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Osteopenia of prematurity and associated nutritional factors: case–control study
BackgroundPreterm newborn nutrition affects postnatal skeletal growth and bone mineralization, but studies have not yet fully concluded the...
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Relationship of caffeine regimen with osteopenia of prematurity in preterm neonates: a cohort retrospective study
BackgroundCaffeine is a routinely prescribed pharmacological active compound in neonatal intensive care units (NICU) for treating apnea of...
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Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study
BackgroundEarly administration of intravenous (IV) caffeine (initiation within 2 days of life) is an effective treatment strategy for the management...
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Role of fibroblast growth factor-23 as an early marker of metabolic bone disease of prematurity
PurposeMetabolic bone disease of prematurity (MBDP) remains a significant cause of morbidity in extremely premature newborns. In high-risk patients,...
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Early elevated alkaline phosphatase as a surrogate biomarker of ongoing metabolic bone disease of prematurity
Very low birth weight (VLBW) neonates present a high risk of metabolic bone disease (MBD). Our main objective was to determine the easiest way to...
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Scleral buckling surgery for stage 4A and 4B retinopathy of prematurity in critically ill neonates
PurposeTo determine the efficacy of scleral buckling in eyes with stage 4A and 4B retinopathy of prematurity (ROP).
MethodsSeven eyes of five...
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Effect of physical therapy on bone remodelling in preterm infants: a multicenter randomized controlled clinical trial
BackgroundPreterm infants have a low level of bone mineralization compared to those born at term, since 80% of calcium incorporation occurs at the...
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Risk Calculator for Bronchopulmonary Dysplasia in Preterm Neonates: A Prospective Observational Study
ObjectivesTo determine the incidence, risk factors, and accuracy of a previously published risk estimator in predicting Bronchopulmonary dysplasia...
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Continuous versus intermittent bolus infusion of calcium in preterm infants receiving total parenteral nutrition: a randomized blind clinical trial
BackgroundPremature neonates need adequate nutritional support to provide sufficient essential nutrients for optimal growth. Calcium (Ca) is one of...
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Profile of metabolic bone disease in extremely low birth weight (ELBW) and very low birth weight (VLBW) neonates
BackgroundMetabolic bone disease (MBD) is an important cause of morbidity in premature, very low birth weight (VLBW), and sick infants and, if left...
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Comparative Growth Outcomes in Very Low Birth Weight Infants: Evaluating Different Feeding Strategies
ObjectivesTo assess the growth pattern of preterm, very low birth weight (VLBW) appropriate for gestational age (AGA) infants on three different...
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Neonatal upper limb fractures – a narrative overview of the literature
The aim of this paper is to review the topic of neonatal fractures of the upper limb, describing the different types of fractures focusing on the...
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Caffeine is a risk factor for osteopenia of prematurity in preterm infants: a cohort study
BackgroundCaffeine, the most commonly used medication in Neonatal Intensive Care Units, has calciuric and osteoclastogenic effects.
Methods ...
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Metabolic Bone Disease in Preterm Neonates With Fetal Growth Restriction (FGR): A Prospective Cohort Study
ObjectivesTo study the association of fetal growth restriction (FGR) with metabolic bone disease in preterm neonates.
MethodologyThis prospective...
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Evaluation of radiologic evidence of metabolic bone disease in very low birth weight infants at fourth week of life
AimThe aim of this study is to determine the incidence of metabolic bone disease (MBD) and assess the risk factors for development radiologic...
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Predictors for poor daily weight gain in preterm neonates exposed to different dose regimens of caffeine in ICU- a retrospective cohort study
BackgroundWith a wide therapeutic index, efficacy, ease of use, and other neuroprotective and respiratory benefits, caffeine citrate(CC) is currently...
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Incidence of venous thromboembolic events not related to vascular catheters in a prospective cohort of critically ill children
The risk for venous thromboembolism (VTE) is considered to be low in the general paediatric intensive care unit (PICU) population, and...
