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Gastrointestinale Stromatumoren
For more than 20 years gastrointestinal stromal tumors (GIST) have been a paradigm for a targeted treatment with tyrosine kinase inhibitors....
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Mesenchymale Tumoren im Gastrointestinaltrakt
Mesenchymal tumors of the gastrointestinal tract are by far less frequent than epithelial neoplasms. The most frequent are gastrointestinal stromal...
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Neuroendokrine Neoplasien
The gastrointestinal tract represents, together with the lung, the most common site for the occurrence of neuroendocrine neoplasms (NEN). NEN include...
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Diagnose und Therapie seltener Hodentumoren am Beispiel des malignen Mesothelioms der Tunica vaginalis testis und Sertoli-Zell-Tumoren
BackgroundRare tumors of the testis not originating from germinal epithelium are a diagnostic and therapeutic challenge.
ObjectivesTo present...
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Hypophysenadenome – nicht immer benigner Natur
BackgroundWith a prevalence of 80–100/100,000, pituitary adenomas are more frequent than generally thought; however, they are frequently diagnosed...
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Keimzell- und Gonadenstromatumoren des Hodens
Earlier revisions of the WHO classification of testicular tumors, which was originally published in 1977, contained only minor additions. In the WHO...
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Gastrointestinale Stromatumoren
Gastrointestinal stromal tumors (GIST) are very rare. However, they may be a challenge with respect to diagnosis and treatment. In most cases,...
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Gastrointestinale Stromatumoren des Magens und ihre Vorstufen
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors in the gastrointestinal tract although they are much less frequent than...
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Fallstricke bei der histopathologischen Diagnostik des Endometriumkarzinoms und seiner Vorstufen
Making an incorrect histopathological diagnosis of an endometrial lesion may lead to unwanted loss of fertility and therapy-associated morbidity;...
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Klinische Pathologie des Mammakarzinoms
The pathological characterization of breast cancers today extends beyond traditional ty**, staging, and grading. Via immunohistochemistry,...
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Grading von Weichgewebe- und Knochensarkomen
Malignancy grading is an essential element in the classification of sarcomas. It correlates with the prognosis of the disease and the risk of...
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Grading neuroendokriner Tumoren
The current WHO classification of neuroendocrine tumors (NET) differentiates between typical carcinoids (low grade NET), atypical carcinoids...
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Grading gynäkologischer Tumoren
Histopathological assessment of the tumor grade and cell type is central to the management and prognosis of various gynecological malignancies....
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Diagnose, Prognose und Prädiktion nicht-kleinzelliger Lungenkarzinome
Tumor diagnostics are based on histomorphology, immunohistochemistry and molecular pathological analysis of mutations, translocations and...
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Proliferationsbestimmung beim Mammakarzinom durch den immunhistochemischen Nachweis von Ki-67
Gene expression profiling has demonstrated the prognostic relevance of genes associated with proliferation in breast cancer. The immunohistochemical...
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Gestationsbedingte Trophoblasttumoren
Despite a low incidence of 1:100.000 pregnancies gestational trophoblastic disease can be associated with severe maternal morbidity. Risk factors are...