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Assessing circulating tumour DNA (ctDNA) as a prognostic biomarker in locally advanced rectal cancer: a systematic review and meta-analysis
IntroductionCirculating tumour DNA (ctDNA) has emerged as a promising biomarker in various cancer types, including locally advanced rectal cancer...
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Inter-rater reliability of risk of bias tools for non-randomized studies
PurposeThere is limited knowledge on the reliability of risk of bias (ROB) tools for assessing internal validity in systematic reviews of exposure...
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Utility of thiol/disulphide homeostasis as a biomarker for acute appendicitis: a systematic review and meta-analysis
The aim of this study was to analyze the role of thiol/disulfide homeostasis (TDH) parameters as an indicator of oxidative stress in acute...
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The effect of animal-assisted interventions on the course of neurological diseases: a systematic review
BackgroundIn our experience, working with a therapy animal strengthens endurance, maintains motivation, provides a sense of achievement, and boosts...
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Comparison between umbilical and right upper transverse abdominal incisions for pyloromyotomy: a systematic review and meta-analysis
The aim of this study was to compare the operative parameters and complication rates between the umbilical (UMB) and right upper quadrant (RUQ) skin...
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Comparing One-Stage Versus Two-Stage Ridge Splitting Procedures: A Systematic Review and Meta-Analysis
AimTo determine, summarize, assess and compare one-stage with two-stage ridge split procedures by systematically reviewing the existing scientific...
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Gamma knife radio surgery for cerebral arteriovenous malformation (AVM) in children: a systematic review and meta-analysis of clinical outcomes
This article aims to evaluate the safety and effectiveness of Gamma Knife radiosurgery as a treatment modality for pediatric cerebral arteriovenous...
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Clinical Significance of Sarcopenia in Elderly Patients Undergoing Endoscopic Submucosal Dissection: A Systematic Review and Meta-analysis
Background and AimsAs global life expectancy rises and gastrointestinal tumor incidence increases, more elderly patients are undergoing endoscopic...
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Enhancing study quality assessment: an in-depth review of risk of bias tools for meta-analysis—a comprehensive guide for anesthesiologists
BackgroundYearly, a multitude of randomized controlled trials are published, overwhelming clinicians with conflicting information; this data...
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Impact of interventions on the quality of life of cancer patients: a systematic review and meta-analysis of longitudinal research
The impact of cancer interventions has been conducted in several research due to the significant burden of this non-communicable disease. The...
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Relationship between human papillomavirus and serum vitamin D levels: a systematic review
BackgroundHuman papillomavirus (HPV) is one of the most prevalent sexually transmitted diseases worldwide. The present review was conducted to...
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Continuous data capture of gait and mobility metrics using wearable devices for postoperative monitoring in common elective orthopaedic procedures of the hip, knee, and spine: a sco** review
BackgroundSurgical procedures involving the hip, knee, or spine represent a majority of orthopaedic procedures performed electively in the health...
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Meta-analysis of differences in neutrophil to lymphocyte ratio between hypertensive and non-hypertensive individuals
This study systematically reviewed the evidence regarding differences in the neutrophil to lymphocyte ratio (NLR) level between hypertensive and...
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Diagnosis and treatment of appendicitis: systematic review and meta-analysis
BackgroundThe optimal diagnosis and treatment of appendicitis remains controversial. This systematic review details the evidence and current best...
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Risk of teratogenicity in continued pregnancy after gestational exposure to mifepristone and/or misoprostol: a systematic review and meta-analysis
PurposeThis meta-analysis aimed to comprehensively assess the teratogenic risk to offspring associated with continuing pregnancy after administering...
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High prevalence of erectile dysfunction in men with hyperthyroidism: a meta-analysis
ObjectiveThe objective of this study was to evaluate the association between hyperthyroidism and the risk of develo** erectile dysfunction (ED).
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Getting old in the desired gender: a systematic review on aging diseases in transgender people
IntroductionThe growing demographic presence of the transgender (TGD) population has sparked an increase in clinical investigations focusing on the...
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The correlation between osteoporotic vertebrae fracture risk and bone mineral density measured by quantitative computed tomography and dual energy X-ray absorptiometry: a systematic review and meta-analysis
SummaryThis paper presents a comparison of quantitative computed tomography (QCT) and dual-energy X-ray absorptiometry (DXA) in osteoporosis with...
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Robot-assisted surgery versus laparoscopic surgery of ureteropelvic junction obstruction in children: a systematic review and meta-analysis
The clinical effectiveness and safety of robot-assisted laparoscopic pyeloplasty (RP) compared with laparoscopic pyeloplasty (LP) have not been...
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Quantitative physical performance tests can effectively detect Degenerative Cervical Myelopathy: A systematic review and meta-analysis
PurposeThis review aimed to identify effective physical performance tests (PPT) as clinical outcome indicators for detecting and monitoring...
