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Biodistribution and dosimetry for combined [177Lu]Lu-PSMA-I&T/[225Ac]Ac-PSMA-I&T therapy using multi-isotope quantitative SPECT imaging
PurposeQuantitative SPECT for patient-specific dosimetry is a valuable tool in the scope of radionuclide therapy, although its clinical application...
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Imaging cancer metabolism using magnetic resonance
The challenge in clinical oncology is to select the most appropriate treatment for an individual patient. Transcriptome and metabolite profiling have...
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Diagnostic imaging of the diabetic foot: an EANM evidence-based guidance
PurposeConsensus on the choice of the most accurate imaging strategy in diabetic foot infective and non-infective complications is still lacking....
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Develo** a novel positronium biomarker for cardiac myxoma imaging
PurposeCardiac myxoma (CM), the most common cardiac tumor in adults, accounts for 50–75% of benign cardiac tumors. The diagnosis of CM is often...
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Development of a multi faceted platform containing a tetrazine, fluorophore and chelator: synthesis, characterization, radiolabeling, and immuno-SPECT imaging
BackgroundCombining optical (fluorescence) imaging with nuclear imaging has the potential to offer a powerful tool in personal health care, where...
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PET/MRI imaging in neuroendocrine neoplasm
Molecular imaging plays a vital role in the management of neuroendocrine neoplasms (NENs). Somatostatin receptor (SSTR) PET is critical for...
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Electron Spin Resonance Probe Incorporation into Bioinks Permits Longitudinal Oxygen Imaging of Bioprinted Constructs
PurposeBioprinting is an additive manufacturing technology analogous to 3D printing. Instead of plastic or resin, cell-laden hydrogels are used to...
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Performance evaluation of a novel multi-pinhole collimator on triple-NaI-detector SPECT/CT for dedicated myocardial imaging
BackgroundIn this study we evaluated the imaging capabilities of a novel Multi-pinhole collimator (MPH-Cardiac) specially designed for nuclear...
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High-multiplex tissue imaging in routine pathology—are we there yet?
High-multiplex tissue imaging (HMTI) approaches comprise several novel immunohistological methods that enable in-depth, spatial single-cell...
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Comparison of the dosimetry of scandium-43 and scandium-44 patient organ doses in relation to commonly used gallium-68 for imaging neuroendocrine tumours
BackgroundSeveral research groups have explored the potential of scandium radionuclides for theragnostic applications due to their longer half-lives...
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Radiolabeled florescent-magnetic graphene oxide nanosheets: probing the biodistribution of a potential PET-MRI hybrid imaging agent for detection of fibrosarcoma tumor
PurposeRadiolabeled graphene oxide (GO) nanosheets has been one of the most extensively studied nanoplatform for in vivo radioisotope delivery....
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Quantitation of dynamic total-body PET imaging: recent developments and future perspectives
BackgroundPositron emission tomography (PET) scanning is an important diagnostic imaging technique used in disease diagnosis, therapy planning,...
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Mitigating SUV uncertainties using total body PET imaging
PurposeStandardised uptake values (SUV) are commonly used to quantify 18 F-FDG lesion uptake. However, SUVs may suffer from several uncertainties and...
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Advances and prospects in deuterium metabolic imaging (DMI): a systematic review of in vivo studies
BackgroundDeuterium metabolic imaging (DMI) has emerged as a promising non-invasive technique for studying metabolism in vivo . This review aims to...
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Unsupervised learning to characterize patients with known coronary artery disease undergoing myocardial perfusion imaging
PurposePatients with known coronary artery disease (CAD) comprise a heterogenous population with varied clinical and imaging characteristics....
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A radiohybrid theranostics ligand labeled with fluorine-18 and lutetium-177 for fibroblast activation protein-targeted imaging and radionuclide therapy
PurposeA series of radiotracers targeting fibroblast activation protein (FAP) with great pharmacokinetics have been developed for cancer diagnosis...
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Improved Performance of PET Myocardial Perfusion Imaging Compared to SPECT in the Evaluation of Suspected CAD
Purpose of ReviewMyocardial perfusion imaging (MPI) with single photon emission computed tomography (SPECT) has played a central role in the...
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Assessment of the alpha 7 nicotinic acetylcholine receptor as an imaging marker of cardiac repair-associated processes using NS14490
BackgroundCardiac repair and remodeling following myocardial infarction (MI) is a multifactorial process involving pro-reparative inflammation,...
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Use of imaging-based dosimetry for personalising radiopharmaceutical therapy of cancer
Theranostics – i.e., the combination of molecular imaging and radiopharmaceutical therapy of cancer targeting a common biological feature – is a...
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Practical Guidance for Develo** Small-Molecule Optical Probes for In Vivo Imaging
The WMIS Education Committee (2019–2022) reached a consensus that white papers on molecular imaging could be beneficial for practitioners of...
