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Pineal/germ cell tumors and pineal parenchymal tumors
IntroductionPineal region tumors (PRTs) are tumors arising from the pineal gland and the paraspinal structures. These tumors are rare and...
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A case of a pineal parenchymal tumor of intermediate differentiation with bifocal lesions differentiated by negative placental alkaline phosphatase in the spinal fluid
Placental alkaline phosphatase (PLAP) in the spinal fluid is helpful for the diagnosis of intracranial germinomas. Bifocal lesions involving the...
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Time to dismiss boost? Outcomes of children with localized and metastatic germinoma
PurposeTo determine long-term outcomes of a cohort of children with germinoma treated with chemotherapy and radiation therapy without primary tumor...
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Diffuse peritoneal dissemination of intracranial pure germinoma via ventriculoperitoneal shunt
Germinomas frequently cause hydrocephalus, and ventriculoperitoneal shunts (VPS) have been commonly used for their management. Although VPS can...
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Treatment outcomes for response-based radiotherapy in children and adolescents with central nervous system germinoma: a prospective study
PurposeThe optimal dose and range of radiotherapy for central nervous system (CNS) germinoma have not yet been established. This study aimed to...
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Prognostic factors of pediatric pineal region tumors at a single institution
PurposeThis study aimed to identify factors of a worse prognosis among different histological types of pineal region tumors in pediatric patients...
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Second-look surgery for pineal region tumors
PurposeSurgical resection of pineal region tumors is challenging because of close proximity to the vein of Galen draining system and the...
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Pediatric pineal region masses: a single-center experience over 25 years
PurposePineal region tumors (PRT) represent less than 1% of brain neoplasms. The rare and heterogeneous nature of these tumors is reflected in the...
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Intracranial germinoma in the lateral ventricle with polydipsia and polyuria: a case report and literature review
Central nervous system germ cell tumors (CNSGCTs) are rare neoplasms which usually develop in the midline structures. They are occasionally involved...
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Influence of growth hormone therapy on germinoma survivors
PurposeDue to the effectiveness of growth hormone therapy (GHT), the number of cancer survivors receiving GHT has increased. Previous studies had...
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The surgical intervention for pineal region tumors
Histological and molecular characterization is essential for the diagnosis of pediatric brain tumors. In the pineal region tumors, it is necessary to...
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Occult extracranial malignancy after complete remission of pineal mixed germ cell tumors: a rare case report and literature review
BackgroundExtracranial metastasis can occur in intracranial germ cell tumors (GCTs), but it is very rare. Recurrence or metastasis of...
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Simultaneous biportal endoscopic management of pineal region tumors in patients with obstructive hydrocephalus: technical notes
BackgroundThe goal of this study is to show the feasibility and benefits of using the simultaneous biportal endoscopic procedure to treat pineal...
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An atypical location of pineoblastoma RB1 subgroup without pineal or retinal tumor
PurposeTo describe the clinical and imaging features of a sellar-suprasellar pineoblastoma RB1 subgroup without pineal or retinal involvement.
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Optic nerve sheath diameter correlates with both success and failure of hydrocephalus treatment in pediatric patients with pineal region lesions
BackgroundPineal region lesions in children are heterogenous pathologies often symptomatic due to occlusive hydrocephalus and thus elevated...
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Temporal profile of serum melatonin levels in paediatric pineal tumours subjected to surgery: newer insights
IntroductionPineal tumours (PTs) are rare and histologically variable. Serum melatonin is a well-known product of this gland, albeit with uncertain...
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Sellar germinoma mimicking IgG4-related hypophysitis: a case report
BackgroundThe differential diagnosis of IgG4-related hypophysitis and other inflammatory diseases or tumors involving sellar region is challenging...
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Neuroendoscopic transventricular transchoroidal approach for access to the posterior zone of the third ventricle or pineal region
The endoscopic transventricular transchoroidal approach facilitates entry into the posterior part of the third ventricle, allowing a visualization...
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Pediatric pineal region tumors: institutional experience of surgical managements with posterior interhemispheric transtentorial approach
PurposeResecting pineal region tumors in children is often challenging. Several approaches have been proposed and practiced. A personal series of...
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Neuroendoscopy in the management of pineal region tumours in children
IntroductionPineal region tumours (PRTs) are more common in children and represent a wide variety of lesions. The practise of a radiation test dose...
