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Somatic cell count in bovine quarter milk samples culture positive for various Staphylococcus species
BackgroundNon-aureus staphylococci (NAS) are the most prevalent group of bacteria isolated in bovine mastitis milk in Finland and many other...
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Culture Models to Investigate Mechanisms of Milk Production and Blood-Milk Barrier in Mammary Epithelial Cells: a Review and a Protocol
Mammary epithelial cells (MECs) are the only cell type that produces milk during lactation. MECs also form less-permeable tight junctions (TJs) to...
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Presence of pathogen DNA in milk harvested from quarters is associated to changes in cows’ milk yield and composition
BackgroundIntramammary infection is the result of invasion and multiplication of microorganisms in the mammary gland and commonly leads to mastitis...
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Evaluation of oxidative stress, compositional and biochemical changes in milk and serum of cows with subclinical mastitis
Subclinical mastitis (SCM) has a detrimental impact on cow’s milk characteristics. The study was to investigate the consequences of SCM on milk...
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Valine Treatment Enhances Antimicrobial Component Production in Mammary Epithelial Cells and the Milk of Lactating Goats Without Influencing the Tight Junction Barrier
The production of antimicrobial components and the formation of less-permeable tight junctions (TJs) are important in the defense system of lactating...
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Cows with diverging haplotypes show differences in differential milk cell count, milk parameters and vaginal temperature after S. aureus challenge but not after E. coli challenge
BackgroundIn dairy cattle, mastitis causes high financial losses and impairs animal well-being. Genetic selection is used to breed cows with reduced...
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Metataxonomic analysis and host proteome response in dairy cows with high and low somatic cell count: a quarter level investigation
Host response to invasive microbes in the bovine udder has an important role on the animal health and is essential to the dairy industry to ensure...
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Milk miRNA expression in buffaloes as a potential biomarker for mastitis
BackgroundBuffaloes have the highest potential for production due to a promising gene pool that is being enhanced and upgraded. Mastitis is a...
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Genes and pathways revealed by whole transcriptome analysis of milk derived bovine mammary epithelial cells after Escherichia coli challenge
Mastitis, inflammation of the mammary gland, is the costliest disease in dairy cattle and a major animal welfare concern. Mastitis is usually caused...
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Milk fat miRNome changes in response to LPS challenge in Holstein cows
Mastitis is an inflammatory disease in dairy cows, causing economic losses and reducing animal welfare. In order to contribute for the discovery of...
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Evaluation and application of a milk antibody ELISA for assessing the prevalence and incidence of bovine tuberculosis in dairy herds in Hubei Province, China
Bovine tuberculosis (bTB) is a chronic zoonotic disease that is endemic in China. Current in-vitro tests for bTB are mainly based on blood assays....
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Prescribing and sales of intramammary antimicrobials in Ireland in 2019 and 2020: the role of milk purchasers
BackgroundIn Ireland between 2008 and 2022, intramammary antimicrobial (AM) products could be prescribed by a veterinary practitioner under what was...
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Absence of changes in the milk microbiota during Escherichia coli endotoxin induced experimental bovine mastitis
Changes in the milk microbiota during the course of mastitis are due to the nature of a sporadic occurring disease difficult to study. In this study...
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The Role of Cow’s Milk Consumption in Breast Cancer Initiation and Progression
Purpose of ReviewThis review evaluates cow milk’s impact on breast carcinogenesis by linking recent epidemiological evidence and new insights into...
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Current Approaches in Cardiac Repair: Somatic and Stem Cell Exosomes
Purpose of ReviewMyocardial infarction, which is the most important clinical sign of coronary artery disease, is one of the leading causes of global...
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Somatic ARAF mutations in pediatric Langerhans cell histiocytosis: clinicopathologic, genetic and functional profiling
ARAF mutations have been identified in a limited subset of patients with Langerhans cell histiocytosis (LCH), a rare disorder characterized by...
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Prevalence of udder pathogens in milk samples from Norwegian dairy cows recorded in a national database in 2019 and 2020
BackgroundIdentification of aetiological agents of mastitis in dairy cattle is important for herd management of udder health. In Norway, results from...
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Milk Antitrypsin Activity During Clinical and Experimental Bovine Mastitis
Milk trypsin-inhibitor levels were followed during clinical and experimental endotoxin-induced mastitis. Milk trypsin-inhibitor level proved to be a...
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Soluble CD14 produced by bovine mammary epithelial cells modulates their response to full length LPS
Bovine mastitis remains a major disease in cattle world-wide. In the mammary gland, mammary epithelial cells (MEC) are sentinels equipped with...
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Reproducible isolation of bovine mammary macrophages for analysis of host pathogen interactions
BackgroundMacrophages residing in milk are vital during intramammary infections. This study sought to develop a method enabling the investigation of...