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Quantification of bowel ischaemia using real-time multispectral Single Snapshot Imaging of Optical Properties (SSOP)
BackgroundSingle snapshot imaging of optical properties (SSOP) is a relatively new non-invasive, real-time, contrast-free optical imaging technology,...
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Beyond the visible spectrum – applying 3D multispectral full-body imaging to the VirtoScan system
Multispectral photography offers a wide range of applications for forensic investigations. It is commonly used to detect latent evidence and to...
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Fluorescence-guided radical prostatectomy
Robotic-assisted laparoscopic radical prostatectomy represents one of the most common operations in urologic oncology and involves several critical...
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Near-infrared fluorescence-assisted superficial inguinal lymph-node excision for low-risk penile cancer
ObjectiveIdentification of superficial inguinal lymph nodes during low-risk penile cancer surgery using near-infrared (NIR) fluorescence to improve...
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Highlighting the Undetectable — Fluorescence Molecular Imaging in Gastrointestinal Endoscopy
AbstractFlexible high-definition white-light endoscopy is the current gold standard in screening for cancer and its precursor lesions in the...
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Click-on fluorescence detectors: using robotic surgical instruments to characterize molecular tissue aspects
Fluorescence imaging is increasingly being implemented in surgery. One of the drawbacks of its application is the need to switch back-and-forth...
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Targeted optical fluorescence imaging: a meta-narrative review and future perspectives
PurposeThe aim of this review is to give an overview of the current status of targeted optical fluorescence imaging in the field of oncology,...
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Novel observations in choroidal osteoma by multispectral imaging: a pilot case series
PurposeTo identify novel tumor-specific features of ossification by using multispectral imaging (MSI) in patients diagnosed with choroidal osteoma.
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Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model
BackgroundWith the rise of prostate-specific membrane antigen (PSMA) radioguided surgery, which is performed using a microdosing regime, demand for...
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Brightfield multiplex immunohistochemistry with multispectral imaging
Brightfield microscopy is the preferred method of pathologists for diagnosing solid tumors, utilizing common staining techniques such as hematoxylin...
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Near-infrared fluorescence imaging with indocyanine green to assess the blood supply of the reconstructed gastric conduit to reduce anastomotic leakage after esophagectomy: a literature review
The blood supply of the right gastroepiploic artery after esophagectomy with gastric tube reconstruction is essential for avoiding anastomotic...
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Central serous chorioretinopathy: updates in the pathogenesis, diagnosis and therapeutic strategies
Central serous chorioretinopathy (CSCR), first described by Albrecht von Graefe in 1866, is characterized by focal serous detachment of the neural...
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Multi-wavelength fluorescence imaging with a da Vinci Firefly—a technical look behind the scenes
The field of fluorescence-guided surgery builds on colored fluorescent tracers that have become available for different clinical applications....
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A fluorogenic micrococcal nuclease-based probe for fast detection and optical imaging of Staphylococcus aureus in prosthetic joint and fracture-related infections
PurposeStaphylococcus aureus is the most common and impactful multi-drug resistant pathogen implicated in (periprosthetic) joint infections (PJI)...
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Multispectral quantitative immunohistochemical analysis of tumor-infiltrating lymphocytes in relation to programmed death-ligand 1 expression in triple-negative breast cancer
BackgroundProgrammed death-ligand 1 (PD-L1) expression on immune cells (ICs) is a predictive marker for PD-L1 checkpoint blockade in patients with...
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Monocyte infiltration is an independent positive prognostic biomarker in vulvar squamous cell carcinoma
BackgroundVulvar squamous cell carcinoma (VSCC) arises after an HPV infection or the mutation of p53 or other driver genes and is treated by...
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Spatial immune composition of tumor microenvironment in patients with pancreatic cancer
This study examined the composition of the immune microenvironment at different sites within resected pancreas specimens from patients with...
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Molecular fluorophores for in vivo bioimaging in the second near-infrared window
PurposeThis systematic review aims to summarize the current developments of fluorescence and chemi/bioluminescence imaging based on the molecular...
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Robotic radioguided surgery: toward full integration of radio- and hybrid-detection modalities
PurposeIncreasingly more laparoscopic surgical procedures are performed with robotic platforms, even becoming the standard for some indications....
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Extra-islet cells expressing insulin or glucagon in the pancreas of young organ donors
AimsThe existence of insulin- or glucagon-expressing extra-islet endocrine cells scattered in the pancreas is well-known, but they have been sparsely...
