Search
Search Results
-
Expanding the positivity offset theory of anhedonia to the psychosis continuum
People with schizophrenia and negative symptoms show diminished net positive emotion in low-arousing contexts (diminished positivity offset) and...
-
RSV testing practice and positivity by patient demographics in the United States: integrated analyses of MarketScan and NREVSS databases
BackgroundRSV-incidence estimates obtained from routinely-collected healthcare data (e.g., MarketScan) are commonly adjusted for under-reporting...
-
SARS-CoV-2, influenza A/B and respiratory syncytial virus positivity and association with influenza-like illness and self-reported symptoms, over the 2022/23 winter season in the UK: a longitudinal surveillance cohort
BackgroundSyndromic surveillance often relies on patients presenting to healthcare. Community cohorts, although more challenging to recruit, could...
-
Role of diffusion-weighted MRI for prediction of regional lymph node positivity in radiologically organ-confined renal tumour: a prospective study
BackgroundLymph node metastasis is one of the major factors that decide the prognosis of renal cell carcinoma. Presently, lymphadenectomy is only...
-
Human norovirus (HuNoV) GII RNA in wastewater solids at 145 United States wastewater treatment plants: comparison to positivity rates of clinical specimens and modeled estimates of HuNoV GII shedders
BackgroundHuman norovirus (HuNoV) is a leading cause of disease globally, yet actual incidence is unknown. HuNoV infections are not reportable in the...
-
Assessing secular trends in HIV rapid diagnostic test uptake and positivity in Northeast Iran, a country in MENA region; ingredients for target-specific prevention policies
BackgroundIran is amongst the first three countries in Middle East and North Africa (MENA) region where two-thirds of region’s new HIV infections are...
-
Short time to positivity of blood culture predicts mortality and septic shock in bacteremic patients: a systematic review and meta-analysis
BackgroundThe value of time to positivity (TTP) on diagnosis for catheter-related bloodstream infection and distinguishment on bacteria group and...
-
Time-to-positivity of Mycobacterium avium complex in broth culture associates with culture conversion
BackgroundMycobacterial time to positivity (TTP) in liquid culture media has predictive value for longer term outcomes in pulmonary tuberculosis, but...
-
Threshold for defining PSMA-positivity prior to 177Lu-PSMA therapy: a comparison of [68Ga]Ga-PSMA-11 and [18F]F-DCFPyL in metastatic prostate cancer
BackgroundIn 2022, the American Food and Drug Administration and the European Medicines Agency approved [ 177 Lu]Lu-PSMA-617 (PLUVICTO™, Novartis AG,...
-
Role of microsatellite instability and HER2 positivity in locally advanced esophago-gastric cancer patients treated with peri-operative chemotherapy
PurposeNeoadjuvant chemotherapy (NAC) significantly improved the prognosis of patients with locally advanced gastric cancer (LAGC). Several...
-
The association between subclinical hypothyroidism and TPOAb positivity with infertility in a population-based study: Tehran thyroid study (TTS)
BackgroundThyroid autoimmunity(TAI) is the most prevalent autoimmune condition in women of fertile age. There are increasing data regarding the...
-
Deep learning-based amyloid PET positivity classification model in the Alzheimer’s disease continuum by using 2-[18F]FDG PET
BackgroundConsidering the limited accessibility of amyloid position emission tomography (PET) in patients with dementia, we proposed a deep learning...
-
Intensity of immune/clotting assays relate to multiple antiphospholipid antibody positivity in thrombotic primary antiphospholipid syndrome
The dual positivity (DP) and triple positivity (TP) concepts bypass the poor comparability of immune/clotting assay for the laboratory classification...
-
Longitudinal pathways of cerebrospinal fluid and positron emission tomography biomarkers of amyloid-β positivity
Mismatch between CSF and PET amyloid-β biomarkers occurs in up to ≈20% of preclinical/prodromal Alzheimer’s disease individuals. Factors underlying...
-
Proton-pump inhibitors are associated with a high false-positivity rate in faecal immunochemical testing
BackgroundFalse-positivity rates in faecal immunochemical test (FIT) can be affected by drug exposure. We aimed to assess the association between...
-
Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis
BackgroundNatalizumab and fingolimod are used as high-efficacy treatments in relapsing–remitting multiple sclerosis. Several observational studies...
-
Model correction of diagnostic coding-based RSV incidence for children 0–4 years in the US
BackgroundAlthough administrative claims data have a high degree of completeness, not all medically attended Respiratory Syncytial Virus-associated...
-
Hepatitis C viraemic and seroprevalence and risk factors for positivity in Northwest Cambodia: a household cross-sectional serosurvey
BackgroundDespite a dramatic reduction in HCV drug costs and simplified models of care, many countries lack important information on prevalence and...
-
Trends in non-focal neurological chief complaints and CT angiography utilization among adults in the emergency department
Prudent imaging use is essential for cost reduction and efficient patient triage. Recent efforts have focused on head and neck CTA in patients with...
-
Does cavity margin shaving reduce residual tumor and re‐excision rates? A systematic review
PurposeCavity shaving (CS) is a surgical technique used in the treatment of breast cancer (BC). It may reduce margin positivity in histologic...