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On the occasion of the centennial of insulin therapy (1922–2022), II-Organotherapy of diabetes mellitus (1906–1923): Acomatol. Pancreina. Insulin.
AimsThe general objective has been the historiographical investigation of the organotherapy of diabetes mellitus between 1906 and 1923 in its...
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I-European research, the cradle of the discovery of the antidiabetic hormone: the pioneer roles and the relevance of Oskar Minkowski and Eugène Gley
AimsThe introduction of hormonal treatment in severe diabetes in 1922 represented a clinical and social impact similar to that of antibiotic therapy....
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The medicalization of testosterone: reinventing the elixir of life
The pursuit of longevity, which during the Renaissance era was limited to longing for miraculous ways of rejuvenation, such as bathing in the...
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Testosteron door de eeuwen
The search for the male hormone begins with the experiments of the German physiologist Bertholdt in 1849 who transplanted a rooster’s testes into...
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The Nobel Prize of Physiology or Medicine, 1923: controversies on the discovery of the antidiabetic hormone
AimsTo analyze the main contributions to the discovery of the antidiabetic hormone in the period between
1889 , the year in which Oskar Minkowski...
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Operational definition of complementary, alternative, and integrative medicine derived from a systematic search
BackgroundIdentifying what therapies constitute complementary, alternative, and/or integrative medicine (CAIM) is complex for a multitude of reasons....
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Brazilian red propolis: phytochemical screening, antioxidant activity and effect against cancer cells
BackgroundThe implementation of new public healthcare models that stimulate the use of natural products from traditional medicine, as a so-called...
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Elie Metchnikoff—The founder of longevity science and a founder of modern medicine: In honor of the 170th anniversary
The years 2015–2016 mark a double anniversary—the 170th anniversary of birth and the 100th anniversary of death—of one of the greatest Russian...
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Pituitary-gonadal axis: historical notes
Though it was appreciated at a very early time that removal of gonads had evident consequences, the anatomy and function of the gonads were...
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Current issues with β2-adrenoceptor agonists
The discovery that dessicated adrenal glands had beneficial effects in asthma arose in 1900 following a vogue for studying organotherapy at the end...
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Diabetes Insipidus: Historical Aspects
The contributions to our present knowledge and understanding of diabetes insipidus are briefly surveyed. Though a disease presenting with polyuria...
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G. Frank Lydston (1858–1923) revisited: androgen therapy by testicular implantation in the early twentieth century
At the beginning of the twentieth century the transplantation or implantation of either human or animal testicular tissue was an appealing form of...
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Androgens and prostate cancer
Over 60 years ago Huggins and Hodges demonstrated the importance of androgens and prostate cancer. Since then, significant research has revealed that...
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Surgery of chronic pancreatitis: Chronicle of confusion and despair
The evolution of surgery for pancreatitic disease has been arduous owing to the technical difficulties of addressing the organ and the lack of...
