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Pancreatic Endocrine Insufficiency
Purpose of the ReviewThis review aims to consolidate the latest knowledge on type 3c diabetes mellitus (T3cDM) and its management and pancreatic...
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Exocrine Pancreatic Insufficiency Dosing Guidelines for Pancreatic Enzyme Replacement Therapy Vary Widely Across Disease Types
BackgroundPancreatic enzyme replacement therapy (PERT) is the standard treatment for exocrine pancreatic insufficiency (EPI). However, many...
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Exocrine pancreatic insufficiency following bariatric surgery: unveiling alternative aetiology—case report and short review
Bariatric surgery (BS) is currently the most effective treatment for severe obesity, requiring ongoing multidisciplinary follow-up to ensure proper...
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Symptoms, burden, and unmet needs of patients living with exocrine pancreatic insufficiency: a narrative review of the patient experience
Exocrine pancreatic insufficiency (EPI) stems from a deficiency of functional pancreatic enzymes with consequent maldigestion and malnutrition. EPI...
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Pancreatic enzyme replacement therapy in subjects with exocrine pancreatic insufficiency and diabetes mellitus: a real-life, case–control study
BackgroundExocrine pancreatic insufficiency (EPI) can be associated with all types of diabetes. Pancreatic enzyme replacement therapy (PERT) has...
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Exocrine Pancreatic Insufficiency Is Common in Celiac Disease: A Systematic Review and Meta-Analysis
The prevalence of celiac disease (CD) is approximately 1% in the US. Studies have shown possible association between exocrine pancreatic...
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Exocrine pancreatic insufficiency after bariatric surgery: a bariatric surgery center of excellence experience
IntroductionGastrointestinal symptoms such as diarrhea, bloating, abdominal pain, and nausea are common after bariatric surgery (BS) and can lead to...
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Screening for undiagnosed pancreatic exocrine insufficiency (PEI) in a cohort of diabetic patients using faecal elastase testing and PEI scoring system
IntroductionType 1 and type 2 diabetes mellitus (DM) are often accompanied by mild forms of pancreatic exocrine insufficiency (PEI). The prevalence...
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Prevalence and Risk Factors for Pancreatic Insufficiency After Partial Pancreatectomy
BackgroundThis study aimed to determine the rate, timing, and predictors of diabetes and exocrine pancreatic insufficiency after pancreatectomy in...
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The pancreatic exocrine function in patients with pancreatic endocrine insufficiency: the evaluation with cine-dynamic magnetic resonance cholangiopancreatography using a spatially selective inversion-recovery pulse and T1 map**
PurposeTo evaluate the association of the pancreatic exocrine function estimated by cine-dynamic magnetic resonance cholangiopancreatography (MRCP)...
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Exocrine Pancreatic Insufficiency is Undiagnosed in Some Patients with Diarrhea-Predominant Irritable Bowel Syndrome Using the Rome IV Criteria
Background and AimsIrritable bowel syndrome (IBS) is one of the most frequent disorders in clinical practice, with a mean 7.6–10.8% worldwide...
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Pancreas Transplant for Combined Pancreatic Endocrine and Exocrine Insufficiency
Purpose of ReviewTo highlight the role of pancreas transplantation in pancreatogenic diabetes and to familiarize the reader with disease processes...
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Pancreatic Dysfunction and Reduction in Quality of Life Is Common After Pancreaticoduodenectomy
BackgroundImprovements in survival after pancreaticoduodenectomy has increased the number of patients potentially at risk of pancreatic...
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Open Pancreatic Duct Stenting in Pancreatic Trauma: A Bridge in the Path of Pancreatic Preservation
Pancreatic trauma is often associated with high mortality and morbidity. Current management protocol advises conservative management when the duct is...
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Exocrine Pancreatic Insufficiency Following Gastric Resectional Surgery—is Routine Pancreatic Enzyme Replacement Therapy Necessary?
The data on exocrine pancreatic insufficiency (EPI) following gastric resectional surgery is variable, ranging from 26% to as high as 100%. This...
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Impact of pancreatic ductal occlusion on postoperative outcomes in pancreatic head cancer patients undergoing neoadjuvant therapy
BackgroundPancreatic ductal occlusion can accompany pancreatic head cancer, leading to pancreatic exocrine insufficiency (PEI) and adverse effects on...
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Gastrectomy reduces pancreatic secretory function via pancreatic atrophy
PurposeAlthough reports suggest that the pancreatic volume decreases after gastrectomy for gastric cancer, the relationship between the pancreatic...
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Central versus distal pancreatectomy for low-grade and benign pancreatic neck-body tumours
PurposeCentral pancreatectomy (CP) offers parenchymal preservation compared to conventional distal pancreato-splenectomy for pancreatic neck and body...
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Organ preserving pancreatic resections offer better long-term conservation of pancreatic function at the expense of high perioperative major morbidity: a fair trade-off for benign or low malignant potential pancreatic neoplasms—a single-center experience
BackgroundStandard pancreatic resections (SPRs) might have long-term deleterious effects on pancreatic function, without added oncological advantage...