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Ferrostatin-1 facilitated neurological functional rehabilitation of spinal cord injury mice by inhibiting ferroptosis
BackgroundTo seek the potential therapy for spinal cord injury, Ferrostatin-1, the first ferroptosis inhibitor, was administrated in spinal cord...
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RETRACTED ARTICLE: Prediction of patient’s neurological recovery from cervical spinal cord injury through XGBoost learning approach
Due to the diversity of patient characteristics, therapeutic approaches, and radiological findings, it can be challenging to predict outcomes based...
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Correlation between early computed tomography findings and neurological outcome in pediatric traumatic brain injury patients
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children. Head computed tomography (CT) is frequently utilized for...
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S100B predicts neurological injury and 30-day mortality following surgery for acute type A aortic dissection: an observational cohort study
BackgroundNeurological injuries are frequent following Acute Type A Aortic Dissection (ATAAD) repair occurring in 4–30% of all patients. Our...
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Association Between Admission Ionized Calcium Level and Neurological Outcome of Patients with Isolated Severe Traumatic Brain Injury: A Retrospective Cohort Study
BackgroundTraumatic brain injury (TBI) is a leading cause of death and disability worldwide. Pathophysiological processes following initial insult...
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Unfavorable Neurological Outcomes with Incremental Cardiopulmonary Resuscitation Duration in Cardiac Arrest Brain Injury: A Systematic Review and Meta-Analysis
The duration of cardiopulmonary resuscitation (CPR) affects neurological outcomes. Conclusive data on its decremental effect on neurological outcomes...
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A dynamic nomogram for predicting the probability of irreversible neurological dysfunction after cervical spinal cord injury: research based on clinical features and MRI data
BackgroundIrreversible neurological dysfunction (IND) is an adverse event after cervical spinal cord injury (CSCI). However, there is still a...
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The Role of Riluzole in Acute Traumatic Cervical Spinal Cord Injury with Incomplete Neurological Deficit: A Prospective, Randomised Controlled Study
IntroductionRiluzole, a benzothiazole sodium channel blocker is acknowledged as a neuroprotective agent in spinal cord injury (SCI). Most of this...
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Traumatic Brain Injury
In spite of great improvements in prehospital, critical care, and surgical management, traumatic brain injury is still a leading cause of death and...
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Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage—study protocol for a randomized clinical trial
BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a neurological emergency, affecting a younger population than individuals experiencing an...
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Evaluation of canine adipose-derived mesenchymal stem cells for neurological functional recovery in a rat model of traumatic brain injury
BackgroundTraumatic brain injury (TBI) is a common condition in veterinary medicine that is difficult to manage.Veterinary regenerative therapy based...
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Early systemic insults following traumatic brain injury: association with biomarker profiles, therapy for intracranial hypertension, and neurological outcomes—an analysis of CENTER-TBI data
PurposeWe analysed the impact of early systemic insults (hypoxemia and hypotension, SIs) on brain injury biomarker profiles, acute care requirements...
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Inflammasomes in neurological disorders — mechanisms and therapeutic potential
Inflammasomes are molecular scaffolds that are activated by damage-associated and pathogen-associated molecular patterns and form a key element of...
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Neurological involvement in hematopoietic stem cell transplantation-associated thrombotic microangiopathy
Transplantation-associated thrombotic microangiopathy (TA-TMA) is a well-recognized serious complication of hematopoietic stem cell transplantation...
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Neurofilaments as biomarkers in neurological disorders — towards clinical application
Neurofilament proteins have been validated as specific body fluid biomarkers of neuro-axonal injury. The advent of highly sensitive analytical...
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Does cervical curvature affect neurological outcome after incomplete spinal cord injury without radiographic abnormality (SCIWORA): 1-year follow-up
BackgroundAt present, surgery is the primary clinical treatment for SCIWORA patients, but conservative treatment still plays an important role in...
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Neurological and respiratory effects of lung protective ventilation in acute brain injury patients without lung injury: brain vent, a single centre randomized interventional study
IntroductionLung protective ventilation (LPV) comprising low tidal volume (VT) and high positive end-expiratory pressure (PEEP) may compromise...
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The Role of Rehabilitation in Neurological Critical Care: Innovations in Early Mobilization
Purpose of reviewThis review appraises the existing literature to highlight the benefits, barriers, and role of rehabilitation in the early...
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The impact of time from injury to surgery on the risk of neuropathic pain after traumatic spinal cord injury
Traumatic spinal cord injury (SCI) is a devastating neurological disorder often accompanied by neuropathic pain (NeP), significantly affecting...
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Cerebral Autoregulation: A Target for Improving Neurological Outcomes in Extracorporeal Life Support
Despite improvements in survival after illnesses requiring extracorporeal life support, cerebral injury continues to hinder successful outcomes....