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1. The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy

   Various post-translationally modified (PTM) proteoforms of alpha-synuclein (aSyn)—including C-terminally truncated (CTT) and Serine 129...

   Tim E. Moors, Christina A. Maat, ... Wilma D. J. van de Berg in Acta Neuropathologica

   Article Open access 11 June 2021
   

2. Quantum Dot-Based Simultaneous Multicolor Imaging

   Quantum dots have attracted a great deal of attention among researchers in optical imaging because of their unique physicochemical properties. Their...

   Wenxia Wang, Zhen Liu, **aoli Lan in Molecular Imaging and Biology

   Article 16 September 2019
   

3. Prognostic values of tissue-resident CD8⁺T cells in human hepatocellular carcinoma and intrahepatic cholangiocarcinoma

   Background

   Tissue-resident CD8 ⁺ T cells (CD103 ⁺ CD8 ⁺ T cells) are the essential effector cell population of anti-tumor immune response in tissue...

   Lujun Chen, Hao Huang, ... Chang** Wu in World Journal of Surgical Oncology

   Article Open access 06 April 2023
   

4. Myeloid-derived suppressor cells in gastroenteropancreatic neuroendocrine neoplasms

   Background

   Expanded myeloid-derived suppressor cells (MDSCs) correlate with disseminated metastases and poor prognosis in various human cancers....

   Man Liu, Yixuan Zhang, ... Jie Chen in Endocrine

   Article 03 October 2020
   

5. Characteristic differences in the abundance of tumor-infiltrating lymphocytes and intratumoral develo** T cells in thymoma, with special reference to PD-1 expression

   Purpose

   Though programmed cell death-1 (PD-1) inhibitors mainly target tumor-infiltrating lymphocytes (TILs) expressing PD-1, develo** T cells in...

   Tatsuo Furuya, Shunta Ishihara, ... Masayoshi Inoue in Cancer Immunology, Immunotherapy

   Article 15 April 2023
   

6. The relationship between peripheral T follicular helper cells and disease severity in systemic sclerosis

   We aimed to investigate the association between follicular T helper cells (Tfh) and disease severity in systemic sclerosis (SSc), a chronic...

   Melek Sahinoglu, Gokhan Sargin, ... Taskin Senturk in Clinical and Experimental Medicine

   Article Open access 27 January 2024

7. Clinical Significance of SIRPα Expression on Tumor-Associated Macrophages in Patients with Lung Squamous Cell Carcinoma

   Background

   Signal-regulatory protein alpha (SIRPα) is an immune checkpoint molecule expressed on macrophages that functions to inhibit phagocytosis by...

   Taichi Nagano, Kazuki Takada, ... Tomoharu Yoshizumi in Annals of Surgical Oncology

   Article 29 June 2024
   

8. New insight on the correlation of immune landscapes with immune markers expression in different risk classification of gastrointestinal stromal tumors

   Background

   The immune landscapes of gastrointestinal stromal tumors (GISTs) are still unclear. We aimed to explore the immune status of GISTs with...

   Qiang Zhang, **angfei Sun, ... **nyu Qin in Journal of Gastroenterology

   Article 24 March 2023
   

9. Augmented PFKFB3-mediated glycolysis by interferon-γ promotes inflammatory M1 polarization through the JAK2/STAT1 pathway in local vascular inflammation in Takayasu arteritis

   Background

   Takayasu arteritis (TAK) is characterized by pro-inflammatory M1 macrophage infiltration and increased interferon (IFN)-γ expression in...

   Rongyi Chen, **ghua Wang, ... **ufang Kong in Arthritis Research & Therapy

   Article Open access 12 December 2022
   

10. Case report of a pediatric medulloblastoma with concurrent MYC and MYCN subclonal amplification in distinct populations of neoplastic cells

    Medulloblastomas (MDBs) are classified into molecular groups showing peculiar immunohistochemical and genetic features and distinct DNA methylation...

    Simone Minasi, Francesca Gianno, ... Francesca Romana Buttarelli in Virchows Archiv

    Article 22 May 2023
    

11. Invasive papillary carcinoma of the breast: a rare case report

    Background

    Invasive Papillary Carcinomas (IPC) are rare and account for approximately 0.5% of all invasive breast carcinomas. Most of them are seen in...

    Pratibha Issar, M. Ravindranath, Manish Dewangan in Egyptian Journal of Radiology and Nuclear Medicine

    Article Open access 08 October 2021
    

12. Role of PLK1/NUMB/NOTCH in epithelial-mesenchymal transition in human melanoma

    Polo-like kinase 1 (PLK1), a serine/threonine kinase, is overexpressed in melanoma and its expression has been associated with poor disease...

    Gagan Chhabra, Chandra K. Singh, ... Nihal Ahmad in npj Precision Oncology

    Article Open access 06 January 2024
    

13. CD57-positive CD8 + T cells define the response to anti-programmed cell death protein-1 immunotherapy in patients with advanced non-small cell lung cancer

    Immune checkpoint inhibitors have transformed the treatment landscape of non-small cell lung cancer (NSCLC). However, accurately identifying patients...

    Wenjia Sun, Fengqi Qiu, ... Jianya Zhou in npj Precision Oncology

    Article Open access 31 January 2024
    

14. Electroacupuncture Promotes Angiogenesis in Mice with Cerebral Ischemia by Inhibiting miR-7

    Objective

    To observe the angiogenesis effect of electroacupuncture (EA) at Shuigou acupoint (GV 26) in the treatment of cerebral ischemia, and explore...

    Qian Yu, Shi Shu, ... Shuang Zhou in Chinese Journal of Integrative Medicine

    Article 27 March 2024

15. Dynamic Alteration in HLA-E Expression and Soluble HLA-E via Interaction with Natural Killer Cells in Gastric Cancer

    Background

    Some reports showed the immune tolerance of soluble human leukocyte antigen E (HLA-E), but the role that soluble HLA-E plays in gastric...

    Takeshi Morinaga, Masaaki Iwatsuki, ... Hideo Baba in Annals of Surgical Oncology

    Article 23 September 2022
    

16. Bone marrow clonal hematopoiesis is highly prevalent in blastic plasmacytoid dendritic cell neoplasm and frequently sharing a clonal origin in elderly patients

    Myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) are reported in up to 20% patients with blastic plasmacytoid dendritic cell...

    Mahsa Khanlari, C. Cameron Yin, ... Sa A. Wang in Leukemia

    Article 12 March 2022
    

17. Semi-automated validation and quantification of CTLA-4 in 90 different tumor entities using multiple antibodies and artificial intelligence

    CTLA-4 is an inhibitory immune checkpoint receptor and a negative regulator of anti-tumor T-cell function. This study is aimed for a comparative...

    David Dum, Tjark L. C. Henke, ... Niclas C. Blessin in Laboratory Investigation

    Article Open access 29 January 2022
    

18. Genetic and cytometric analyses of subcutaneous adipose tissue in patients with hemophilia and HIV-associated lipodystrophy

    Background

    The authors recently performed plastic surgeries for a small number of patients with hemophilia, HIV infection, and morphologic evidence of...

    Takanobu Mashiko, Kunihisa Tsukada, ... Kotaro Yoshimura in AIDS Research and Therapy

    Article Open access 04 March 2022
    

19. Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo

    Background

    The immunological composition of the tumor microenvironment has a decisive influence on the biological course of cancer and is therefore of...

    Sandra Genduso, Vera Freytag, ... Tobias Lange in Journal of Hematology & Oncology

    Article Open access 17 March 2023
    

20. Reverted exhaustion phenotype of circulating lymphocytes as immune correlate of anti-PD1 first-line treatment in Hodgkin lymphoma

    While classical Hodgkin lymphoma (HL) is highly susceptible to anti-programmed death protein 1 (PD1) antibodies, the exact modes of action remain...

    Maria A. Garcia-Marquez, Martin Thelen, ... Hans A. Schlößer in Leukemia

    Article Open access 28 September 2021