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Longitudinal NGAL and cystatin C plasma profiles present a high level of heterogeneity in a mixed ICU population
BackgroundNGAL and Cystatin C (CysC) as biomarkers for the early detection of AKI are subject to both pathophysiological, as well as patient related...
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Preoperative and postoperative urinary NGAL levels in children with bladder exstrophy
BackgroundUrinary NGAL (neutrophil gelatinase-associated lipocalin) levels have been shown to predict renal damage in various medical conditions. The...
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Reduction in NGAL at 48 h predicts the progression to CKD in patients with septic associated AKI: a single-center clinical study
BackgroundIn this study, our objective was to investigate the predictive value of serum and urine fluctuations of neutrophil gelatinase-associated...
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Negative symptoms and neurocognition in drug-naïve schizophrenia: moderating role of plasma neutrophil gelatinase-associated lipocalin (NGAL) and interferon-gamma (INF-γ)
Previous studies reported that peripheral inflammation was associated with cognitive performance and brain structure in schizophrenia. However, the...
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Serum neutrophil gelatinase-associated lipocalin (NGAL) as a diagnostic tool in pediatric acute appendicitis: a prospective validation study
IntroductionNGAL has recently been studied as a biomarker in the diagnostic context of pediatric acute appendicitis (PAA), although existing series...
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The Use of Neutrophil Gelatinase–Associated Lipocalin (NGAL) as a Diagnostic and Prognostic Biomarker in Urinary Tract Obstruction: a Systematic Review
Purpose of ReviewThe early recognition of urinary tract obstruction (UTO) is vital in order to prevent mortality and morbidity associated with an...
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Diagnostic value of neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for detection of renal failure in hypertensives: a case–control study in a regional hospital in Ghana
BackgroundRenal failure is one of the most serious vascular effects of hypertension. For better therapy and prevention of complications, early kidney...
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Association of significantly elevated plasma levels of NGAL and IGFBP4 in patients with diabetic nephropathy
BackgroundDiabetic nephropathy (DN) is a type of progressive kidney disease affecting approximately 40% of patients with diabetes. Current DN...
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Development of a europium nanoparticles lateral flow immunoassay for NGAL detection in urine and diagnosis of acute kidney injury
BackgroundAKI is related to severe adverse outcomes and mortality with Coronavirus Disease 2019 (COVID-19) patients, that early diagnosed and...
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Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury
BackgroundEarly and accurate acute kidney injury (AKI) detection may improve patient outcomes and reduce health service costs. This study evaluates...
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Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) Is Elevated in Patients with Asthma and Airway Obstruction
Neutrophilic airway inflammation is one of the features of severe asthma. Neutrophil gelatinase-associated lipocalin (NGAL), or lipocalin-2, is a...
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NGAL/hepcidin-25 ratio and AKI subtypes in patients following cardiac surgery: a prospective observational study
BackgroundAcute kidney injury (AKI) subtypes combining kidney functional parameters and injury biomarkers may have prognostic value. We aimed to...
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Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis
PurposeColorectal cancer (CRC) is one most cancer type of high incidence and high mortality rate. Metastasis play an important role in survival rate...
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Serum NGAL, BNP, PTH, and albumin do not improve glomerular filtration rate estimating formulas in children
Glomerular filtration rate (GFR) is difficult to measure, and estimating formulas are notorious for lacking precision. This study aims to assess if...
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Urine NGAL and KIM-1: tubular injury markers in acute lymphoblastic leukemia survivors
IntroductionNephrotoxicity is a potential adverse effect of anticancer treatment in childhood. Cytostatics, abdominal radiotherapy, total body...
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Role of urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL), Monocyte Chemoattractant Protein-1(MCP-1), and Interleukin-6(IL-6) as biomarkers in pediatric patients with hydronephrosis
ObjectivesThe decision to surgically intervene in a hydronephrotic kidney in children is based on many debatable guidelines, some requiring repeated...
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Indexed neutrophil gelatinase associated lipocalin: a novel biomarker for the assessment of acute kidney injury
IntroductionAcute kidney injury (AKI) is a clinically relevant and common complication among patients with acute coronary syndrome. Neutrophil...
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Plasma Neutrophil Gelatinase-Associated Lipocalin (2–0) Index: A Precise and Sensitive Predictor of Acute Kidney Injury in Children Undergoing Cardiopulmonary Bypass
ObjectivesTo detect the efficacy of neutrophil gelatinase-associated lipocalin (NGAL) in the early prediction of acute kidney injury (AKI) in...