22-3p and miR-29c-3p in CFU-Hill colonies is related to senescence process among children with low birth weight
BackgroundThe current study mainly focused on provide further insights into the association of the miR-22-3p and miR-29c-3p expression in CFU-Hill...
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The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis
Calcific aortic valve disease (CAVD) and stenosis have a complex pathogenesis, and no therapies are available that can halt or slow their...
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Remnant cholesterol for the detection of glucose metabolic states in patients with coronary heart disease angina pectoris
BackgroundThis study aimed to evaluate the relationship between remnant cholesterol (RC) and glucose metabolic states in coronary heart disease (CHD)...
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Remnant cholesterol is associated with hip BMD and low bone mass in young and middle-aged men: a cross-sectional study
PurposeRemnant cholesterol (RC) is a contributor to cardiovascular diseases, obesity, diabetes, and metabolic syndrome. However, the specific...
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Longitudinal associations between cardiovascular biomarkers and metabolic syndrome during puberty: the PUBMEP study
Puberty has been described as a life stage of considerable metabolic risk specially for those with obesity. The low-grade systemic inflammatory...
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Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity
BackgroundTo describe ethnic differences in concentrations of lipids and lipoproteins, and their changes, during pregnancy to postpartum.
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Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis
Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms....
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Free Cholesterol Bioavailability and Atherosclerosis
Purpose of ReviewAs both a cholesterol acceptor and carrier in the reverse cholesterol transport (RCT) pathway, high-density lipoprotein (HDL) is...
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A Clinical Prediction Model for Patients with Acute Large Vessel Occlusion Due to Underlying Intracranial Atherosclerotic Stenosis
BackgroundAcute large vessel occlusion due to underlying intracranial atherosclerotic stenosis (ICAS-LVO) increases the difficulty of...
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The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT)
Aims/hypothesisHigh-throughput metabolomics technologies in a variety of study designs have demonstrated a consistent metabolomic signature of...
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Maternal lipid profile in pregnancy and embryonic size: a population-based prospective cohort study
BackgroundLipids are crucial for fetal growth and development. Maternal lipid concentrations are associated with fetal growth in the second and third...
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Hepatic insulin resistance and muscle insulin resistance are characterized by distinct postprandial plasma metabolite profiles: a cross-sectional study
BackgroundTissue-specific insulin resistance (IR) predominantly in muscle (muscle IR) or liver (liver IR) has previously been linked to distinct...
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Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics
Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD),...
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Circulating non-coding RNA biomarkers of endocrine tumours
Circulating non-coding RNA (ncRNA) molecules are being investigated as biomarkers of malignancy, prognosis and follow-up in several neoplasms,...