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Trends in the use of neuromuscular blocking agents, reversal agents and neuromuscular transmission monitoring: a single-centre retrospective cohort study
BackgroundResidual neuromuscular blockade (rNMB) remains a persistent and preventable problem, with serious risks.
MethodsOur objective was to...
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Physiology of Neuromuscular Transmission and Applied Pharmacology of Muscle Relaxants
Purpose of ReviewThe purpose of this clinical review is to summarize the physiology of the neuromuscular junction (NMJ) in the normal and denervated...
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Monitoring the Depth of Neuromuscular Blockade
Purpose of ReviewIn 2023, the American Society of Anesthesiologists published its first practice guideline document regarding the monitoring and...
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Monitoring Depth of Neuromuscular Blockade and Adequacy of Reversal: Clinical and Pharmacoeconomic Implications
Purpose of ReviewThis review summarizes current evidence on best practice management of neuromuscular blocking agents (NMBAs). Furthermore, the...
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Patterns of Stimulation, Site of Monitoring, and Accuracy in Detecting Residual Neuromuscular Blockade
Purpose of ReviewNeuromuscular blocking agents (NMBAs) are important for general anesthesia because they induce temporary paralysis of skeletal...
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Neuromuscular junction involvement in inherited motor neuropathies: genetic heterogeneity and effect of oral salbutamol treatment
ObjectivesInherited defects of the neuromuscular junction (NMJ) comprise an increasingly diverse range of diseases. Several recently identified genes...
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Frequency and satisfaction of conventional and complementary or alternative therapies for neuromuscular disorders
BackgroundCausal therapies are not yet available for most neuromuscular diseases. Additionally, data on the use of complementary or alternative...
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EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders
BackgroundThe EURO-NMD Registry collects data from all neuromuscular patients seen at EURO-NMD's expert centres. In-kind contributions from three...
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Update on Paraneoplastic Neuromuscular Disorders
Purpose of ReviewTo review the clinical presentation and diagnosis of different paraneoplastic neuromuscular disorders and the available data on...
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Comparative performance of stimpod electromyography with mechanomyography for quantitative neuromuscular blockade monitoring
PurposeThe purpose of this study was to compare the Stimpod electromyograph neuromuscular blockade monitor to mechanomyography, which is widely...
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Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Background:Neuromuscular blocking agents are frequently administered to pigs used for research. In humans, administration of the drugs is not without...
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Core strength, dynamic balance and performance enhancement in female athletes with ligament dominance in response to sports-specific SportsMetrics neuromuscular training programs
PurposeThis study investigated the effects of SportsMetrics neuromuscular training programs on core strength, balance and performance of female...
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Optimizing Reversal of Neuromuscular Block in Older Adults: Sugammadex or Neostigmine
Residual neuromuscular paralysis, the presence of clinically significant weakness after administration of pharmacologic neuromuscular blockade...
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Improved analysis method of neuromuscular junction in Drosophila larvae by transmission electron microscopy
The Drosophila neuromuscular junction is an excellent model for neuroscience research. However, the distribution of neuromuscular junctions is very...
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Lipid metabolism and neuromuscular junction as common pathways underlying the genetic basis of erectile dysfunction and obstructive sleep apnea
Erectile dysfunction (ED) incidence is higher in patients with obstructive sleep apnea (OSA). Studies have suggested that ED and OSA may activate...
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A systematic review of telemedicine for neuromuscular diseases: components and determinants of practice
IntroductionNeuromuscular diseases (NMDs) entail a group of mostly inherited genetic disorders with heterogeneous phenotypes impacting muscles, the...
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Low frequency neuromuscular electrical stimulation applied to the bulbospongiosus muscle prolongs the ejaculation latency in a rat model
Premature ejaculation (PE) is common, but its true pathophysiology is not clear, and treatments are limited. We aimed to investigate the effect of...
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Mechanisms of neuromodulatory volume transmission
A wealth of neuromodulatory transmitters regulate synaptic circuits in the brain. Their mode of signaling, often called volume transmission, differs...
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Effect of neuromuscular reversal with neostigmine/glycopyrrolate versus sugammadex on postoperative ileus following colorectal surgery
BackgroundPostoperative ileus (POI) is a common complication following colorectal surgery and is mediated in part by the cholinergic...
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Deep Neuromuscular Block Attenuates Chronic Postsurgical Pain and Enhances Long-Term Postoperative Recovery After Spinal Surgery: A Randomized Controlled Trial
IntroductionThe effects of deep neuromuscular block (DNMB) on chronic postsurgical pain (CPSP) have not been conclusively determined. Moreover, a...
