Search
Search Results
-
Targeting the pancreatic tumor microenvironment by plant-derived products and their nanoformulations
Pancreatic cancer remains a significant health issue with limited treatment options. The tumor stroma, a complex environment made up of different...
-
Pancreatic Cancer Current Therapeutics and Future Directions
Pancreatic cancer is a challenging and complex disease characterized by a dense fibrotic stroma and an immunosuppressive tumor...
-
CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival
Pancreatic cancer is an aggressive disease with a 5 year survival rate of 13%. This poor survival is attributed, in part, to limited and ineffective...
-
A case report of a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue lymphoma
BackgroundCollision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant...
-
A case of chronic expanding hematoma mimicking a cystic pancreatic tumor
BackgroundA chronic expanding hematoma is an uncommon entity described as an organized blood collection that increases in size after the initial...
-
ENO1 promotes immunosuppression and tumor growth in pancreatic cancer
BackgroundPancreatic adenocarcinoma (PAAD) is a highly aggressive and malignant cancer type with the highest mortality rate of all major cancers....
-
Personalized tumor vaccine for pancreatic cancer
BackgroundPancreatic cancer is a highly lethal malignancy often presenting with advanced disease and characterized by resistance to standard...
-
DDX18 drives tumor immune escape through transcription-activated STAT1 expression in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) resists to current treatments due to its inherent tumor heterogeneity, therapy-resistant cancer...
-
The importance of CXCR4 expression in tumor stroma as a potential biomarker in pancreatic cancer
BackgroundPancreatic ductal adenocarcinoma (PDAC) is one of the main causes of cancer mortality in the world. A characteristic feature of this cancer...
-
Tumor-derived interleukin 35 mediates the dissemination of gemcitabine resistance in pancreatic adenocarcinoma
Rapid development of drug resistance after chemotherapy is a major cause of treatment failure in individuals with pancreatic ductal adenocarcinoma...
-
Using a CA19-9 Tumor Marker Gene Test to Assess Outcome After Pancreatic Cancer Surgery
BackgroundCancer antigen 19-9 (CA19-9) is widely used as a marker of pancreatic cancer tumor burden and response to therapy. Synthesis of CA19-9 and...
-
Spatial immune composition of tumor microenvironment in patients with pancreatic cancer
This study examined the composition of the immune microenvironment at different sites within resected pancreas specimens from patients with...
-
The role of innate immune cells as modulators of the tumor microenvironment in the metastasis and treatment of pancreatic cancer
Pancreatic cancer is a highly aggressive disease, which is often diagnosed late. Consequently, metastasis is common among newly diagnosed patients,...
-
Detection of HHV-6 Virus in specimen of a ductal pancreatic adenocarcinoma with comparison in tumor and normal tissue
AimsThe association of human herpesvirus 6 (HHV-6) species with pancreatic cancer is controversially discussed. The aim of this study was to further...
-
The radiomorphological appearance of the invasive margin in pancreatic cancer is associated with tumor budding
PurposePancreatic cancer (PDAC) is characterized by infiltrative, spiculated tumor growth into the surrounding non-neoplastic tissue. Clinically, its...
-
Pancreatic metastasis of malignant melanoma presenting as a tumor occluding the main pancreatic duct
Metastasis to the pancreas is rare, especially for malignant melanoma. In these scarce cases, tumors normally present in the parenchyma of the...
-
Review of Merkel cell carcinoma with solitary pancreatic metastases mimicking primary neuroendocrine tumor of the pancreas
Objective/BackgroundMerkel cell carcinoma (MCC) but metastases to the pancreas are very rare. There are only a few cases of isolated metastases of...
-
A duodenal gastrointestinal stromal tumor mimicking a pancreatic neuroendocrine tumor: a case report
BackgroundDuodenal gastrointestinal stromal tumors are rare. If tumor growth is extraluminal and involves the head of the pancreas, the diagnosis of...
-
Severe hypercalcemia due to metastatic pancreatic neuroendocrine tumor: a case report
BackgroundHypercalcemia of malignancy, as a paraneoplastic syndrome, is the most common metabolic disorder that accounts for 30% of malignancies and...
-
Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma
BackgroundRecent evidence suggests that the presence of microbiome within human pancreatic ductal adenocarcinoma (PDAC) tissue potentially influences...
