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Serum proteome analysis identifies a potential biomarker for axial psoriatic arthritis
BackgroundTo identify potential serum biomarkers for differentiating between axial psoriatic arthritis (axPsA) and peripheral psoriatic arthritis...
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Circulating acetylcholine serves as a potential biomarker role in pulmonary hypertension
BackgroundAn increased acetylcholine (ACh) level in the right ventricle tissue of pulmonary hypertension (PH) was revealed, which indicated the...
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COX5A as a potential biomarker for disease activity and organ damage in lupus
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease with limited therapeutic targets or clinical outcome predictors. This study aimed...
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Milk miRNA expression in buffaloes as a potential biomarker for mastitis
BackgroundBuffaloes have the highest potential for production due to a promising gene pool that is being enhanced and upgraded. Mastitis is a...
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Exosomal microRNAs in Parkinson’s disease: insights into biomarker potential and disease pathology
Parkinson’s disease (PD) is a prevalent neurodegenerative condition primarily affecting the elderly population. Despite its high incidence in aged...
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Inter-alpha-trypsin inhibitor heavy chain H3 is a potential biomarker for disease activity in myasthenia gravis
Myasthenia gravis is a chronic antibody-mediated autoimmune disease disrupting neuromuscular synaptic transmission. Informative biomarkers remain an...
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DNA methylation of IFI44L as a potential blood biomarker for childhood-onset systemic lupus erythematosus
BackgroundIFN-induced protein 44-like ( IFI44L ) promoter methylation has been demonstrated to serve as an effective blood diagnostic biomarker for...
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Serum THBS2 is a potential biomarker for the diagnosis of non-small cell lung cancer
ObjectiveThis study primarily aimed to analyze the levels of THBS2 in the serum of patients diagnosed with non-small cell lung cancer (NSCLC), and...
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Prokineticin 2 as a potential biomarker for the diagnosis of Kawasaki disease
Kawasaki disease is a pressing acute self-limiting inflammatory disorder disease which lack of specific biomarkers. Our research aims to investigate...
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Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis
Coronary atherosclerosis leading to ischemic artery disease is one of the etiological factors to develop heart failure (HF). This study aimed to...
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MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with hyperactive innate and adaptive immune systems that cause dermatological,...
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Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target
Prostate cancer (CaP) is the most diagnosed cancer in males and the second leading cause of cancer deaths. Patients with localized tumors are...
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Evaluation of the serum tRNA-derived fragment tRF-5022B as a potential biomarker for the diagnosis of osteoarthritis
Osteoarthritis (OA) is a degenerative disease. It is common in middle-aged and elderly people and is one of the main causes of disability. Currently,...
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Proline-Rich Protein 11 Overexpression in Invasive Breast Carcinoma: A Potential Diagnosis Biomarker
PurposeThis study aims to investigated the expression of proline-rich protein 11 (PRR11) as a diagnostic biomarker of invasive breast cancer and to...
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Follistatin-like 1 (FSTL1) levels as potential early biomarker of cardiovascular disease in a Mexican population
Cardiovascular diseases (CVD) are the leading cause of death globally. In recent years, follistatin-like protein 1 (FSTL1) has been proposed as an...
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Long non-coding RNA LOXL1-AS1: a potential biomarker and therapeutic target in human malignant tumors
Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 nucleotides. Despite their inability to code proteins, multiple studies...
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Identification of a potential bioinformatics-based biomarker in keloids and its correlation with immune infiltration
Keloid formation is a pathological consequence resulting from cutaneous irritation and injury, primarily attributed to excessive collagen matrix...
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Potential biomarker signatures in male infertility: integrative genomic analysis
BackgroundStudies have attributed 50% of infertility cases to male infertility, 15% of which is caused by idiopathic genetic factors. Currently, no...
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Plasma alpha B crystallin as potential biomarker for predicting pre-operative seizures in glioma
PurposeGlioma-associated epilepsy affects a significant proportion of glioma patients, contributing to disease progression and diminished survival...
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The Biomarker Toolkit — an evidence-based guideline to predict cancer biomarker success and guide development
BackgroundAn increased number of resources are allocated on cancer biomarker discovery, but very few of these biomarkers are clinically adopted. To...
